Complementary roles for exonuclease 1 and Flap endonuclease 1 in maintenance of triplet repeats (Q34121171)

31 July 2017

title

Complementary roles for exonuclease 1 and Flap endonuclease 1 in maintenance of triplet repeats (English)

1 reference

31 July 2017

Aarthy C Vallur

1

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31 July 2017

Nancy Maizels

series ordinal

2

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31 July 2017

language of work or name

English

0 references

publication date

19 July 2010

1 reference

Journal of Biological Chemistry

31 July 2017

published in

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31 July 2017

volume

285

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31 July 2017

issue

37

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31 July 2017

page(s)

28514-28519

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describes a project that uses

31 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2937877/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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R loops stimulate genetic instability of CTG.CAG repeats

5 July 2018

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Incision-dependent and error-free repair of (CAG)(n)/(CTG)(n) hairpins in human cell extracts

5 July 2018

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The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo

5 July 2018

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Replisome stalling and stabilization at CGG repeats, which are responsible for chromosomal fragility

5 July 2018

1 reference

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FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts

5 July 2018

1 reference

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Transcription destabilizes triplet repeats

5 July 2018

1 reference

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Activities of human exonuclease 1 that promote cleavage of transcribed immunoglobulin switch regions

5 July 2018

1 reference

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Trinucleotide Repeat Disorders

5 July 2018

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Haploinsufficiency of yeast FEN1 causes instability of expanded CAG/CTG tracts in a length-dependent manner

5 July 2018

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Postreplication repair inhibits CAG.CTG repeat expansions in Saccharomyces cerevisiae.

5 July 2018

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Transcription promotes contraction of CAG repeat tracts in human cells

5 July 2018

1 reference

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Flap endonuclease 1: a central component of DNA metabolism

5 July 2018

1 reference

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Mutations in Yeast Replication Proteins That Increase CAG/CTG Expansions Also Increase Repeat Fragility

5 July 2018

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Complementary functions of the Saccharomyces cerevisiae Rad2 family nucleases in Okazaki fragment maturation, mutation avoidance, and chromosome stability

5 July 2018

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Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage

5 July 2018

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Molecular interactions of human Exo1 with DNA

5 July 2018

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Structural features of trinucleotide repeats associated with DNA expansion

5 July 2018

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Microsatellites in different eukaryotic genomes: survey and analysis

5 July 2018

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The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities

5 July 2018

1 reference

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CGG/CCG repeats exhibit orientation-dependent instability and orientation-independent fragility in Saccharomyces cerevisiae

5 July 2018

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Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism

5 July 2018

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The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs

5 July 2018

1 reference

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DNA secondary structure: a common and causative factor for expansion in human disease

5 July 2018

1 reference

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Triplet repeats form secondary structures that escape DNA repair in yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937877

Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1

5 July 2018

1 reference

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Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2

5 July 2018

1 reference

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Mechanism of tracking and cleavage of adduct-damaged DNA substrates by the mammalian 5'- to 3'-exonuclease/endonuclease RAD2 homologue 1 or flap endonuclease 1.

5 July 2018

1 reference

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Calf 5' to 3' exo/endonuclease must slide from a 5' end of the substrate to perform structure-specific cleavage

5 July 2018

1 reference

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The fragile X syndrome d(CGG)n nucleotide repeats form a stable tetrahelical structure

5 July 2018

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Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937877

Stimulation of eukaryotic flap endonuclease-1 activities by proliferating cell nuclear antigen (PCNA) is independent of its in vitro interaction via a consensus PCNA binding region

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.132738

Human FEN-1 can process the 5'-flap DNA of CTG/CAG triplet repeat derived from human genetic diseases by length and sequence dependent manner.

21 January 2018

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Analysis of human flap endonuclease 1 mutants reveals a mechanism to prevent triplet repeat expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.132738

Concerted action of exonuclease and Gap-dependent endonuclease activities of FEN-1 contributes to the resolution of triplet repeat sequences (CTG)n- and (GAA)n-derived secondary structures formed during maturation of Okazaki fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.132738

Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion

21 January 2018

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12 December 2020

Expansion and length-dependent fragility of CTG repeats in yeast

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12 December 2020

The Bloom's syndrome helicase unwinds G4 DNA

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12 December 2020

Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n

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12 December 2020

Identifiers

DOI

10.1074/JBC.M110.132738

1 reference

31 July 2017

1 reference

31 July 2017

1 reference