Lessons from knockout and transgenic mice for infertility in men. (Q34083276)

30 July 2017

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title

Lessons from knockout and transgenic mice for infertility in men. (English)

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30 July 2017

Venables JP

1

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30 July 2017

Cooke HJ

series ordinal

2

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30 July 2017

publication date

1 October 2000

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Journal of Endocrinological Investigation

30 July 2017

published in

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30 July 2017

volume

23

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30 July 2017

issue

9

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30 July 2017

page(s)

584-591

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The hypogonadal mouse: reproductive functions restored by gene therapy

30 July 2017

cites work

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Male development of chromosomally female mice transgenic for Sry.

21 January 2018

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Sry requires a CAG repeat domain for male sex determination in Mus musculus

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Normal spermatogenesis in mice lacking the testis-specific linker histone H1t.

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Role of Ahch in gonadal development and gametogenesis

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Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene.

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RNA-binding protein TIAR is essential for primordial germ cell development

21 January 2018

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The LIM homeobox gene Lhx9 is essential for mouse gonad formation

21 January 2018

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The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis

21 January 2018

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Post-transcriptional regulation of the meiotic Cdc25 protein Twine by the Dazl orthologue Boule

21 January 2018

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DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis

21 January 2018

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Male sterility and enhanced radiation sensitivity in TLS(-/-) mice

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03343780

New gene family defined by MORC, a nuclear protein required for mouse spermatogenesis

21 January 2018

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The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility

21 January 2018

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Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03343780

The mouse RecA-like gene Dmc1 is required for homologous chromosome synapsis during meiosis

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03343780

Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03343780

Mammalian MutS homologue 5 is required for chromosome pairing in meiosis

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03343780

Apoptosis regulator bcl-w is essential for spermatogenesis but appears otherwise redundant

21 January 2018

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Arrest of spermatogenesis and defective breast development in mice lacking A-myb

21 January 2018

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Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

21 January 2018

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Meiotic pachytene arrest in MLH1-deficient mice

21 January 2018

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Cyclin A1 is required for meiosis in the male mouse

21 January 2018

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CREM, a master-switch of the transcriptional cascade in male germ cells

21 January 2018

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Specific aspects of the ubiquitin system in spermatogenesis

21 January 2018

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Defects in nuclear and cytoskeletal morphology and mitochondrial localization in spermatozoa of mice lacking nectin-2, a component of cell-cell adherens junctions

21 January 2018

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The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis

21 January 2018

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Fertilization defects in sperm from mice lacking fertilin beta.

21 January 2018

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The roles of RNA-binding proteins in spermatogenesis and male infertility.

21 January 2018

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Premature translation of protamine 1 mRNA causes precocious nuclear condensation and arrests spermatid differentiation in mice

21 January 2018

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Deletion and expression analysis of AZFa genes on the human Y chromosome revealed a major role for DBY in male infertility

21 January 2018

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Sperm-specific expression of angiotensin-converting enzyme (ACE) is mediated by a 91-base-pair promoter containing a CRE-like element

21 January 2018

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Species variation in the testicular angiotensin converting enzyme promoter studied in transgenic mice.

21 January 2018

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A novel 14-base-pair regulatory element is essential for in vivo expression of murine beta4-galactosyltransferase-I in late pachytene spermatocytes and round spermatids

21 January 2018

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Characterization of the testis-specific gene 'calmegin' promoter sequence and its activity defined by transgenic mouse experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03343780

Expression of the rat testis-specific histone H1t gene in transgenic mice. One kilobase of 5'-flanking sequence mediates correct expression of a lacZ fusion gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03343780

Testis expression of hormone-sensitive lipase is conferred by a specific promoter that contains four regions binding testicular nuclear proteins

21 January 2018

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Developmentally regulated expression of Hsp70-2 and a Hsp70-2/lacZ transgene during spermatogenesis

21 January 2018

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The mouse inhibin alpha-subunit promoter directs SV40 T-antigen to Leydig cells in transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03343780

Germ line-specific expression of intracisternal A-particle retrotransposons in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03343780

Sequences 5' of the basement membrane laminin beta 1 chain gene (LAMB1) direct the expression of beta-galactosidase during development of the mouse testis and ovary.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03343780

Germline-specific expression of the Oct-4/green fluorescent protein (GFP) transgene in mice

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03343780

Regulation of Pdha-2 expression is mediated by proximal promoter sequences and CpG methylation

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03343780

Transcriptional regulatory regions of testis-specific PGK2 defined in transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03343780

Haploid male germ cells show no susceptibility to transformation by simian virus 40 large tumour antigen in transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03343780

Analysis of the mouse protamine 1 promoter in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03343780

Boar proacrosin expressed in spermatids of transgenic mice does not reach the acrosome and disrupts spermatogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03343780

Haploid-specific transcription of protamine-myc and protamine-T-antigen fusion genes in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03343780

Round spermatid-specific transcription of the mouse SP-10 gene is mediated by a 294-base pair proximal promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03343780

Temporal and spatial control of the Sycp1 gene transcription in the mouse meiosis: regulatory elements active in the male are not sufficient for expression in the female gonad

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03343780

Real-time observation of acrosomal dispersal from mouse sperm using GFP as a marker protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03343780

Spermatocyte-specific transcription by calmodulin gene II promoter in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03343780

Spermiogenesis is impaired in mice bearing a targeted mutation in the protein phosphatase 1cgamma gene

21 January 2018

1 reference

12 December 2020

HSP70-2 heat-shock protein of mouse spermatogenic cells.

1 reference

12 December 2020

Separate elements in the 3' untranslated region of the mouse protamine 1 mRNA regulate translational repression and activation during murine spermatogenesis

1 reference

12 December 2020

An upstream region of the rat spermatogenesis-specific heat-shock-like Hst70 gene confers testis-specific expression in transgenic mice

1 reference

12 December 2020

The rat proenkephalin germ line promoter contains multiple binding sites for spermatogenic cell nuclear proteins.

1 reference

12 December 2020

Mammalian spermatogenesis investigated by genetic engineering

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12 December 2020

Testis-specific expression of the rat histone Hlt gene in transgenic mice

1 reference

12 December 2020

Animal models that mimic human male reproductive defects

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12 December 2020

Directed expression of an oncogene to Sertoli cells in transgenic mice using mullerian inhibiting substance regulatory sequences

1 reference

12 December 2020

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

12 December 2020

Promoter mapping of the mouse Tcp-10bt gene in transgenic mice identifies essential male germ cell regulatory sequences

1 reference

12 December 2020

Expression of an Xist promoter-luciferase construct during spermatogenesis and in preimplantation embryos: regulation by DNA methylation.

1 reference

12 December 2020

Expression of a mouse Zfy-1/lacZ transgene in the somatic cells of the embryonic gonad and germ cells of the adult testis

1 reference

12 December 2020

A 252 bp upstream region of the rat spermatocyte-specific hst70 gene is sufficient to promote expression of the hst70-CAT hybrid gene in testis and brain of transgenic mice

1 reference

12 December 2020

Regulatory role of p27kip1 in the mouse and human testis

1 reference

12 December 2020

Targeted mutagenesis of the endogenous mouse Mis gene promoter: in vivo definition of genetic pathways of vertebrate sexual development

1 reference

12 December 2020

The mouse homolog of Drosophila Vasa is required for the development of male germ cells

1 reference

12 December 2020

Human testis-specific lactate dehydrogenase-C promoter drives overexpression of mouse lactate dehydrogenase-1 cDNA in testes of transgenic mice

1 reference

12 December 2020

Xist-deficient mice are defective in dosage compensation but not spermatogenesis

1 reference

12 December 2020

Male germ cell expression of murine beta 4-galactosyltransferase. A 796-base pair genomic region, containing two cAMP-responsive element (CRE)-like elements, mediates male germ cell-specific expression in transgenic mice.

1 reference

12 December 2020

Expression of mouse protamine 1 genes in transgenic mice

1 reference

12 December 2020

The human MLH1 cDNA complements DNA mismatch repair defects in Mlh1-deficient mouse embryonic fibroblasts

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12 December 2020

Transgenic mice demonstrate a testis-specific promoter for lactate dehydrogenase, LDHC

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12 December 2020

Sperm from mice carrying a targeted mutation of the acrosin gene can penetrate the oocyte zona pellucida and effect fertilization

1 reference

12 December 2020

Atm deficiency results in severe meiotic disruption as early as leptonema of prophase I.

1 reference

12 December 2020

A cell- and developmental stage-specific promoter drives the expression of a truncated c-kit protein during mouse spermatid elongation.

1 reference

12 December 2020

Localization of upstream elements involved in transcriptional regulation of the rat testis-specific histone H1t gene in somatic cells

1 reference

12 December 2020

Tissue-specific expression of the rat androgen-binding protein/sex hormone-binding globulin gene in transgenic mice

1 reference

12 December 2020

ATR disruption leads to chromosomal fragmentation and early embryonic lethality

1 reference

12 December 2020

Growth retardation, DNA repair defects, and lack of spermatogenesis in BRCA1-deficient mice

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF03343780

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Dimensions Publication ID

30 July 2017

1010372365

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