A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome (Q34145335)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132179%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome (English)

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12 March 2020

1

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12 March 2020

C Axel Innis

series ordinal

3

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12 March 2020

author name string

Thomas A Steitz

series ordinal

2

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12 March 2020

publication date

17 August 2014

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Nature Structural & Molecular Biology

12 March 2020

published in

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12 March 2020

volume

21

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12 March 2020

issue

9

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12 March 2020

page(s)

787-793

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How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis

12 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

The 2'-OH group of the peptidyl-tRNA stabilizes an active conformation of the ribosomal PTC.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

Theory of coupled electron and proton transfer reactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

The crystal structure of unmodified tRNAPhe from Escherichia coli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

PHENIX: a comprehensive Python-based system for macromolecular structure solution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

The transition state for peptide bond formation reveals the ribosome as a water trap

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

Phasercrystallographic software

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

An uncharged amine in the transition state of the ribosomal peptidyl transfer reaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

Crystal structure of a 70S ribosome-tRNA complex reveals functional interactions and rearrangements

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

Structure of the 70S ribosome complexed with mRNA and tRNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

A protein component at the heart of an RNA machine: the importance of protein l27 for the function of the bacterial ribosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

Coot: model-building tools for molecular graphics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

The structural basis of ribosome activity in peptide bond synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

In vivo deuteration of transfer RNAs: overexpression and large-scale purification of deuterated specific tRNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

Synthesis and Aminoacylation of 3′-Amino-3′-deoxy Transfer RNA and Its Activity in Ribosomal Protein Synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

Molecular mechanisms for proton transport in membranes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156881

Structural insights into the roles of water and the 2' hydroxyl of the P site tRNA in the peptidyl transferase reaction

5 July 2018

1 reference

Role of ribosomal protein L27 in peptidyl transfer

21 January 2018

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Important contribution to catalysis of peptide bond formation by a single ionizing group within the ribosome.

21 January 2018

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Different substrate-dependent transition states in the active site of the ribosome.

21 January 2018

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A two-step chemical mechanism for ribosome-catalysed peptide bond formation

21 January 2018

1 reference

Peptide-bond synthesis on the ribosome: no free vicinal hydroxy group required on the terminal ribose residue of peptidyl-tRNA.

21 January 2018

1 reference

The role of 23S ribosomal RNA residue A2451 in peptide bond synthesis revealed by atomic mutagenesis.

21 January 2018

1 reference

Substrate-assisted catalysis of peptide bond formation by the ribosome

21 January 2018

1 reference

The active site of the ribosome is composed of two layers of conserved nucleotides with distinct roles in peptide bond formation and peptide release

21 January 2018

1 reference

The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination.

21 January 2018

1 reference

Efficient Ribosomal Peptidyl Transfer Critically Relies on the Presence of the Ribose 2‘-OH at A2451 of 23S rRNA

21 January 2018

1 reference

Minimal transition state charge stabilization of the oxyanion during peptide bond formation by the ribosome

21 January 2018

1 reference

Peptide bond formation on the ribosome: the role of the 2'-OH group on the terminal adenosine of peptidyl-tRNA and of the length of nascent peptide chain

31 March 2020

1 reference

Peptide bond formation does not involve acid-base catalysis by ribosomal residues

31 March 2020

1 reference

Mutational analysis of the ribosomal protein Rpl10 from yeast

31 March 2020

1 reference

Crystallization and preliminary X-ray analysis of Escherichia coli methionyl-tRNAMet(f) formyltransferase complexed with formyl-methionyl-tRNAMet(f)

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.2871

1 reference

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12 March 2020

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12 March 2020

PubMed publication ID

25132179

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132179%20AND%20SRC:MED&resulttype=core&format=json