Unbalanced Neonatal CD4(+) T-Cell Immunity (Q34091987)

31 July 2017

1 reference

title

Unbalanced Neonatal CD4(+) T-Cell Immunity (English)

1 reference

31 July 2017

Isabelle Debock

1

1 reference

31 July 2017

Véronique Flamand

series ordinal

2

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31 July 2017

publication date

27 August 2014

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31 July 2017

published in

Frontiers in Immunology

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31 July 2017

volume

5

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31 July 2017

page(s)

393

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CD4 T cells with effector memory phenotype and function develop in the sterile environment of the fetus

31 July 2017

cites work

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Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V

5 July 2018

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Early Th1 cell differentiation is marked by a Tfh cell-like transition

5 July 2018

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ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6

5 July 2018

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Autocrine transforming growth factor-β1 promotes in vivo Th17 cell differentiation

5 July 2018

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Follicular helper CD4 T cells (TFH)

5 July 2018

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Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

5 July 2018

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Yersinia enterocolitica promotes robust mucosal inflammatory T-cell immunity in murine neonates

5 July 2018

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Differentiation of effector CD4 T cell populations (*)

5 July 2018

1 reference

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5 July 2018

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Microchimerism is strongly correlated with tolerance to noninherited maternal antigens in mice

5 July 2018

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Bcl6 mediates the development of T follicular helper cells

5 July 2018

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Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

5 July 2018

1 reference

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A liposome-based mycobacterial vaccine induces potent adult and neonatal multifunctional T cells through the exquisite targeting of dendritic cells

5 July 2018

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B-cell responses to vaccination at the extremes of age.

5 July 2018

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Impaired innate and adaptive immunity to Streptococcus pneumoniae and its effect on colonization in an infant mouse model

5 July 2018

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5 July 2018

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The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

5 July 2018

1 reference

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Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero

5 July 2018

1 reference

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Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities

5 July 2018

1 reference

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Adult-like anti-mycobacterial T cell and in vivo dendritic cell responses following neonatal immunization with Ag85B-ESAT-6 in the IC31 adjuvant

5 July 2018

1 reference

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Delayed maturation of an IL-12-producing dendritic cell subset explains the early Th2 bias in neonatal immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145351

Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor.

5 July 2018

1 reference

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A fundamental role for interleukin-21 in the generation of T follicular helper cells

5 July 2018

1 reference

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Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

5 July 2018

1 reference

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Murine neonates develop vigorous in vivo cytotoxic and Th1/Th2 responses upon exposure to low doses of NIMA-like alloantigens

5 July 2018

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Neonatal B cells suppress innate toll-like receptor immune responses and modulate alloimmunity

5 July 2018

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Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

5 July 2018

1 reference

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IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

5 July 2018

1 reference

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IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

5 July 2018

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Type I interferons protect neonates from acute inflammation through interleukin 10-producing B cells

5 July 2018

1 reference

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Neonatal induction of myelin-specific Th1/Th17 immunity does not result in experimental autoimmune encephalomyelitis and can protect against the disease in adulthood

5 July 2018

1 reference

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Murine neonatal CD4+ cells are poised for rapid Th2 effector-like function

5 July 2018

1 reference

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IL-17 family cytokines and the expanding diversity of effector T cell lineages

5 July 2018

1 reference

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145351

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145351

Transforming growth factor-beta induces development of the T(H)17 lineage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145351

The key regulators of adult T helper cell responses, STAT6 and T-bet, are established in early life in mice

5 July 2018

1 reference

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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

5 July 2018

1 reference

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Preferential production of the IL-12(p40)/IL-23(p19) heterodimer by dendritic cells from human newborns.

5 July 2018

1 reference

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Developmental regulation of Foxp3 expression during ontogeny.

