Mitochondrial aldehyde dehydrogenase mediates vasodilator responses of glyceryl trinitrate and sodium nitrite in the pulmonary vascular bed of the rat (Q34150559)

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English	Mitochondrial aldehyde dehydrogenase mediates vasodilator responses of glyceryl trinitrate and sodium nitrite in the pulmonary vascular bed of the rat	scientific article

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scholarly article

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5 February 2020

Mitochondrial aldehyde dehydrogenase mediates vasodilator responses of glyceryl trinitrate and sodium nitrite in the pulmonary vascular bed of the rat (English)

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5 February 2020

pharmaceutical preparation of nitroglycerin

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Edward A Pankey

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5 February 2020

Philip J. Kadowitz

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Philip J Kadowitz

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5 February 2020

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Bobby D Nossaman

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5 February 2020

Subramanyam N Murthy

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Subramanyam N Murthy

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5 February 2020

Adeleke M Badejo

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Adeleke M Badejo

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5 February 2020

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Chris Hodnette

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5 February 2020

Jasdeep S Dhaliwal

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5 February 2020

David B Casey

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5 February 2020

Albert L Hyman

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5 February 2020

publication date

11 June 2010

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5 February 2020

American Journal of Physiology Heart and Circulatory Physiology

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5 February 2020

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5 February 2020

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5 February 2020

H819-26

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5 February 2020

Vascular responses to nitrite are mediated by xanthine oxidoreductase and mitochondrial aldehyde dehydrogenase in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Pulmonary vasodilator responses to sodium nitrite are mediated by an allopurinol-sensitive mechanism in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Bioactivation of nitroglycerin by the mitochondrial aldehyde dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

THE ROLE OF THE VENOUS SYSTEM IN CIRCULATORY COLLAPSE INDUCED BY SODIUM NITRITE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

THE NATURE OF CIRCULATORY COLLAPSE INDUCED BY SODIUM NITRITE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Contribution of aldehyde dehydrogenase to mitochondrial bioactivation of nitroglycerin: evidence for the activation of purified soluble guanylate cyclase through direct formation of nitric oxide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Biochemical mechanism of nitroglycerin action and tolerance: is this old mystery solved?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Does Nitric Oxide Mediate the Vasodilator Activity of Nitroglycerin?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

After 130 years, the molecular mechanism of action of nitroglycerin is revealed

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Identification of the enzymatic mechanism of nitroglycerin bioactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Plasma nitrite rather than nitrate reflects regional endothelial nitric oxide synthase activity but lacks intrinsic vasodilator action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Pulmonary vasodilator responses to nitroprusside and nitroglycerin in the dog.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Biotransformation of organic nitrates to nitric oxide by vascular smooth muscle and endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Hemodynamic effects of nitroglycerin in acute myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Relief of pulmonary congestion by sublingual nitroglycerin in patients with mitral valve disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Synthesis of adenosine 3′,5′-monophosphate by guanylate cyclase, a new pathway for its formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Guanylate cyclase: activation by azide, nitro compounds, nitric oxide, and hydroxyl radical and inhibition by hemoglobin and myoglobin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

5 July 2018

In vitro activation of soluble guanylyl cyclase and nitric oxide release: a comparison of NO donors and NO mimetics

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00959.2009

21 January 2018

Nitrite infusion in humans and nonhuman primates: endocrine effects, pharmacokinetics, and tolerance formation

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00959.2009

21 January 2018

The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00959.2009

21 January 2018

Requirement of thiols for activation of coronary arterial guanylate cyclase by glyceryl trinitrate and sodium nitrite possible involvement of S-nitrosothiols

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00959.2009

21 January 2018

Mitochondrial nitrite reduction coupled to soluble guanylate cyclase activation: lack of evidence for a role in the bioactivation of nitroglycerin.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00959.2009

21 January 2018

Xanthine oxidase catalyzes anaerobic transformation of organic nitrates to nitric oxide and nitrosothiols: characterization of this mechanism and the link between organic nitrate and guanylyl cyclase activation

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00959.2009

21 January 2018

Discrepancies between nitroglycerin and NO-releasing drugs on mitochondrial oxygen consumption, vasoactivity, and the release of NO.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00959.2009

21 January 2018

Role of mitochondrial aldehyde dehydrogenase in nitroglycerin-induced vasodilation of coronary and systemic vessels: an intact canine model

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00959.2009

21 January 2018

The Bradshaw Lecture on some New Vaso-Dilators: Delivered before the Royal College of Physicians of London

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

28 October 2018

Relationship between cyclic guanosine 3':5'-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944483

28 October 2018

Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20543077

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiol agents separate nitric oxide formation from vasodilation induced by glyceryl trinitrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20543077

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the subcellular site for nitroglycerin metabolism to nitric oxide in bovine coronary smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20543077

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactions of strips of rabbit aorta to epinephrine, isopropylarterenol, sodium nitrite and other drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/20543077

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sublingual nitroglycerin in the treatment of left ventricular failure and pulmonary edema

1 reference

https://pubmed.ncbi.nlm.nih.gov/20543077

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/20543077

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardioprotective effects of acidified sodium nitrite in myocardial ischemia with reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20543077

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitrite-dependent vasodilation is facilitated by hypoxia and is independent of known NO-generating nitrite reductase activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/20543077

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glyceryl trinitrate-induced vasodilation is inhibited by ultraviolet irradiation despite enhanced nitric oxide generation: evidence for formation of a nitric oxide conjugate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20543077

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPHEART.00959.2009

1 reference

Europe PubMed Central

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5 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

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5 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20543077%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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