Glutamate receptors, neurotoxicity and neurodegeneration (Q34103957)

31 July 2017

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title

Glutamate receptors, neurotoxicity and neurodegeneration (English)

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31 July 2017

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Anthony Lau

1

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PubMed ID

20229265

31 July 2017

Michael Tymianski

series ordinal

2

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31 July 2017

14 March 2010

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31 July 2017

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31 July 2017

460

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31 July 2017

525-542

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31 July 2017

2

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https://scigraph.springernature.com/pub.10.1007/s00424-010-0809-1

31 July 2017

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cites work

Delayed antagonism of calpain reduces excitotoxicity in cultured neurons

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12 December 2020

Immunocytochemical localization of group III metabotropic glutamate receptors in the hippocampus with subtype-specific antibodies

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12 December 2020

Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS

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12 December 2020

Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate

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12 December 2020

Effect of riluzole on focal cerebral ischemia in rats.

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12 December 2020

Glutamate mobilizes [Zn2+] through Ca2+ -dependent reactive oxygen species accumulation.

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12 December 2020

Sensitivity of the developing rat brain to hypobaric/ischemic damage parallels sensitivity to N-methyl-aspartate neurotoxicity

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12 December 2020

The reaction of no with superoxide

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12 December 2020

LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death

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12 December 2020

Reduced neuronal injury after treatment with NG-nitro-L-arginine methyl ester (L-NAME) or 2-sulfo-phenyl-N-tert-butyl nitrone (S-PBN) following experimental brain contusion.

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12 December 2020

The role of NADPH oxidase and neuronal nitric oxide synthase in zinc-induced poly(ADP-ribose) polymerase activation and cell death in cortical culture

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12 December 2020

Anticonvulsant lamotrigine administered on reperfusion fails to improve experimental stroke outcomes

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12 December 2020

Neuroprotective effects of phenyl-t-butyl-nitrone in gerbil global brain ischemia and in cultured rat cerebellar neurons

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12 December 2020

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

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12 December 2020

Nitrosylation. the prototypic redox-based signaling mechanism.

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12 December 2020

Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?

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12 December 2020

Double-blind, randomized, vehicle-controlled study of high-dose tirilazad mesylate in women with aneurysmal subarachnoid hemorrhage. Part I. A cooperative study in Europe, Australia, New Zealand, and South Africa

1 reference

12 December 2020

MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys

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12 December 2020

Presynaptic kainate receptors at hippocampal mossy fiber synapses.

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12 December 2020

Glutamate-based therapeutic approaches: clinical trials with NMDA antagonists

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12 December 2020

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

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12 December 2020

Molecular actions of ebselen--an antiinflammatory antioxidant

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12 December 2020

Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration

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12 December 2020

Manganese superoxide dismutase protects nNOS neurons from NMDA and nitric oxide-mediated neurotoxicity.

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12 December 2020

Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons

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12 December 2020

Dose escalation study of the NMDA glycine-site antagonist licostinel in acute ischemic stroke.

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12 December 2020

Crosstalk between nitric oxide and zinc pathways to neuronal cell death involving mitochondrial dysfunction and p38-activated K+ channels

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12 December 2020

Kainate receptors depress excitatory synaptic transmission at CA3-->CA1 synapses in the hippocampus via a direct presynaptic action.

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12 December 2020

The role of excitatory amino acids and NMDA receptors in traumatic brain injury

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12 December 2020

L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the rat.

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12 December 2020

Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes

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12 December 2020

Inhibition of nitric oxide synthase activity by Zn2+ ion.

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12 December 2020

Ischemia-induced brain damage depends on specific gap-junctional coupling

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12 December 2020

TRPC channels promote cerebellar granule neuron survival.

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12 December 2020

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

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12 December 2020

The toxic effect of sodium L-glutamate on the inner layers of the retina.

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12 December 2020

Kynurenate is neuroprotective following experimental brain injury in the rat

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12 December 2020

Non-NMDA and NMDA receptor-mediated excitotoxic neuronal deaths in adult brain are morphologically distinct: further evidence for an apoptosis-necrosis continuum.

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12 December 2020

Interactions of polyamines with ion channels

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12 December 2020

The molecular basis of NMDA receptor subtypes: native receptor diversity is predicted by subunit composition.

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12 December 2020

Brain lesions in an infant rhesus monkey treated with monsodium glutamate

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12 December 2020

Kinetics of peroxynitrite reaction with amino acids and human serum albumin

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12 December 2020

Modulation of mitochondrial function by endogenous Zn2+ pools.

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12 December 2020

Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein

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12 December 2020

NXY-059 for acute ischemic stroke

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12 December 2020

Ionic dependence of glutamate neurotoxicity

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12 December 2020

Relationship between excitatory amino acid release and outcome after severe human head injury

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12 December 2020

Tirilazad for acute ischaemic stroke

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12 December 2020

A multicenter trial on the efficacy of using tirilazad mesylate in cases of head injury.

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12 December 2020

Formation of S-nitrosothiols via direct nucleophilic nitrosation of thiols by peroxynitrite with elimination of hydrogen peroxide

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12 December 2020

Neuronal vacuolization and necrosis induced by the noncompetitive N-methyl-D-aspartate (NMDA) antagonist MK(+)801 (dizocilpine maleate): a light and electron microscopic evaluation of the rat retrosplenial cortex

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12 December 2020

NXY-059 for the treatment of acute ischemic stroke

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12 December 2020

The role of zinc in selective neuronal death after transient global cerebral ischemia

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12 December 2020

Induction of Neuronal Apoptosis by Thiol Oxidation

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12 December 2020

NMDA-dependent superoxide production and neurotoxicity.

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12 December 2020

Inhibition of caspase-mediated apoptosis by peroxynitrite in traumatic brain injury.

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12 December 2020

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.

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12 December 2020

The action of zinc on synaptic transmission and neuronal excitability in cultures of mouse hippocampus

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12 December 2020

Neuroprotective effect of memantine demonstrated in vivo and in vitro.

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12 December 2020

Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons

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12 December 2020

Effect of the NMDA antagonist MK-801 on local cerebral blood flow in focal cerebral ischaemia in the rat

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12 December 2020

Immunohistochemical localization of metabotropic glutamate receptors, mGluR2 and mGluR3, in rat cerebellar cortex

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12 December 2020

Instrumental role of Na+ in NMDA excitotoxicity in glucose-deprived and depolarized cerebellar granule cells

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12 December 2020

Multiple effects of spermine on N-methyl-D-aspartic acid receptor responses of rat cultured hippocampal neurones.

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12 December 2020

Dynamics of extracellular metabolites in the striatum after middle cerebral artery occlusion in the rat monitored by intracerebral microdialysis.

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12 December 2020

Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluRl, in transfected CHO cells

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12 December 2020

The glutamate AMPA receptor antagonist, YM872, attenuates cortical tissue loss, regional cerebral edema, and neurological motor deficits after experimental brain injury in rats

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12 December 2020

Differential contribution of plasmalemmal Na/Ca exchange isoforms to sodium-dependent calcium influx and NMDA excitotoxicity in depolarized neurons.

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12 December 2020

Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide

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12 December 2020

Riluzole, a novel antiglutamate, prevents memory loss and hippocampal neuronal damage in ischemic gerbils.

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12 December 2020

Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity

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12 December 2020

Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction

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12 December 2020

G-protein-independent signaling mediated by metabotropic glutamate receptors

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12 December 2020

Failure of the competitive N-methyl-D-aspartate antagonist Selfotel (CGS 19755) in the treatment of severe head injury: results of two phase III clinical trials. The Selfotel Investigators.

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12 December 2020

Preferential Zn2+ influx through Ca2+-permeable AMPA/kainate channels triggers prolonged mitochondrial superoxide production

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12 December 2020

Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide

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12 December 2020

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12 December 2020

Ebselen in acute middle cerebral artery occlusion: a placebo-controlled, double-blind clinical trial.

1 reference

12 December 2020

Anti-ischaemic efficacy of a nitric oxide synthase inhibitor and a N-methyl-D-aspartate receptor antagonist in models of transient and permanent focal cerebral ischaemia

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12 December 2020

The neuroprotective efficacy of ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the rat

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12 December 2020

Ischemia induces release of glutamate in regions spared from histopathologic damage in the rat.

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12 December 2020

Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity.

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12 December 2020

Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria

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12 December 2020

LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability

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12 December 2020

Effects of the N-methyl-D-aspartate receptor blocker MK-801 on neurologic function after experimental brain injury

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12 December 2020

Metaanalysis of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage

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12 December 2020

Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose.

