Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences (Q30493233)

19 October 2017

Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences (English)

1 reference

19 October 2017

1 reference

Daniel Menendez

1

1 reference

19 October 2017

Alberto Inga

series ordinal

2

1 reference

19 October 2017

Michael A Resnick

series ordinal

3

1 reference

19 October 2017

language of work or name

English

0 references

publication date

4 January 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 October 2017

1 reference

19 October 2017

107

1 reference

19 October 2017

4

1 reference

19 October 2017

1500-1505

1 reference

The expanding universe of p53 targets

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

A regulatory loop composed of RAP80-HDM2-p53 provides RAP80-enhanced p53 degradation by HDM2 in response to DNA damage.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Blinded by the Light: The Growing Complexity of p53

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Functional four-base A/T gap core sequence CATTAG of P53 response elements specifically bound tetrameric P53 differently than two-base A/T gap core sequence CATG bound both dimeric and tetrameric P53

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Noncanonical DNA motifs as transactivation targets by wild type and mutant p53

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Characterization of genome-wide p53-binding sites upon stress response.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Transcriptional control of human p53-regulated genes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Structural biology of the tumor suppressor p53.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Mechanisms of regulatory diversity within the p53 transcriptional network

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Functional evolution of the p53 regulatory network through its target response elements

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Interactions of mutant p53 with DNA: guilt by association

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Inactive full-length p53 mutants lacking dominant wild-type p53 inhibition highlight loss of heterozygosity as an important aspect of p53 status in human cancers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

The versatile interactions of p53 with DNA: when flexibility serves specificity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Estrogen receptor-alpha binds p53 tumor suppressor protein directly and represses its function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

A global map of p53 transcription-factor binding sites in the human genome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Transcriptional repression by p53 through direct binding to a novel DNA element

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Definition of a consensus binding site for p53

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA.

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909129107

p53 mutants exhibiting enhanced transcriptional activation and altered promoter selectivity are revealed using a sensitive, yeast-based functional assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909129107

Structural basis of DNA recognition by p53 tetramers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909129107

Penetrance of adrenocortical tumours associated with the germline TP53 R337H mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909129107

p53 domains: identification and characterization of two autonomous DNA-binding regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909129107

Cooperative binding of tetrameric p53 to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909129107

Preferential binding of tumor suppressor p53 to positively or negatively supercoiled DNA involves the C-terminal domain

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Estrogen receptor protects p53 from deactivation by human double minute-2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CA/TG sequence at the 5' end of oligo(A)-tracts strongly modulates DNA curvature

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0909129107

1 reference

19 October 2017

0 references

1 reference

19 October 2017

1 reference