A fluopol-ABPP HTS assay to identify PAD inhibitors (Q34143238)

31 July 2017

title

A fluopol-ABPP HTS assay to identify PAD inhibitors (English)

1 reference

31 July 2017

8

Benjamin F Cravatt

1 reference

31 July 2017

1

Bryan Knuckley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20740228

23 June 2024

author name string

Jessica Slack

4

1 reference

31 July 2017

Hugh Rosen

7

1 reference

31 July 2017

Justin E. Jones

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20740228

23 June 2024

Daniel A. Bachovchin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20740228

23 June 2024

Corey P. Causey

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20740228

23 June 2024

Steven J. Brown

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20740228

23 June 2024

Benjamin F. Cravatt

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20740228

23 June 2024

Paul R. Thompson

9

1 reference

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23 June 2024

language of work or name

English

0 references

publication date

25 August 2010

1 reference

full work available at URL

31 July 2017

https://europepmc.org/articles/pmc2943038?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20740228

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20740228/?tool=EBI

23 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20740228

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20740228/pdf/?tool=EBI

23 June 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20740228

https://europepmc.org/articles/PMC2943038

23 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20740228

https://europepmc.org/articles/PMC2943038?pdf=render

23 June 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20740228

https://doi.org/10.1039/c0cc02634d

23 June 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20740228

23 June 2024

published in

Chemical Communications

1 reference

31 July 2017

volume

46

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31 July 2017

issue

38

1 reference

31 July 2017

page(s)

7175-7177

1 reference

Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3.

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

Haloacetamidine-based inactivators of protein arginine deiminase 4 (PAD4): evidence that general acid catalysis promotes efficient inactivation

5 July 2018

1 reference

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Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential

5 July 2018

1 reference

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Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

Increased PADI4 expression in blood and tissues of patients with malignant tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

Regulation of p53 target gene expression by peptidylarginine deiminase 4

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis

5 July 2018

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Activity-based protein profiling: from enzyme chemistry to proteomic chemistry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

Histone deimination as a response to inflammatory stimuli in neutrophils.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

Protein arginine deiminase 4: evidence for a reverse protonation mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

Activity-based protein profiling reagents for protein arginine deiminase 4 (PAD4): synthesis and in vitro evaluation of a fluorescently labeled probe

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

A fluoroacetamidine-based inactivator of protein arginine deiminase 4: design, synthesis, and in vitro and in vivo evaluation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

Genotoxicity of streptonigrin: a review

5 July 2018

1 reference

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Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases.

5 July 2018

1 reference

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Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumor quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943038

The effects of streptonigrin on experimental tumors

28 October 2018

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12 December 2020

Transplantable human tumors in experimental chemotherapy: effects of streptonigrin on HS No. 1 and HEp No. 3 in the rat

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Preliminary observations on the use of streptonigrin as an antitumor agent in human beings

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A colorimetric 96-well microtiter plate assay for the determination of enzymatically formed citrulline

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An antitumor spectrum of streptonigrin

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Identifiers

DOI

10.1039/C0CC02634D

1 reference

31 July 2017

1 reference

31 July 2017

1 reference