TWEAK causes myotube atrophy through coordinated activation of ubiquitin-proteasome system, autophagy, and caspases. (Q34132291)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21567392%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

TWEAK causes myotube atrophy through coordinated activation of ubiquitin-proteasome system, autophagy, and caspases (English)

1 reference

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ubiquitin-proteasome system

31 January 2020

main subject

autophagy

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0 references

author

Ashwani Mittal

2

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31 January 2020

Ashok Kumar

4

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31 January 2020

author name string

Shephali Bhatnagar

1

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31 January 2020

Sanjay K Gupta

3

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31 January 2020

publication date

1 March 2012

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Journal of Cellular Physiology

31 January 2020

published in

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31 January 2020

volume

227

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31 January 2020

issue

3

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31 January 2020

page(s)

1042-1051

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Mitochondrial fission and remodelling contributes to muscle atrophy.

31 January 2020

cites work

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Signaling pathways perturbing muscle mass

5 July 2018

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The TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice.

5 July 2018

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The IKK complex contributes to the induction of autophagy

5 July 2018

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p38 Mitogen-activated protein kinase modulates endotoxin-induced diaphragm caspase activation

5 July 2018

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The JNK MAP kinase pathway contributes to the development of endotoxin-induced diaphragm caspase activation

5 July 2018

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During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Autophagy fights disease through cellular self-digestion

5 July 2018

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Autophagy in the Pathogenesis of Disease

5 July 2018

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FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells

5 July 2018

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FoxO3 controls autophagy in skeletal muscle in vivo

5 July 2018

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The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle

5 July 2018

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Fibroblast growth factor inducible 14 (Fn14) is required for the expression of myogenic regulatory factors and differentiation of myoblasts into myotubes. Evidence for TWEAK-independent functions of Fn14 during myogenesis

5 July 2018

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Cancer cachexia signaling pathways continue to emerge yet much still points to the proteasome

5 July 2018

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5 July 2018

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Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration

5 July 2018

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Caspases in cell survival, proliferation and differentiation.

5 July 2018

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Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein.

5 July 2018

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TWEAK attenuates the transition from innate to adaptive immunity

5 July 2018

1 reference

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Ubiquitin-protein ligases in muscle wasting

5 July 2018

1 reference

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Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I

5 July 2018

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Disruption of either the Nfkb1 or the Bcl3 gene inhibits skeletal muscle atrophy

5 July 2018

1 reference

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Degradation of MyoD mediated by the SCF (MAFbx) ubiquitin ligase

5 July 2018

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IKKbeta/NF-kappaB activation causes severe muscle wasting in mice

5 July 2018

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5 July 2018

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Cancer cachexia is regulated by selective targeting of skeletal muscle gene products

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions

5 July 2018

1 reference

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TNF-alpha increases ubiquitin-conjugating activity in skeletal muscle by up-regulating UbcH2/E220k

5 July 2018

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Tumor necrosis factor-regulated biphasic activation of NF-kappa B is required for cytokine-induced loss of skeletal muscle gene products

5 July 2018

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5 July 2018

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Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

5 July 2018

1 reference

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Identification of ubiquitin ligases required for skeletal muscle atrophy

5 July 2018

1 reference

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Induction of autophagy and inhibition of tumorigenesis by beclin 1

5 July 2018

1 reference

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3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

5 July 2018

1 reference

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Autophagy is required to maintain muscle mass.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154369

Absence of caspase-3 protects against denervation-induced skeletal muscle atrophy.

28 October 2018

1 reference

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Downstream of Akt: FoxO3 and mTOR in the regulation of autophagy in skeletal muscle

28 October 2018

1 reference

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Expression of a calpastatin transgene slows muscle wasting and obviates changes in myosin isoform expression during murine muscle disuse

28 October 2018

1 reference

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The role of cytokines in cancer cachexia

28 October 2018

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12 December 2020

Glucocorticoids induce proteasome C3 subunit expression in L6 muscle cells by opposing the suppression of its transcription by NF-kappa B

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12 December 2020

Importance of the ATP-ubiquitin-proteasome pathway in the degradation of soluble and myofibrillar proteins in rabbit muscle extracts

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12 December 2020

The pivotal role of cytokines in muscle wasting during cancer

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12 December 2020

Elevated caspase and AIF gene expression correlate with progression of sarcopenia during aging in male F344BN rats

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12 December 2020

FoxO3 controls dangerous proteolytic liaisons

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12 December 2020

Identifiers

DOI

10.1002/JCP.22821

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21567392%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21567392%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PubMed publication ID

21567392

1 reference