Mechanisms of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulation. (Q34093947)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696891%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Mechanisms of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulation (English)

1 reference

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9 February 2020

1 reference

1 reference

4

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9 February 2020

Sohaib A. Khan

10

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9 February 2020

author name string

Santhi D Konduri

1

1 reference

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9 February 2020

Rajesh Medisetty

2

1 reference

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9 February 2020

Wensheng Liu

3

1 reference

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9 February 2020

Pratima Srivastava

5

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9 February 2020

Peter Fritz

7

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9 February 2020

Wendy M Swetzig

8

1 reference

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9 February 2020

Amanda E Gardner

9

1 reference

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9 February 2020

Gokul M Das

11

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9 February 2020

Hiltrud Brauch

6

1 reference

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9 February 2020

language of work or name

English

0 references

publication date

9 August 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696891%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

9 February 2020

published in

1 reference

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9 February 2020

volume

107

1 reference

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9 February 2020

issue

34

1 reference

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9 February 2020

page(s)

15081-15086

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Deregulated estrogen receptor alpha and p53 heterozygosity collaborate in the development of mammary hyperplasia

9 February 2020

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5 July 2018

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5 July 2018

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5 July 2018

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Transcriptional regulation of estrogen receptor-alpha by p53 in human breast cancer cells

5 July 2018

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5 July 2018

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Disruption of estrogen receptor alpha-p53 interaction in breast tumors: a novel mechanism underlying the anti-tumor effect of radiation therapy

5 July 2018

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Transcriptional control of human p53-regulated genes

5 July 2018

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The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

5 July 2018

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Selective estrogen-receptor modulators and antihormonal resistance in breast cancer

5 July 2018

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Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity

5 July 2018

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Estrogen receptor-alpha expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice

5 July 2018

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Estrogen receptor alpha inhibits p53-mediated transcriptional repression: implications for the regulation of apoptosis

5 July 2018

1 reference

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Raloxifene and ICI182,780 increase estrogen receptor-alpha association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12.

5 July 2018

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Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit

5 July 2018

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p53 protein accumulation predicts resistance to endocrine therapy and decreased post-relapse survival in metastatic breast cancer.

5 July 2018

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5 July 2018

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The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer

5 July 2018

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Estrogen receptor-alpha binds p53 tumor suppressor protein directly and represses its function

5 July 2018

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5 July 2018

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Endocrinology and hormone therapy in breast cancer: new insight into estrogen receptor-alpha function and its implication for endocrine therapy resistance in breast cancer

5 July 2018

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An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

5 July 2018

1 reference

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A putative human breast stem cell population is enriched for steroid receptor-positive cells

5 July 2018

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5 July 2018

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Breast cancer, stem/progenitor cells and the estrogen receptor

5 July 2018

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5 July 2018

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The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene.

5 July 2018

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Functional and molecular characterisation of mammary side population cells

5 July 2018

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Connections and regulation of the human estrogen receptor

5 July 2018

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Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population

5 July 2018

1 reference

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Molecular determinants for the tissue specificity of SERMs

5 July 2018

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Combinatorial control of gene expression by nuclear receptors and coregulators

5 July 2018

1 reference

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p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis

5 July 2018

1 reference

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Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

5 July 2018

1 reference

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5 July 2018

Surfing the p53 network

1 reference

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Complete sequencing of TP53 predicts poor response to systemic therapy of advanced breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930589

Histone deacetylases specifically down-regulate p53-dependent gene activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930589

The coregulator exchange in transcriptional functions of nuclear receptors

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930589

5 July 2018

1 reference

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The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells.

5 July 2018

1 reference

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Basal promoter elements as a selective determinant of transcriptional activator function

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1009575107

MicroChIP--a rapid micro chromatin immunoprecipitation assay for small cell samples and biopsies

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1009575107

p53 function is required for hormone-mediated protection of mouse mammary tumorigenesis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930589

Regulation of p53: intricate loops and delicate balances

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930589

RETRACTED: Regulation of p53: intricate loops and delicate balances

28 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1009575107

P53 expression in breast cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20696891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20696891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Estrogen receptor protects p53 from deactivation by human double minute-2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20696891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1009575107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696891%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696891%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference