Tumor suppressor activity of AP2alpha mediated through a direct interaction with p53. (Q34149151)

31 July 2017

Tumor suppressor activity of AP2alpha mediated through a direct interaction with p53. (English)

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31 July 2017

Lisa A McPherson

1

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31 July 2017

Alexander V Loktev

series ordinal

2

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31 July 2017

Ronald J Weigel

series ordinal

3

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31 July 2017

language of work or name

English

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publication date

10 September 2002

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Journal of Biological Chemistry

31 July 2017

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31 July 2017

277

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31 July 2017

47

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31 July 2017

45028-45033

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Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements

31 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Cloning and characterization of a novel mouse AP-2 transcription factor, AP-2delta, with unique DNA binding and transactivation properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor AP-2beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

AP-2alpha transcription factor is required for early morphogenesis of the lens vesicle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Gene regulation in melanoma progression by the AP-2 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

AP-2 family members regulate basal and cAMP-induced expression of human chorionic gonadotropin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

The developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Transcriptional regulation of estrogen receptor in breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Identification of ERF-1 as a member of the AP2 transcription factor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Immunohistochemical analysis reveals a tumour suppressor-like role for the transcription factor AP-2 in invasive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Expression of transcription factor AP-2 in colorectal adenomas and adenocarcinomas; comparison of immunohistochemistry and in situ hybridisation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Downregulation of transcription factor AP-2 predicts poor survival in stage I cutaneous malignant melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Role of AP-2 in tumor growth and metastasis of human melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

p22/WAF1 expression in human colorectal carcinoma: association with p53, transcription factor AP-2 and prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

AP2alpha and AP2gamma: a comparison of binding site specificity and trans-activation of the estrogen receptor promoter and single site promoter constructs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Genomic structure of the promoters of the human estrogen receptor-alpha gene demonstrate changes in chromatin structure induced by AP2gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Kinetics of p53 binding to promoter sites in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Ligand-dependent interaction of estrogen receptor-alpha with members of the forkhead transcription factor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Radiation-induced cell cycle arrest compromised by p21 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Sequence-specific transcriptional activation is essential for growth suppression by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

A simple p53 functional assay for screening cell lines, blood, and tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Identification and classification of p53-regulated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

p53 expression in human breast cancer related to survival and prognostic factors: an immunohistochemical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Nuclear p53 Immunoreaction Associated with Poor Prognosis of Breast Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Accumulation of p53 Tumor Suppressor Gene Protein: An Independent Marker of Prognosis in Breast Cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

p53 protein expression in human breast carcinoma: relationship to expression of epidermal growth factor receptor, c-erbB-2 protein overexpression, and oestrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Cellular accumulation of p53 protein: an independent prognostic factor in stage II breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

p53 quantitative immunocytochemical analysis in breast carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Cofactor competition between the ligand-bound oestrogen receptor and an intron 1 enhancer leads to oestrogen repression of ERBB2 expression in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

p53 transformation-related protein: detection of an associated phosphotransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Detection of a common feature in several human tumor cell lines--a 53,000-dalton protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Adenovirus serotype determines association and localization of the large E1B tumor antigen with cellular tumor antigen p53 in transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Dominant-negative transcription factor AP-2 augments SB-2 melanoma tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

The p53 tumor suppressor gene: from molecular biology to clinical investigation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Expression of AP-2 transcription factor and of its downstream target genes c-kit, E-cadherin and p21 in human cutaneous melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

P53 expression in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

p53 and c-erbB-2 protein expression in breast carcinomas. An immunohistochemical study including correlations with receptor status, proliferation markers, and clinical stage in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Relationship between p53 expression and other prognostic factors in human breast carcinoma. An immunohistochemical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

Prognostic value of p53 in breast invasive ductal carcinoma: an immunohistochemical study on 942 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

AP-2 transcription factors in the regulation of ERBB2 gene transcription by oestrogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208924200

21 January 2018

Identifiers

DOI

10.1074/JBC.M208924200

1 reference

31 July 2017

1 reference