5 July 2018

1 reference

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Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145351

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

5 July 2018

1 reference

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145351

A defect in nucleosome remodeling prevents IL-12(p35) gene transcription in neonatal dendritic cells

5 July 2018

1 reference

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The role of genetic and environmental factors in the development of T-cell mediated allergic disease in early life

5 July 2018

1 reference

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Actively acquired tolerance of foreign cells

5 July 2018

1 reference

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

5 July 2018

1 reference

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CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function

5 July 2018

1 reference

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Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

5 July 2018

1 reference

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CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Enhanced type 1 immunity after secondary viral challenge in mice primed as neonates.

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IL-4 utilizes an alternative receptor to drive apoptosis of Th1 cells and skews neonatal immunity toward Th2.

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21 January 2018

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The human IL-13 locus in neonatal CD4+ T cells is refractory to the acquisition of a repressive chromatin architecture.

21 January 2018

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Th17 alloimmunity prevents neonatal establishment of lymphoid chimerism in IL-4-deprived mice.

21 January 2018

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IL-23 up-regulates IL-10 and induces IL-17 synthesis by polyclonally activated naive T cells in human.

21 January 2018

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Defective TH17 development in human neonatal T cells involves reduced RORC2 mRNA content.

21 January 2018

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21 January 2018

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T regulatory cells contribute to the attenuated primary CD8+ and CD4+ T cell responses to herpes simplex virus type 2 in neonatal mice

21 January 2018

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Plasmodium falciparum infection of the placenta impacts on the T helper type 1 (Th1)/Th2 balance of neonatal T cells through CD4(+)CD25(+) forkhead box P3(+) regulatory T cells and interleukin-10.

21 January 2018

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Developmental exposure to noninherited maternal antigens induces CD4+ T regulatory cells: relevance to mechanism of heart allograft tolerance.

21 January 2018

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Specific maternal microchimeric T cells targeting fetal antigens in β cells predispose to auto-immune diabetes in the child.

21 January 2018

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The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.

21 January 2018

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The 3' enhancer CNS2 is a critical regulator of interleukin-4-mediated humoral immunity in follicular helper T cells.

21 January 2018

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Neonatal follicular Th cell responses are impaired and modulated by IL-4.

21 January 2018

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Environmental and T cell-intrinsic factors limit the expansion of neonatal follicular T helper cells but may be circumvented by specific adjuvants.

21 January 2018

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Notch signaling regulates follicular helper T cell differentiation

21 January 2018

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Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00393

Two independent pathways of maternal cell transmission to offspring: through placenta during pregnancy and by breast-feeding after birth

21 January 2018

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High IL-13 production by human neonatal T cells: neonate immune system regulator?

21 January 2018

1 reference

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CD40 ligation prevents neonatal induction of transplantation tolerance

28 October 2018

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12 December 2020

Tolerance to Noninherited Maternal MHC Antigens in Mice

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12 December 2020

Blocking induction of T helper type 2 responses prevents development of disease in a model of childhood asthma

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12 December 2020

IL-12 prevents neonatal induction of transplantation tolerance in mice

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12 December 2020

Persistence of anti-donor allohelper T cells after neonatal induction of allotolerance in mice

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12 December 2020

Clonal analysis of T cell unresponsiveness to alloantigens induced by neonatal injection of F1 spleen cells into parental mice

1 reference

12 December 2020

Transmission of maternal blood cells to the fetus during pregnancy: detection in mouse neonatal spleen by immunofluorescence flow cytometry and polymerase chain reaction

1 reference

12 December 2020

CD4+CD25+ cells regulate CD8 cell anergy in neonatal tolerant mice

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12 December 2020

Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells

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12 December 2020

"Default" generation of neonatal regulatory T cells

1 reference

12 December 2020

In vivo effects of anti-IL-4 monoclonal antibody on neonatal induction of tolerance and on an associated autoimmune syndrome

1 reference

12 December 2020

IFN-gamma prevents Th2 cell-mediated pathology after neonatal injection of semiallogenic spleen cells in mice

1 reference

12 December 2020

Critical role of interleukin 4 in the induction of neonatal transplantation tolerance

1 reference

12 December 2020

Identifiers

DOI

10.3389/FIMMU.2014.00393

1 reference

31 July 2017

1 reference

31 July 2017

1 reference