DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis (Q33814324)

29 July 2017

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title

DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis (English)

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29 July 2017

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Dasika GK

1

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29 July 2017

Lin SC

2

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29 July 2017

Zhao S

3

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29 July 2017

Sung P

4

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29 July 2017

Tomkinson A

5

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29 July 2017

Lee EY

6

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29 July 2017

language of work or name

English

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publication date

1 December 1999

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29 July 2017

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29 July 2017

volume

18

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29 July 2017

issue

55

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29 July 2017

page(s)

7883-7899

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BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair

29 July 2017

cites work

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

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Atm-deficient mice: a paradigm of ataxia telangiectasia

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Partial rescue of the prophase I defects of Atm-deficient mice by p53 and p21 null alleles.

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7 January 2021

DNA end-joining catalyzed by human cell-free extracts

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7 January 2021

Role of the human RAD51 protein in homologous recombination and double-stranded-break repair

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7 January 2021

Synergistic actions of Rad51 and Rad52 in recombination and DNA repair.

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7 January 2021

Xrcc3 is required for assembly of Rad51 complexes in vivo

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7 January 2021

Replication checkpoint enforced by kinases Cds1 and Chk1.

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7 January 2021

Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

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7 January 2021

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

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7 January 2021

Basis for the checkpoint signal specificity that regulates Chk1 and Cds1 protein kinases

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7 January 2021

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7 January 2021

The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast

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7 January 2021

DNA-dependent protein kinase-independent activation of p53 in response to DNA damage

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7 January 2021

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

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7 January 2021

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

DNA looping by Ku and the DNA-dependent protein kinase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Ku80 is required for immunoglobulin isotype switching

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Recombinational repair in yeast: functional interactions between Rad51 and Rad54 proteins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The SbcCD nuclease of Escherichia coli is a structural maintenance of chromosomes (SMC) family protein that cleaves hairpin DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The sbcC and sbcD genes of Escherichia coli encode a nuclease involved in palindrome inviability and genetic recombination.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

DNA end-joining: from yeast to man

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The Nijmegen breakage syndrome protein is essential for Mre11 phosphorylation upon DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Selective loss of dopaminergic nigro-striatal neurons in brains of Atm-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Abnormal centrosome amplification in the absence of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Sequence-specific DNA binding by Ku autoantigen and its effects on transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Yeast Ku as a regulator of chromosomal DNA end structure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Requirement for an interaction of XRCC4 with DNA ligase IV for wild-type V(D)J recombination and DNA double-strand break repair in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

DNA ligase IV binds to XRCC4 via a motif located between rather than within its BRCT domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The S / M checkpoint at 37˚C and the recovery of viability of the mutant pol δ ts3 require the crb2 + /rhp9 + gene in fission yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Mammalian telomeres end in a large duplex loop

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The many interfaces of Mre11

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Ku86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Cell cycle control and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Direct association between the yeast Rad51 and Rad54 recombination proteins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The emerging p53 gene family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Ku-dependent nonhomologous DNA end joining in Xenopus egg extracts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Radiation effects on DNA synthesis in a defined chromosomal replicon

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Radiation down-regulates replication origin activity throughout the S phase in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Promoter specificity and stability control of the p53-related protein p73

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Structure of DNA-dependent protein kinase: implications for its regulation by DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Ku70: a candidate tumor suppressor gene for murine T cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Chromosomal double-strand break repair in Ku80-deficient cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

No requirement for V(D)J recombination in p53-deficient thymic lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

V(D)J recombination and the cell cycle.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Localization and dynamic relocalization of mammalian Rad52 during the cell cycle and in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

DNA double-strand break rejoining in xrs5 cells is more rapid in the G2 than in the G1 phase of the cell cycle.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Loss of heterozygosity induced by a chromosomal double-strand break

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

In situ visualization of DNA double-strand break repair in human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Telomere maintenance is dependent on activities required for end repair of double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Analysis of the mechanism of interaction of simian Ku protein with DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Inhibition of mammalian cell DNA synthesis by ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Radiosensitivity in ataxia-telangiectasia: a new explanation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Atm inactivation results in aberrant telomere clustering during meiotic prophase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The G(2) checkpoint is maintained by redundant pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Involvement of Brca2 in DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Isolation and characterization of the human MRE11 homologue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Catalysis of homologous DNA pairing by yeast Rad51 and Rad54 proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

G1 control in mammalian cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Mitotic DNA damage and replication checkpoints in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

ATM: from gene to function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Association of BRCA1 with Rad51 in mitotic and meiotic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Structural and functional similarities between the SbcCD proteins of Escherichia coli and the RAD50 and MRE11 (RAD32) recombination and repair proteins of yeast.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Regulation of DNA-replication origins during cell-cycle progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Interchromosomal recombination is suppressed in mammalian somatic cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Brca2 is required for embryonic cellular proliferation in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

A role for ATR in the DNA damage-induced phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Binding of double-strand breaks in DNA by human Rad52 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Cut5 is a component of the UV-responsive DNA damage checkpoint in fission yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Yeast DNA ligase IV mediates non-homologous DNA end joining

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Dual roles of ATM in the cellular response to radiation and in cell growth control.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

The mouse RecA-like gene Dmc1 is required for homologous chromosome synapsis during meiosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

UCN-01 abrogates G2 arrest through a Cdc2-dependent pathway that is associated with inactivation of the Wee1Hu kinase and activation of the Cdc25C phosphatase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Regulation of Rad51 function by c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

MDM2 suppresses p73 function without promoting p73 degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Abrogation of p53 function affects gadd gene responses to DNA base-damaging agents and starvation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203283

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203283

1 reference

Dimensions Publication ID

29 July 2017

1035749732

0 references

1 reference