TNF-related weak inducer of apoptosis (TWEAK) is a potent skeletal muscle-wasting cytokine (Q34132318)

31 July 2017

TNF-related weak inducer of apoptosis (TWEAK) is a potent skeletal muscle-wasting cytokine (English)

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31 July 2017

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Harish Changotra

2

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Ashok Kumar

object named as

Ashok Kumar

6

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author name string

Charu Dogra

1

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31 July 2017

Nia Wedhas

3

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31 July 2017

Xuezhong Qin

4

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31 July 2017

Jon E Wergedal

5

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31 July 2017

language of work or name

English

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publication date

21 February 2007

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31 July 2017

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31 July 2017

21

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31 July 2017

1857-1869

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31 July 2017

8

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describes a project that uses

31 July 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4154373/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein.

1 reference

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TWEAK attenuates the transition from innate to adaptive immunity

5 July 2018

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Inhibition of mechanosensitive cation channels inhibits myogenic differentiation by suppressing the expression of myogenic regulatory factors and caspase-3 activity

5 July 2018

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Ubiquitin-protein ligases in muscle wasting

5 July 2018

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Molecular determinants of skeletal muscle mass: getting the "AKT" together

5 July 2018

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Pregnancy-associated plasma protein-A regulates myoblast proliferation and differentiation through an insulin-like growth factor-dependent mechanism

5 July 2018

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TWEAK induces liver progenitor cell proliferation

5 July 2018

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Response of the ubiquitin-proteasome pathway to changes in muscle activity

5 July 2018

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The pivotal role of cytokines in muscle wasting during cancer.

5 July 2018

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Molecular signaling pathways regulating muscle proteolysis during atrophy

5 July 2018

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Pathophysiology of peripheral muscle wasting in cardiac cachexia

5 July 2018

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Soluble tumor necrosis factor-like weak inducer of apoptosis overexpression in HEK293 cells promotes tumor growth and angiogenesis in athymic nude mice.

5 July 2018

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Disruption of either the Nfkb1 or the Bcl3 gene inhibits skeletal muscle atrophy

5 July 2018

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IL-6-induced skeletal muscle atrophy

5 July 2018

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IKKbeta/NF-kappaB activation causes severe muscle wasting in mice

5 July 2018

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The molecular basis of skeletal muscle atrophy

5 July 2018

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Cancer cachexia is regulated by selective targeting of skeletal muscle gene products

5 July 2018

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Nuclear factor-kappaB: its role in health and disease

5 July 2018

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Functional expression of TWEAK in human hepatocellular carcinoma: possible implication in cell proliferation and tumor angiogenesis

5 July 2018

1 reference

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The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

5 July 2018

1 reference

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TWEAK/Fn14 interaction stimulates human bronchial epithelial cells to produce IL-8 and GM-CSF.

5 July 2018

1 reference

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Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

5 July 2018

1 reference

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Proinflammatory cytokines and skeletal muscle

5 July 2018

1 reference

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TWEAK can induce pro-inflammatory cytokines and matrix metalloproteinase-9 in macrophages

5 July 2018

1 reference

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Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

5 July 2018

1 reference

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TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor

5 July 2018

1 reference

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TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.

5 July 2018

1 reference

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TNF-alpha increases ubiquitin-conjugating activity in skeletal muscle by up-regulating UbcH2/E220k

5 July 2018

1 reference

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Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death

5 July 2018

1 reference

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ADAM12 alleviates the skeletal muscle pathology in mdx dystrophic mice

5 July 2018

1 reference

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Cytokines, apoptosis and cachexia: the potential for TNF antagonism

5 July 2018

1 reference

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A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification

5 July 2018

1 reference

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Alterations in TNF- and IL-related gene expression in space-flown WI38 human fibroblasts

5 July 2018

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Activation of an alternative NF-kappaB pathway in skeletal muscle during disuse atrophy

5 July 2018

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The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

5 July 2018

1 reference

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Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Tumor necrosis factor-alpha and muscle wasting: a cellular perspective

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Identification of ubiquitin ligases required for skeletal muscle atrophy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kappaB.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

NF-kappaB mediates the protein loss induced by TNF-alpha in differentiated skeletal muscle myotubes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Ubiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Signal transduction pathways that regulate eukaryotic protein synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Glycogen synthase kinase-3 is the predominant insulin-regulated eukaryotic initiation factor 2B kinase in skeletal muscle.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

TWEAK induces angiogenesis and proliferation of endothelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-kappaB activation in response to tumor necrosis factor alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Identification of a ligand for the death-domain-containing receptor Apo3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

A simplified system for generating recombinant adenoviruses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

The proteasome: paradigm of a self-compartmentalizing protease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Control of the translational regulators PHAS-I and PHAS-II by insulin and cAMP in 3T3-L1 adipocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Tumor necrosis factor, other cytokines and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Tumor necrosis factor inhibits human myogenesis in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Regulation of phosphatidylinositol 3-kinase (PI3K)/Akt and nuclear factor-kappa B signaling pathways in dystrophin-deficient skeletal muscle in response to mechanical stretch.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Functional expression of TWEAK in human colonic adenocarcinoma cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

IL-1beta impairs insulin-like growth factor i-induced differentiation and downstream activation signals of the insulin-like growth factor i receptor in myoblasts.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Two pathways to NF-kappaB.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154373

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis-Induced Neurodegeneration

28 October 2018

1 reference

12 December 2020

Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states

1 reference

12 December 2020

TWEAK is a novel arthritogenic mediator

1 reference

12 December 2020

Glucocorticoids induce proteasome C3 subunit expression in L6 muscle cells by opposing the suppression of its transcription by NF-kappa B

1 reference

12 December 2020

TWEAK stimulation of astrocytes and the proinflammatory consequences

1 reference

12 December 2020

TWEAK is expressed by glial cells, induces astrocyte proliferation and increases EAE severity

1 reference

12 December 2020

Identifiers

DOI

10.1096/FJ.06-7537COM

1 reference

31 July 2017

1 reference

31 July 2017

1 reference