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12 December 2020

Antioxidant ebselen reduces oxidative damage in focal cerebral ischemia

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12 December 2020

Dextromethorphan protects against cerebral injury following transient focal ischemia in rabbits

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12 December 2020

Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis

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12 December 2020

Phase II clinical trial of sipatrigine (619C89) by continuous infusion in acute stroke

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12 December 2020

Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide.

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12 December 2020

Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions

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12 December 2020

Nonsteroidal lazaroid U78517F in models of focal and global ischemia.

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12 December 2020

The TRPM7 channel is inactivated by PIP(2) hydrolysis

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12 December 2020

Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats.

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12 December 2020

The polyamine spermine has multiple actions on N-methyl-D-aspartate receptor single-channel currents in cultured cortical neurons

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12 December 2020

In vivo calpain/caspase cross-talk during 3-nitropropionic acid-induced striatal degeneration: implication of a calpain-mediated cleavage of active caspase-3.

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12 December 2020

Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide

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12 December 2020

Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite.

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12 December 2020

Peroxynitrite-mediated protein nitration and lipid peroxidation in a mouse model of traumatic brain injury

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12 December 2020

Regulation of glutamate release by presynaptic kainate receptors in the hippocampus

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12 December 2020

Specific proteolysis of the NR2 subunit at multiple sites by calpain

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12 December 2020

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds

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12 December 2020

Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)

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12 December 2020

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

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12 December 2020

Regulation of N-methyl-D-aspartate receptors by calpain in cortical neurons

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12 December 2020

Translocation of zinc may contribute to seizure-induced death of neurons

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12 December 2020

Apoptosis and necrosis in cerebrovascular disease

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12 December 2020

Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat.

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12 December 2020

Beyond NMDA and AMPA glutamate receptors: emerging mechanisms for ionic imbalance and cell death in stroke

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12 December 2020

Inhibition of nitric oxide synthesis does not reduce infarct volume in a rat model of focal cerebral ischaemia

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12 December 2020

L-arginine decreases infarct size caused by middle cerebral arterial occlusion in SHR

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12 December 2020

Neuronal nitric oxide synthase isoforms alpha and mu are closely related calpain-sensitive proteins.

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12 December 2020

Nitric oxide inhibits caspase activation and apoptotic morphology but does not rescue neuronal death

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12 December 2020

Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury.

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12 December 2020

Global ischemia-induced increases in the gap junctional proteins connexin 32 (Cx32) and Cx36 in hippocampus and enhanced vulnerability of Cx32 knock-out mice.

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12 December 2020

Alterations in metabolism and gap junction expression may determine the role of astrocytes as "good samaritans" or executioners.

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12 December 2020

Functional modification of cytochrome c by peroxynitrite in an electron transfer reaction

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12 December 2020

Zinc-induced neurotoxicity mediated by transient receptor potential melastatin 7 channels

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12 December 2020

Inhibition of nonphosphorylating electron transfer by zinc. The problem of delineating interaction sites.

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12 December 2020

Nitric oxide-induced S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase inhibits enzymatic activity and increases endogenous ADP-ribosylation

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12 December 2020

Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action.

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12 December 2020

Delayed AMPA receptor blockade reduces cerebral infarction induced by focal ischemia

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12 December 2020

Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation

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12 December 2020

Sequestration of glutamate-induced Ca2+ loads by mitochondria in cultured rat hippocampal neurons

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12 December 2020

A critical role of TRPM2 in neuronal cell death by hydrogen peroxide

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12 December 2020

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

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12 December 2020

Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat.

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12 December 2020

Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits

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12 December 2020

Riluzole reduces brain lesions and improves neurological function in rats after a traumatic brain injury.

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12 December 2020

Effects of the nitrone radical scavengers PBN and S-PBN on in vivo trapping of reactive oxygen species after traumatic brain injury in rats

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12 December 2020

Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells

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12 December 2020

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures

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12 December 2020

Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade

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12 December 2020

S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding

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12 December 2020

Inhibition of glutamate-induced delayed calcium deregulation by 2-APB and La3+ in cultured cortical neurones

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12 December 2020

Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate

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12 December 2020

The metabotropic glutamate receptor types 2/3 inhibit L-type calcium channels via a pertussis toxin-sensitive G-protein in cultured cerebellar granule cells

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12 December 2020

Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons

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12 December 2020

Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia

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12 December 2020

Glutamate neurotoxicity in cortical cell culture is calcium dependent

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12 December 2020

S-nitrosation of glutathione by nitric oxide, peroxynitrite, and (*)NO/O(2)(*-).

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12 December 2020

Kainate receptors mediate a slow postsynaptic current in hippocampal CA3 neurons

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12 December 2020

Calpain activation contributes to dendritic remodeling after brief excitotoxic injury in vitro

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12 December 2020

GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation

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12 December 2020

Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4.

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12 December 2020

Neurobiology of zinc and zinc-containing neurons

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12 December 2020

Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia

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12 December 2020

Neuroprotective efficacy of ebselen, an anti-oxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion

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12 December 2020

Accumulation of zinc in degenerating hippocampal neurons of ZnT3-null mice after seizures: evidence against synaptic vesicle origin.

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12 December 2020

Lamotrigine protects hippocampal CA1 neurons from ischemic damage after cardiac arrest.

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12 December 2020

Peroxynitrite causes DNA damage and oxidation of thiols in rat thymocytes [corrected]

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12 December 2020

Selfotel in acute ischemic stroke : possible neurotoxic effects of an NMDA antagonist

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12 December 2020

Cooperative modulation of [3H]MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine, and polyamines

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12 December 2020

Induction and activation by zinc of NADPH oxidase in cultured cortical neurons and astrocytes

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12 December 2020

Inactivation of human manganese-superoxide dismutase by peroxynitrite is caused by exclusive nitration of tyrosine 34 to 3-nitrotyrosine.

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12 December 2020

Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis

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12 December 2020

Zinc neurotoxicity in cortical cell culture

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12 December 2020

Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.

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12 December 2020

Tirilazad reduces cortical infarction after transient but not permanent focal cerebral ischemia in rats

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12 December 2020

Cerebroprotective effect of the nitric oxide synthase inhibitors, 1-(2-trifluoromethylphenyl) imidazole and 7-nitro indazole, after transient focal cerebral ischemia in the rat

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12 December 2020

Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol.

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12 December 2020

Free radical scavenger posttreatment improves functional and morphological outcome after fluid percussion injury in the rat.

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12 December 2020

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

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12 December 2020

Memantine in moderate-to-severe Alzheimer's disease

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12 December 2020

Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activation

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12 December 2020

Inhibition of mitochondrial electron transport by peroxynitrite

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12 December 2020

Zinc-positive boutons in the cerebral cortex of lizards show glutamate immunoreactivity.

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12 December 2020

Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice

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12 December 2020

Aptiganel hydrochloride in acute ischemic stroke: a randomized controlled trial

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12 December 2020

Effects of L-NAME and 7-NI on NOS catalytic activity and behavioral outcome after traumatic brain injury in the rat.

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12 December 2020

Activation of calpain I converts excitotoxic neuron death into a caspase-independent cell death

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12 December 2020

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

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12 December 2020

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

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12 December 2020

Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death

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12 December 2020

Safety, tolerability, and pharmacokinetics of the N-methyl-D-aspartate antagonist dextrorphan in patients with acute stroke. Dextrorphan Study Group

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12 December 2020

Neuroprotection with a calpain inhibitor in a model of focal cerebral ischemia

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12 December 2020

Excitatory amino acids in cerebrospinal fluid following traumatic brain injury in humans.

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12 December 2020

Ischemia opens neuronal gap junction hemichannels.

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12 December 2020

The nitrone free radical scavenger NXY-059 is neuroprotective when administered after traumatic brain injury in the rat.

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12 December 2020

Measurement of intracellular free zinc in living cortical neurons: routes of entry.

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12 December 2020

Double-blind, randomized, vehicle-controlled study of high-dose tirilazad mesylate in women with aneurysmal subarachnoid hemorrhage. Part II. A cooperative study in North America

1 reference

12 December 2020

Isolated cerebral and cerebellar mitochondria produce free radicals when exposed to elevated CA2+ and Na+: implications for neurodegeneration

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12 December 2020

Riluzole attenuates cortical lesion size, but not hippocampal neuronal loss, following traumatic brain injury in the rat.

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12 December 2020

In vitro neurotoxicity of methylisothiazolinone, a commonly used industrial and household biocide, proceeds via a zinc and extracellular signal-regulated kinase mitogen-activated protein kinase-dependent pathway.

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12 December 2020

The synaptic activation of kainate receptors.

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12 December 2020

Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.

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12 December 2020

Role of caspases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons.

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12 December 2020

Brief exposure to zinc is toxic to cortical neurons.

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12 December 2020

Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family.

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12 December 2020

Activation of a caspase 3-related cysteine protease is required for glutamate-mediated apoptosis of cultured cerebellar granule neurons

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12 December 2020

Selective neuron loss after cerebral ischemia in the rat: possible role of transmitter glutamate.

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12 December 2020

Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats

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12 December 2020

Zn2+ inhibits alpha-ketoglutarate-stimulated mitochondrial respiration and the isolated alpha-ketoglutarate dehydrogenase complex

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12 December 2020

Mechanism of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury.

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12 December 2020

Involvement of activated caspase-3-like proteases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons

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12 December 2020

p38 activation is required upstream of potassium current enhancement and caspase cleavage in thiol oxidant-induced neuronal apoptosis

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12 December 2020

Neuroprotective actions of novel and potent ligands of group I and group II metabotropic glutamate receptors

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12 December 2020

Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group

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12 December 2020

Glycine potentiates the NMDA response in cultured mouse brain neurons

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12 December 2020

mu-calpain activation and calpain-mediated cytoskeletal proteolysis following traumatic brain injury.

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12 December 2020

Memantine for dementia

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12 December 2020

Gap-junction-mediated propagation and amplification of cell injury.

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12 December 2020

Identification and characterization of heterogeneous neuronal injury and death in regions of diffuse brain injury: evidence for multiple independent injury phenotypes.

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12 December 2020

The critical role of calpain versus caspase activation in excitotoxic injury induced by nitric oxide

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12 December 2020

Calpain activation is not required for AIF translocation in PARP-1-dependent cell death (parthanatos).

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12 December 2020

Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation

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12 December 2020

Memantine reduces functional and morphological consequences induced by global ischemia in rats.

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12 December 2020

Intra-ischemic extracellular release of dopamine and glutamate is associated with striatal vulnerability to ischemia

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12 December 2020

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

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12 December 2020

The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils

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12 December 2020

SEA0400, a novel and selective inhibitor of the Na+-Ca2+ exchanger, attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models.

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12 December 2020

Blockade of gap junctions in vivo provides neuroprotection after perinatal global ischemia

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12 December 2020

Zinc-induced cortical neuronal death: contribution of energy failure attributable to loss of NAD(+) and inhibition of glycolysis

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12 December 2020

The novel 21-aminosteroid U74006F attenuates cerebral edema and improves survival after brain injury in the rat.

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12 December 2020

Evidence that synaptically-released zinc contributes to neuronal injury after traumatic brain injury

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12 December 2020

Effectiveness of PSD95 inhibitors in permanent and transient focal ischemia in the rat.

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12 December 2020

Effects of lazaroids and a peroxynitrite scavenger in a cell model of peroxynitrite toxicity.

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12 December 2020

Ca2+ permeability of KA-AMPA--gated glutamate receptor channels depends on subunit composition

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12 December 2020

Effects of the 21-aminosteroid U74006F on experimental head injury in mice.

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12 December 2020

Glycine antagonist (gavestinel) in neuroprotection (GAIN International) in patients with acute stroke: a randomised controlled trial. GAIN International Investigators

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12 December 2020

Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia.

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12 December 2020

The Free Radical Trapping Agent N-Tert.-Butyl-α-Phenylnitrone (PBN) Attenuates Cerebral Ischaemic Injury in Gerbils

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12 December 2020

A key role for TRPM7 channels in anoxic neuronal death

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12 December 2020

Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite

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12 December 2020

Molecular characterization of mitochondrial apoptosis-inducing factor

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12 December 2020

Improved therapeutic window for treatment of histotoxic hypoxia with a free radical spin trap

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12 December 2020

Peroxynitrite causes DNA nicks in plasmid pBR322

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12 December 2020

Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death.

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12 December 2020

Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischaemia.

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12 December 2020

YM872, a novel selective alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, reduces brain damage after permanent focal cerebral ischemia in cats.

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12 December 2020

Protective effect of the glutamate antagonist, MK-801 in focal cerebral ischemia in the cat.

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12 December 2020

Reversible inactivation of calpain isoforms by nitric oxide

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12 December 2020

Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury.

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12 December 2020

Glutamate-induced calcium loads: effects on energy metabolism and neuronal viability

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12 December 2020

Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity

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12 December 2020

10.1007/S00424-010-0809-1

Identifiers

DOI

1 reference

PubMed ID

20229265

Dimensions Publication ID

31 July 2017

0 references

1 reference

PubMed ID

20229265