Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis (Q24316448)

GOA release 2020-03-11

Janus kinase 2

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GOA release 2020-03-11

M Müller

3

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Klaus Pfeffer

object named as

K Pfeffer

6

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author name string

H Neubauer

1

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A Cumano

2

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H Wu

4

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U Huffstadt

From stem cells to lymphocytes: biology and transplantation

5

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language of work or name

English

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publication date

1 May 1998

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published in

Cell

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volume

93

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page(s)

397-409

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issue

3

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cites work

1 reference

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7 January 2021

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

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7 January 2021

Ligand-induced assembly and activation of the gamma interferon receptor in intact cells

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7 January 2021

JAKs and STATs branch out.

1 reference

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7 January 2021

Activation of JAK2 tyrosine kinase by prolactin receptors in Nb2 cells and mouse mammary gland explants

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7 January 2021

Analysis of gene function in lymphocytes by RAG-2-deficient blastocyst complementation.

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7 January 2021

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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7 January 2021

Requirement for a functional Rb-1 gene in murine development

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7 January 2021

Differentiation and characterization of B-cell precursors detected in the yolk sac and embryo body of embryos beginning at the 10- to 12-somite stage.

1 reference

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7 January 2021

Lymphoid potential, probed before circulation in mouse, is restricted to caudal intraembryonic splanchnopleura.

1 reference

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7 January 2021

STATs and gene regulation

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7 January 2021

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

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7 January 2021

Stat1 associates with c-kit and is activated in response to stem cell factor

1 reference

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7 January 2021

The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl

1 reference

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7 January 2021

Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis

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7 January 2021

Purification of fetal hematopoietic progenitors and demonstration of recombinant multipotential colony-stimulating activity

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7 January 2021

Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors

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7 January 2021

Thrombocytopenia in c-mpl-deficient mice

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7 January 2021

A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

1 reference

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7 January 2021

Cytokine receptor signalling

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7 January 2021

STATs: signal transducers and activators of transcription

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7 January 2021

Jaks and Stats in signaling by the cytokine receptor superfamily

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7 January 2021

Signaling through the hematopoietic cytokine receptors.

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7 January 2021

A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells

1 reference

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7 January 2021

A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.

1 reference

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7 January 2021

IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses.

1 reference

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7 January 2021

Interaction between the components of the interferon gamma receptor complex

1 reference

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7 January 2021

An early pre-liver intraembryonic source of CFU-S in the developing mouse

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7 January 2021

The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells

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7 January 2021

Ontogeny of the Haemopoietic System: Yolk Sac Origin of In Vivo and In Vitro Colony Forming Cells in the Developing Mouse Embryo

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7 January 2021

The Biology of Hematopoietic Stem Cells

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7 January 2021

Production of homozygous mutant ES cells with a single targeting construct

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7 January 2021

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

1 reference

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7 January 2021

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

1 reference

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7 January 2021

Development of hematopoietic stem cell activity in the mouse embryo

1 reference

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7 January 2021

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

1 reference

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7 January 2021

Mice deficient for the IL-3/GM-CSF/IL-5 beta c receptor exhibit lung pathology and impaired immune response, while beta IL3 receptor-deficient mice are normal

1 reference

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7 January 2021

Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice

1 reference

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7 January 2021

Defective lymphoid development in mice lacking Jak3

1 reference

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7 January 2021

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

1 reference

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7 January 2021

Jaks, STATs, cytokine signal transduction, and immunoregulation: are we there yet?

1 reference

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7 January 2021

Jak2 is essential for signaling through a variety of cytokine receptors

1 reference

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7 January 2021

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

1 reference

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7 January 2021

Lymphocyte responses and cytokines

1 reference

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7 January 2021

Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex

1 reference

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7 January 2021

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

1 reference

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7 January 2021

Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

1 reference

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7 January 2021

Characterization of the first definitive hematopoietic stem cells in the AGM and liver of the mouse embryo.

1 reference

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7 January 2021

Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.

1 reference

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7 January 2021

G-CSF induces tyrosine phosphorylation of the JAK2 protein in the human myeloid G-CSF responsive and proliferative cells, but not in mature neutrophils

1 reference

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7 January 2021

Interferon-induced nuclear signalling by Jak protein tyrosine kinases

1 reference

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7 January 2021

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction

1 reference

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7 January 2021

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

Tec kinase associates with c-kit and is tyrosine phosphorylated and activated following stem cell factor binding

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

An early haematopoietic defect in mice lacking the transcription factor GATA-2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

Cytokine receptor signal transduction and the control of hematopoietic cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

Thrombopoietin alone stimulates the early proliferation and survival of human erythroid, myeloid and multipotential progenitors in serum-free culture

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981168-X

7 January 2021

10.1016/S0092-8674(00)81168-X

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

4831572

4831572

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference