Diverse signalling by 5-hydroxytryptamine (5-HT) receptors (Q34099978)

31 July 2017

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title

Diverse signalling by 5-hydroxytryptamine (5-HT) receptors (English)

1 reference

31 July 2017

Pauwels PJ

1

1 reference

PubMed ID

11108789

31 July 2017

language of work or name

English

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publication date

1 December 2000

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31 July 2017

Biochemical Pharmacology

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31 July 2017

60

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31 July 2017

12

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31 July 2017

1743-1750

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The structure and signalling properties of 5-HT receptors: an endless diversity?

31 July 2017

1 reference

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Agonist-receptor efficacy. II. Agonist trafficking of receptor signals

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7TM receptors: the splicing on the cake

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Genetic Variation in Human 5-HT Receptors: Potential Pathogenetic and Pharmacological Rolea

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G protein-coupled receptors. II. Mechanism of agonist activation.

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Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

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Stimulated [35S]GTP gamma S binding by 5-HT1A receptor agonists in recombinant cell lines. Modulation of apparent efficacy by G-protein activation state

7 January 2021

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Interaction of 5-HT1B/D ligands with recombinant h 5-HT1A receptors: intrinsic activity and modulation by G-protein activation state.

7 January 2021

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5-HT 1B/D receptor antagonists

7 January 2021

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How receptors talk to trimeric G proteins

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Fluorescent labeling of purified beta 2 adrenergic receptor. Evidence for ligand-specific conformational changes

7 January 2021

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Cellular signaling by an agonist-activated receptor/Gs alpha fusion protein

7 January 2021

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GPCR-Galpha fusion proteins: molecular analysis of receptor-G-protein coupling

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Insights into ligand pharmacology using receptor-G-protein fusion proteins

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Quantitative analysis of formyl peptide receptor coupling to g(i)alpha(1), g(i)alpha(2), and g(i)alpha(3).

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Modulation of 5-HT1A receptor signalling by point-mutation of cysteine351 in the rat Galpha(o) protein.

7 January 2021

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Modulation of 5-HT(1A) receptor activation by its interaction with wild-type and mutant g(alphai3) proteins

7 January 2021

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Agonist occupation of an alpha2A-adrenoreceptor-Gi1alpha fusion protein results in activation of both receptor-linked and endogenous Gi proteins. Comparisons of their contributions to GTPase activity and signal transduction and analysis of receptor-

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Ligand-receptor interactions as controlled by wild-type and mutant Thr(370)Lys alpha2B-adrenoceptor-Galpha15 fusion proteins

7 January 2021

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G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C

7 January 2021

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A conserved threonine residue in the second intracellular loop of the 5-hydroxytryptamine 1A receptor directs signaling specificity.

7 January 2021

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Selective coupling of prostaglandin E receptor EP3D to Gi and Gs through interaction of alpha-carboxylic acid of agonist and arginine residue of seventh transmembrane domain

7 January 2021

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Identification of a conserved switch residue responsible for selective constitutive activation of the beta2-adrenergic receptor

7 January 2021

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Up-regulation of a constitutively active form of the beta2-adrenoceptor by sustained treatment with inverse agonists but not antagonists

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Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus.

7 January 2021

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Signal transduction by a 5-HT2 receptor: a mechanistic hypothesis from molecular dynamics simulations of the three-dimensional model of the receptor complexed to ligands

7 January 2021

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Selective activation of inhibitory G-protein alpha-subunits by partial agonists of the human 5-HT1A receptor

7 January 2021

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Hydrophobicity of residue351 of the G protein Gi1 alpha determines the extent of activation by the alpha 2A-adrenoceptor.

7 January 2021

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Four 5-Hydroxytryptamine7 (5-HT7) Receptor Isoforms in Human and Rat Produced by Alternative Splicing: Species Differences Due to Altered Intron-Exon Organization

7 January 2021

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Cloning, expression and pharmacology of the mouse 5-HT(4L) receptor

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Regulation of serotonin-2C receptor G-protein coupling by RNA editing

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7 January 2021

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RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity

7 January 2021

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Serotonin 5-HT2C receptor RNA editing alters receptor basal activity: implications for serotonergic signal transduction

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The activation process of the alpha1B-adrenergic receptor: potential role of protonation and hydrophobicity of a highly conserved aspartate

7 January 2021

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Agonist-Promoted Down-Regulation and Functional Desensitization in Two Naturally Occurring Variants of the Human Serotonin1A Receptor

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Coronary side-effect potential of current and prospective antimigraine drugs

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A naturally occurring amino acid substitution of the human serotonin 5-HT2A receptor influences amplitude and timing of intracellular calcium mobilization

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Serotonin receptor variants in disease: new therapeutic opportunities?

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Agonist-independent activation of Gz by the 5-hydroxytryptamine1A receptor co-expressed in Spodoptera frugiperda cells. Distinguishing inverse agonists from neutral antagonists

7 January 2021

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Inhibition of the constitutive activity of human 5-HT1A receptors by the inverse agonist, spiperone but not the neutral antagonist, WAY 100,635

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Characterisation of a cloned human 5-HT1A receptor cell line using [35S]GTP gamma S binding

7 January 2021

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Functional characterisation of the human cloned 5-HT7 receptor (long form); antagonist profile of SB-258719

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How efficacious are 5-HT1B/D receptor ligands: an answer from GTP gamma S binding studies with stably transfected C6-glial cell lines

7 January 2021

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The 5-HT4 receptor antagonist ML10375 inhibits the constitutive activity of human 5-HT4(c) receptor.

7 January 2021

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Pharmacological characterisation of [35S]-GTPgammaS binding to Chinese hamster ovary cell membranes stably expressing cloned human 5-HT1D receptor subtypes

7 January 2021

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mu-Opioid receptor-stimulated guanosine-5'-O-(gamma-thio)-triphosphate binding in rat thalamus and cultured cell lines: signal transduction mechanisms underlying agonist efficacy

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Activating mutations of the serotonin 5-HT2C receptor

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(00)00476-7

1 reference

31 July 2017

1 reference

PubMed ID

11108789