Janus kinases: components of multiple signaling pathways (Q34103659)

31 July 2017

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title

Janus kinases: components of multiple signaling pathways (English)

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31 July 2017

S G Rane

1

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31 July 2017

E P Reddy

series ordinal

2

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31 July 2017

language of work or name

English

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publication date

1 November 2000

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31 July 2017

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31 July 2017

19

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31 July 2017

5662-5679

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31 July 2017

49

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203925

31 July 2017

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cites work

The Bcl-2 protein family: arbiters of cell survival

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21 January 2018

The Bcl-2 protein family

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Autosomal SCID caused by a point mutation in the N-terminus of Jak3: mapping of the Jak3-receptor interaction domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Activation of the STAT3/acute phase response factor transcription factor by interleukin-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Activation and association of Stat3 with Src in v-Src-transformed cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Malignant transformation of a growth factor-dependent myeloid cell line by Abelson virus without evidence of an autocrine mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The when and how of Src regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Characterization of critical residues in the cytoplasmic domain of the human interleukin-5 receptor alpha chain required for growth signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Jak-STAT signaling induced by the v-abl oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

STATs and gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Characterization of active and inactive forms of the JAK2 protein-tyrosine kinase produced via the baculovirus expression vector system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

A new protein containing an SH2 domain that inhibits JAK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Protein tyrosine phosphatases: a diverse family of intracellular and transmembrane enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

In vitro interaction between STAT 5 and JAK 2; dependence upon phosphorylation status of STAT 5 and JAK 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Involvement of Janus kinases in the insulin signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Role of tyrosine kinases in induction of the c-jun proto-oncogene in irradiated B-lineage lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Cytoplasmic sequences of the growth hormone receptor necessary for signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Mapping of the cytoplasmic domain of the human growth hormone receptor required for the activation of Jak2 and Stat proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4- and IL-13-dependent signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Jaks and Stats in cytokine signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Signaling through the hematopoietic cytokine receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Granulocyte-macrophage colony-stimulating factor provokes RAS activation and transcription of c-fos through different modes of signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The box1 domain of the erythropoietin receptor specifies Janus kinase 2 activation and functions mitogenically within an interleukin 2 beta-receptor chimera

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Isolation and characterization of a new mutant human cell line unresponsive to alpha and beta interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Cytokine signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Jak3 maps to chromosome 8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Other kinases can substitute for Jak2 in signal transduction by interferon-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Critical proline residues of the cytoplasmic domain of the IL-5 receptor alpha chain and its function in IL-5-mediated activation of JAK kinase and STAT5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

A kinase-deficient splice variant of the human JAK3 is expressed in hematopoietic and epithelial cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The molecular basis of X-linked severe combined immunodeficiency: defective cytokine receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Cytokine receptor signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Jaks and STATs: biological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The cytoplasmic domain of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha subunit is essential for both GM-CSF-mediated growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Conditional activation of Janus kinase (JAK) confers factor independence upon interleukin-3-dependent cells. Essential role of Ras in JAK-triggered mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Ras and signal transducer and activator of transcription (STAT) are essential and sufficient downstream components of Janus kinases in cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Negative regulation of cytokine signaling: STAT-induced STAT inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Structure and function of a new STAT-induced STAT inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

An epidermal growth factor receptor/Jak2 tyrosine kinase domain chimera induces tyrosine phosphorylation of Stat5 and transduces a growth signal in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

A membrane-proximal region of the interleukin-2 receptor gamma c chain sufficient for Jak kinase activation and induction of proliferation in T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The human interferon alpha/beta receptor: characterization and molecular cloning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Advances in the understanding of cytokine signal transduction: the role of Jaks and STATs in immunoregulation and the pathogenesis of immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Protein phosphatases in cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Jak2 is essential for signaling through a variety of cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Protein modules and signalling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

A portrait of the Bcl-2 protein family: life, death, and the whole picture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Neoplastic transformation of mast cells by Abelson-MuLV: abrogation of IL-3 dependence by a nonautocrine mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Two members of the JAK family of protein tyrosine kinases map to chromosomes 1p31.3 and 9p24

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct Jak kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Nucleotide sequence of Abelson murine leukemia virus genome: structural similarity of its transforming gene product to other onc gene products with tyrosine-specific kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Double identity for proteins of the Bcl-2 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Genomic sequence, organization, and chromosomal localization of human JAK3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Regulation of the Jak2 tyrosine kinase by its pseudokinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Signal transduction by a CD16/CD7/Jak2 fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The kinase domain of Jak2 mediates induction of bcl-2 and delays cell death in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Interferon gamma activation of Raf-1 is Jak1-dependent and p21ras-independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Cytokines and JAK-STAT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

G-CSF induces tyrosine phosphorylation of the JAK2 protein in the human myeloid G-CSF responsive and proliferative cells, but not in mature neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Interferon-induced nuclear signalling by Jak protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Cytoplasmic domains of the common beta-chain of the GM-CSF/IL-3/IL-5 receptors that are required for inducing differentiation or clonal suppression in myeloid leukaemic cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Identification and sequence of an accessory factor required for activation of the human interferon gamma receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

A family of cytokine-inducible inhibitors of signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Molecular cloning of rat JAK3, a novel member of the JAK family of protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

A critical cytoplasmic domain of the interleukin-5 (IL-5) receptor alpha chain and its function in IL-5-mediated growth signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The conserved box 1 motif of cytokine receptors is required for association with JAK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Expression of Janus kinase 3 in human endothelial and other non-lymphoid and non-myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Activation and inhibition of erythropoietin receptor function: role of receptor dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Switching signals on or off by receptor dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Negative regulation of cytokine signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Molecular characterization of specific interactions between SHP-2 phosphatase and JAK tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The CIS family: negative regulators of JAK-STAT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The CIS/JAB family: novel negative regulators of JAK signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

JAK3 Janus kinase is involved in interleukin 7 signal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

21 January 2018

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Distinct tyrosine phosphorylation sites in JAK3 kinase domain positively and negatively regulate its enzymatic activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

The pathway to signal achievement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

Granulocyte-macrophage colony-stimulating factor-activated signaling pathways in human neutrophils. Involvement of Jak2 in the stimulation of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

The interleukin-5/receptor interaction activates Lyn and Jak2 tyrosine kinases and propagates signals via the Ras-Raf-1-MAP kinase and the Jak-STAT pathways in eosinophils

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Interleukin-3 signals through multiple isoforms of Stat5.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

SHP1 protein tyrosine phosphatase negatively modulates erythroid differentiation and suppression of apoptosis in J2E erythroleukemic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Distribution of the mammalian Stat gene family in mouse chromosomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Identification of JAK protein tyrosine kinases as signaling molecules for prolactin. Functional analysis of prolactin receptor and prolactin-erythropoietin receptor chimera expressed in lymphoid cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Differential effects of prolactin and src/abl kinases on the nuclear translocation of STAT5B and STAT5A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Kinase-deficient forms of Jak1 and Tyk2 inhibit interferon alpha signaling in a dominant manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

An amino acid substitution in the Drosophila hopTum-l Jak kinase causes leukemia-like hematopoietic defects.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Tyrosine phosphorylation of p95Vav in myeloid cells is regulated by GM-CSF, IL-3 and steel factor and is constitutively increased by p210BCR/ABL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 transduce signals through two forms of STAT5.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Defective lymphoid development in mice lacking Jak3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Activation of phosphatidylinositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Oncogenes, growth factors and hematopoietic cell transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor beta and gamma chains.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Cloning members of protein-tyrosine kinase family using polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203925

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203925

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference