A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development. (Q34111959)

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English	A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development.	scientific article

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scholarly article

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11 March 2020

A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development (English)

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11 March 2020

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based on heuristic

inferred from title

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based on heuristic

inferred from title

serous carcinoma

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based on heuristic

inferred from title

8

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11 March 2020

11

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11 March 2020

author name string

Cheryl A Sherman-Baust

1

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11 March 2020

Elisabetta Kuhn

2

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11 March 2020

Blanca L Valle

3

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11 March 2020

Ie-Ming Shih

4

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11 March 2020

Robert J Kurman

5

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11 March 2020

Tian-Li Wang

6

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11 March 2020

Tomokazu Amano

7

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11 March 2020

Ichiro Miyoshi

9

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11 March 2020

Yoshihiko Araki

10

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11 March 2020

Yongqing Zhang

12

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11 March 2020

Kevin G Becker

13

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11 March 2020

Patrice J Morin

14

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11 March 2020

publication date

1 July 2014

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11 March 2020

Journal of Pathology

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11 March 2020

233

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11 March 2020

3

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11 March 2020

228-237

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11 March 2020

Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

The consequence of oncomorphic TP53 mutations in ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

High-grade serous ovarian cancer arises from fallopian tube in a mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

TP53 mutations in serous tubal intraepithelial carcinoma and concurrent pelvic high-grade serous carcinoma--evidence supporting the clonal relationship of the two lesions

1 reference

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5 July 2018

A comprehensive analysis of PAX8 expression in human epithelial tumors

1 reference

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5 July 2018

Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks

1 reference

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5 July 2018

A Pathologist's Road Map to Benign, Precancerous, and Malignant Intraepithelial Proliferations in the Fallopian Tube

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

Serous tubal intraepithelial carcinoma upregulates markers associated with high-grade serous carcinomas including Rsf-1 (HBXAP), cyclin E and fatty acid synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

Candidate serous cancer precursors in fallopian tube epithelium of BRCA1/2 mutation carriers.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

Evidence for a latent precursor (p53 signature) that may precede serous endometrial intraepithelial carcinoma

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

Serous tubal intraepithelial carcinoma: its potential role in primary peritoneal serous carcinoma and serous cancer prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

A candidate precursor to pelvic serous cancer (p53 signature) and its prevalence in ovaries and fallopian tubes from women with BRCA mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

Pathogenesis of ovarian cancer: lessons from morphology and molecular biology and their clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

Maximizing mouse cancer models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

A candidate precursor to serous carcinoma that originates in the distal fallopian tube.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

PDZ-binding kinase/T-LAK cell-originated protein kinase, a putative cancer/testis antigen with an oncogenic activity in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

Altered expression pattern of topoisomerase IIalpha in ovarian tumor epithelial and stromal cells after platinum-based chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

Technical aspects of immunohistochemistry

1 reference

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5 July 2018

Analysis of microarray data using Z score transformation

1 reference

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5 July 2018

Induction of ovarian cancer by defined multiple genetic changes in a mouse model system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

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5 July 2018

The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: does the emperor have no clothes?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

5 July 2018

The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.4353

21 January 2018

Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.4353

21 January 2018

Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: Evidence for a causal relationship.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.4353

21 January 2018

17beta-estradiol accelerates tumor onset and decreases survival in a transgenic mouse model of ovarian cancer

1 reference

https://api.crossref.org/works/10.1002%2FPATH.4353

21 January 2018

Mouse transgenic for murine oviduct-specific glycoprotein promoter-driven simian virus 40 large T-antigen: tumor formation and its hormonal regulation

1 reference

https://api.crossref.org/works/10.1002%2FPATH.4353

21 January 2018

Serous carcinogenesis in the fallopian tube: a descriptive classification.

1 reference

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21 January 2018

ERBB2 and TOP2A in breast cancer: a comprehensive analysis of gene amplification, RNA levels, and protein expression and their influence on prognosis and prediction.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.4353

21 January 2018

Combined analysis of p53 and RB pathways in epithelial ovarian cancer.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.4353

21 January 2018

Emerging roles for PAX8 in ovarian cancer and endosalpingeal development.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.4353

21 January 2018

Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer

1 reference

https://api.crossref.org/works/10.1002%2FPATH.4353

21 January 2018

Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.

1 reference

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21 January 2018

Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes.

1 reference

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21 January 2018

Prognostic importance of survivin, Ki-67, and topoisomerase IIα in ovarian carcinoma.

1 reference

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21 January 2018

Tight junction proteins claudin-3 and claudin-4 are frequently overexpressed in ovarian cancer but not in ovarian cystadenomas.

1 reference

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28 October 2018

Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

28 October 2018

Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149901

28 October 2018

HER-2 amplification and topoisomerase IIalpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil

1 reference

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28 October 2018

The association between the p53/topoisomerase I and p53/ topoisomerase IIalpha immunophenotypes and the progression of ovarian carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/24652535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The p16-cyclin D1/CDK4-pRb pathway and clinical outcome in epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24652535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The p53 tumor suppressor stimulates the catalytic activity of human topoisomerase IIalpha by enhancing the rate of ATP hydrolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24652535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/PATH.4353

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11 March 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24652535%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

PubMed publication ID

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Europe PubMed Central

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11 March 2020

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