Ubiquitination of lysine-331 by Kaposi's sarcoma-associated herpesvirus protein K5 targets HFE for lysosomal degradation (Q34136411)

31 July 2017

title

Ubiquitination of lysine-331 by Kaposi's sarcoma-associated herpesvirus protein K5 targets HFE for lysosomal degradation (English)

1 reference

31 July 2017

main subject

protein ubiquitination

1 reference

5

John Trowsdale

1 reference

31 July 2017

David A Rhodes

1

1 reference

31 July 2017

Louise H Boyle

series ordinal

2

1 reference

31 July 2017

Jessica M Boname

series ordinal

3

1 reference

31 July 2017

Paul J Lehner

series ordinal

4

1 reference

31 July 2017

language of work or name

English

0 references

publication date

30 August 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

published in

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31 July 2017

volume

107

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31 July 2017

issue

37

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31 July 2017

page(s)

16240-16245

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Efficient internalization of MHC I requires lysine-11 and lysine-63 mixed linkage polyubiquitin chains.

31 July 2017

cites work

1 reference

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Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression

5 July 2018

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Viral infection and iron metabolism

5 July 2018

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The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression

5 July 2018

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ESCRT complexes and the biogenesis of multivesicular bodies

5 July 2018

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Localisation of proteins of iron metabolism in the human placenta and liver.

5 July 2018

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The role of iron regulatory proteins in mammalian iron homeostasis and disease

5 July 2018

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A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

5 July 2018

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Iron and microbial infection

5 July 2018

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The hereditary hemochromatosis protein, HFE, lowers intracellular iron levels independently of transferrin receptor 1 in TRVb cells

5 July 2018

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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

5 July 2018

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Membrane traffic: GGAs sort ubiquitin

5 July 2018

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Balancing acts: molecular control of mammalian iron metabolism

5 July 2018

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Expression of the hereditary hemochromatosis protein HFE increases ferritin levels by inhibiting iron export in HT29 cells

5 July 2018

1 reference

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Iron: a target for the management of Kaposi's sarcoma?

5 July 2018

1 reference

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Mechanisms of HFE-induced regulation of iron homeostasis: Insights from the W81A HFE mutation

5 July 2018

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The hemochromatosis protein HFE inhibits iron export from macrophages.

5 July 2018

1 reference

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Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation

5 July 2018

1 reference

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Hepcidin, a urinary antimicrobial peptide synthesized in the liver

5 July 2018

1 reference

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Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis

5 July 2018

1 reference

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HFE downregulates iron uptake from transferrin and induces iron-regulatory protein activity in stably transfected cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941293

The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells

5 July 2018

1 reference

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Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum

5 July 2018

1 reference

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Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor

5 July 2018

1 reference

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Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941293

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

5 July 2018

1 reference

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Endemic Kaposi's sarcoma in Africa and local volcanic soils

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941293

HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003421107

Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003421107

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003421107

Human herpesvirus 8 and iron staining are useful in differentiating Kaposi sarcoma from interstitial granuloma annulare

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003421107

Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003421107

High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003421107

Immune evasion by Kaposi's sarcoma-associated herpesvirus

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20805500

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1003421107

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference