SGLT2 inhibition--a novel strategy for diabetes treatment (Q34117872)

31 July 2017

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title

SGLT2 inhibition--a novel strategy for diabetes treatment (English)

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31 July 2017

Edward C Chao

1

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31 July 2017

Robert R Henry

series ordinal

2

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31 July 2017

publication date

28 May 2010

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Nature Reviews Drug Discovery

31 July 2017

published in

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31 July 2017

volume

9

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31 July 2017

issue

7

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31 July 2017

page(s)

551-559

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Islet beta cell failure in type 2 diabetes

31 July 2017

cites work

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Oral antihyperglycemic therapy for type 2 diabetes: scientific review

31 March 2020

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Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes

31 March 2020

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Effect of diabetes and insulin of the maximum capacity of the renal tubules to reabsorb glucose

31 March 2020

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Sodium glucose co-transporter 2 inhibitors: blocking renal tubular reabsorption of glucose to improve glycaemic control in patients with diabetes

31 March 2020

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Glucose transporters: structure, function and consequences of deficiency

31 March 2020

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The sodium/glucose cotransport family SLC5

31 March 2020

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Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes

31 March 2020

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Renal Na(+)-glucose cotransporters

31 March 2020

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Regulatory mechanisms of Na(+)/glucose cotransporters in renal proximal tubule cells.

31 March 2020

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Inhibition of renal glucose reabsorption: a novel strategy for achieving glucose control in type 2 diabetes mellitus

31 March 2020

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Long-term complications of diabetes mellitus

31 March 2020

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Molecular Analysis of the SGLT2 Gene in Patients with Renal Glucosuria

31 March 2020

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31 March 2020

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Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats

31 March 2020

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Na(+) -glucose transporter-2 messenger ribonucleic acid expression in kidney of diabetic rats correlates with glycemic levels: involvement of hepatocyte nuclear factor-1alpha expression and activity.

31 March 2020

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T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes

31 March 2020

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Multiple-dose pharmacokinetics and pharmacodynamics of sergliflozin etabonate, a novel inhibitor of glucose reabsorption, in healthy overweight and obese subjects: a randomized double-blind study

31 March 2020

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Remogliflozin etabonate, in a novel category of selective low-affinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models

31 March 2020

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Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes

31 March 2020

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Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats

31 March 2020

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Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects

31 March 2020

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Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus

31 March 2020

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Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes

31 March 2020

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A study of dapagliflozin in patients with type 2 diabetes receiving high doses of insulin plus insulin sensitizers: applicability of a novel insulin-independent treatment

31 March 2020

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Novel compound heterozygous mutations in SLC5A2 are responsible for autosomal recessive renal glucosuria

31 March 2020

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Autosomal recessive renal glucosuria attributable to a mutation in the sodium glucose cotransporter (SGLT2)

31 March 2020

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Renal sodium-glucose transport: role in diabetes mellitus and potential clinical implications

31 March 2020

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Human cardiomyocytes express high level of Na+/glucose cotransporter 1 (SGLT1)

31 March 2020

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I. Glucose galactose malabsorption.

31 March 2020

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Discovery of canagliflozin, a novel C-glucoside with thiophene ring, as sodium-dependent glucose cotransporter 2 inhibitor for the treatment of type 2 diabetes mellitus.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20508640

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Glucotoxicity and beta-cell failure in type 2 diabetes mellitus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20508640

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRD3180

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Dimensions Publication ID

31 July 2017

1035063099

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