Inhibition of acinar apoptosis occurs during acute pancreatitis in the human homologue DeltaF508 cystic fibrosis mouse (Q34085307)

30 July 2017

Inhibition of acinar apoptosis occurs during acute pancreatitis in the human homologue DeltaF508 cystic fibrosis mouse (English)

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30 July 2017

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Matthew J DiMagno

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30 July 2017

Sae-Hong Lee

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2

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30 July 2017

Chung Owyang

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30 July 2017

Shi-yi Zhou

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30 July 2017

language of work or name

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3 June 2010

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American Journal of Physiology - Gastrointestinal and Liver Physiology

30 July 2017

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30 July 2017

299

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30 July 2017

2

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30 July 2017

G400-12

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CFTR mediates apoptotic volume decrease and cell death by controlling glutathione efflux and ROS production in cultured mice proximal tubules.

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Inflammatory cells regulate p53 and caspases in acute pancreatitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Connections between genetics and clinical data: Role of MCP-1, CFTR, and SPINK-1 in the setting of acute, acute recurrent, and chronic pancreatitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Neutrophil apoptosis: a target for enhancing the resolution of inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Reducing extracellular pH sensitizes the acinar cell to secretagogue-induced pancreatitis responses in rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Defective organellar acidification as a cause of cystic fibrosis lung disease: reexamination of a recurring hypothesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

CFTR regulation of intracellular pH and ceramides is required for lung endothelial cell apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Defective acid sphingomyelinase pathway with Pseudomonas aeruginosa infection in cystic fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

CFTR mediates cadmium-induced apoptosis through modulation of ROS level in mouse proximal tubule cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Air pollution induces enhanced mitochondrial oxidative stress in cystic fibrosis airway epithelium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Epithelial cell apoptosis and neutrophil recruitment in acute lung injury-a unifying hypothesis? What we have learned from small interfering RNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Processing and function of CFTR-DeltaF508 are species-dependent

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

New advances in acute pancreatitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Acute pancreatitis: bench to the bedside.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

CFTR inhibition mimics the cystic fibrosis inflammatory profile

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

MUC4 expression is regulated by cystic fibrosis transmembrane conductance regulator in pancreatic adenocarcinoma cells via transcriptional and post-translational mechanisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Caerulein-induced acute pancreatitis in mice that constitutively overexpress Reg/PAP genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Significance of apoptotic cell death in systemic complications with severe acute pancreatitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Interleukin 8 secretion from monocytes of subjects heterozygous for the deltaF508 cystic fibrosis transmembrane conductance regulator gene mutation is altered

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Risk of pancreatitis with mutation of the cystic fibrosis gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Characteristic multiorgan pathology of cystic fibrosis in a long-living cystic fibrosis transmembrane regulator knockout murine model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Antagonizing XIAP-mediated caspase-3 inhibition. Achilles' heel of cancers?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Pseudomonas aeruginosa-induced apoptosis is defective in respiratory epithelial cells expressing mutant cystic fibrosis transmembrane conductance regulator.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Molecular consequences of cystic fibrosis transmembrane regulator (CFTR) gene mutations in the exocrine pancreas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Transcriptional adaptation to cystic fibrosis transmembrane conductance regulator deficiency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Hereditary pancreatitis: a model for inflammatory diseases of the pancreas.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

CFTR modulates programmed cell death by decreasing intracellular pH in Chinese hamster lung fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Activation of NF-kappaB in airway epithelial cells is dependent on CFTR trafficking and Cl- channel function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Aberrant CFTR-dependent HCO3- transport in mutations associated with cystic fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Ethanol diet increases the sensitivity of rats to pancreatitis induced by cholecystokinin octapeptide

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from an uncleavable mutant

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Mutations of the cystic fibrosis gene in patients with chronic pancreatitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

DNA fragmentation is a feature of cystic fibrosis epithelial cells: a disease with inappropriate apoptosis?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Regulation of neutrophil apoptosis--its biological significance in inflammation and the immune response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Mutant cystic fibrosis transmembrane conductance regulator inhibits acidification and apoptosis in C127 cells: possible relevance to cystic fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Mechanisms of cell death after pancreatic duct obstruction in the opossum and the rat.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

A mouse model for the delta F508 allele of cystic fibrosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Localization of the cystic fibrosis transmembrane conductance regulator in pancreas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Diminished lung injury with vascular adhesion molecule-1 blockade in choline-deficient ethionine diet-induced pancreatitis

5 July 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Secretagogue-stimulated pancreatic secretion is differentially regulated by constitutive NOS isoforms in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Endothelial nitric oxide synthase is protective in the initiation of caerulein-induced acute pancreatitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Postmitochondrial regulation of apoptosis by bicarbonate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Association of pancreas divisum and recurrent acute pancreatitis with the IVS8-5T-12TG allele of the CFTR gene and CFTR dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Dietary changes improve survival of CFTR S489X homozygous mutant mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Pancreatic response to endotoxin after chronic alcohol exposure: switch from apoptosis to necrosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Pancreatic acinar cell dysfunction in CFTR(-/-) mice is associated with impairments in luminal pH and endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Severe acute pancreatitis and reduced acinar cell apoptosis in the exocrine pancreas of mice deficient for the Cx32 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Analysis of cystic fibrosis gener product (CFTR) function in patients with pancreas divisum and recurrent acute pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Glutathione levels and BAX activation during apoptosis due to oxidative stress in cells expressing wild-type and mutant cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Acidic duodenal pH alters gene expression in the cystic fibrosis mouse pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Cell death in pancreatitis: caspases protect from necrotizing pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Cystic fibrosis transmembrane regulator gene carrier status is a risk factor for young onset pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

In cystic fibrosis homozygotes and heterozygotes, neutrophil apoptosis is delayed and modulated by diamide or roscovitine: evidence for an innate neutrophil disturbance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

A pH-sensitive, neurogenic pathway mediates disease severity in a model of post-ERCP pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Inflammation of the cystic fibrosis mouse small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Interleukin 10 reduces the severity of acute pancreatitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Exaggerated apoptosis and NF-kappaB activation in pancreatic and tracheal cystic fibrosis cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Extracellular matrix proteins protect pancreatic cancer cells from death via mitochondrial and nonmitochondrial pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Ethanol feeding alters death signaling in the pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

Functional genomic responses to cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR(delta508) in the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00061.2010

A proinflammatory, antiapoptotic phenotype underlies the susceptibility to acute pancreatitis in cystic fibrosis transmembrane regulator (-/-) mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Mutations of the CFTR Gene in Pancreatic Disease

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

CFTR gene mutations in patients suffering from acute pancreatitis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928535

Dysregulated cytokine production in human cystic fibrosis bronchial epithelial cells

28 October 2018

1 reference

12 December 2020

1 reference

12 December 2020

Immuno and functional characterization of CFTR in submandibular and pancreatic acinar and duct cells

1 reference

12 December 2020

Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis

1 reference

12 December 2020

IRES in distress: translational regulation of the inhibitor of apoptosis proteins XIAP and HIAP2 during cell stress

1 reference

12 December 2020

Altered caspase expression results in delayed neutrophil apoptosis in acute pancreatitis

1 reference

12 December 2020

Chronic alcohol consumption is a major risk factor for pancreatic necrosis in acute pancreatitis

1 reference

12 December 2020

Evidence of chronic inflammation in morphologically normal small intestine of cystic fibrosis patients

1 reference

12 December 2020

Increased risk of idiopathic chronic pancreatitis in cystic fibrosis carriers

1 reference

12 December 2020

Glibenclamide induces apoptosis through inhibition of cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channels and intracellular Ca(2+) release in HepG2 human hepatoblastoma cells

1 reference

12 December 2020

Can too much acid sour your pancreas?

1 reference

12 December 2020

Quantitation of inflammatory responses to bacteria in young cystic fibrosis and control patients

1 reference

12 December 2020

The effects of neutrophil depletion on a completely noninvasive model of acute pancreatitis-associated lung injury

1 reference

12 December 2020

Secretagogue-induced digestive enzyme activation and cell injury in rat pancreatic acini

1 reference

12 December 2020

Identifiers

DOI

10.1152/AJPGI.00061.2010

1 reference

30 July 2017

1 reference

30 July 2017

1 reference