Retinoblastoma tumor suppressor and genome stability (Q34153888)

31 July 2017

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title

Retinoblastoma tumor suppressor and genome stability (English)

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31 July 2017

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1 reference

Lei Zheng

1

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31 July 2017

Wen-Hwa Lee

series ordinal

2

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31 July 2017

publication date

1 January 2002

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Advances in Cancer Research

31 July 2017

published in

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31 July 2017

volume

85

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31 July 2017

page(s)

13-50

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Chromosome assembly in vitro: Topoisomerase II is required for condensation

31 July 2017

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DNA replication control through interaction of E2F-RB and the origin recognition complex

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Retinoblastoma protein recruits histone deacetylase to repress transcription

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General transcription factors bind promoters repressed by Polycomb group proteins.

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Genetic origin of mutations predisposing to retinoblastoma

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Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants

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Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs

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Genetic mechanisms of tumor suppression by the human p53 gene

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Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

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HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis

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HEC Binds to the Seventh Regulatory Subunit of the 26 S Proteasome and Modulates the Proteolysis of Mitotic Cyclins

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Assembly of functionally active Drosophila origin recognition complex from recombinant proteins

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Linking the Rb and polycomb pathways

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7 January 2021

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

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7 January 2021

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

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7 January 2021

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

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7 January 2021

The regulation of E2F by pRB-family proteins

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7 January 2021

Molecular genetics of Bloom's syndrome

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7 January 2021

Probing the architecture of a simple kinetochore using DNA-protein crosslinking

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7 January 2021

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

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7 January 2021

p53 regulation of G(2) checkpoint is retinoblastoma protein dependent

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7 January 2021

Links between replication, recombination and genome instability in eukaryotes

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7 January 2021

Mutations in the APC tumour suppressor gene cause chromosomal instability

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7 January 2021

Reconstitution of a functional core polycomb repressive complex.

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7 January 2021

Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregation

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7 January 2021

Abnormal centrosome amplification in the absence of p53.

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7 January 2021

S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase

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7 January 2021

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

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7 January 2021

The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

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7 January 2021

A Novel Mammalian, Mitotic Spindle–associated Kinase Is Related to Yeast and Fly Chromosome Segregation Regulators

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7 January 2021

Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice

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7 January 2021

WT1-mediated growth suppression of Wilms tumor cells expressing a WT1 splicing variant.

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7 January 2021

The many interfaces of Mre11

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7 January 2021

The Hallmarks of Cancer

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7 January 2021

Chromatin remodeling and Rb activity

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7 January 2021

Cell cycle control and cancer

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7 January 2021

A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

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7 January 2021

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

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7 January 2021

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

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7 January 2021

Chromosome cohesion, condensation, and separation

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7 January 2021

Cell cycle control of higher-order chromatin assembly around naked DNA in vitro

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7 January 2021

The Glc7 type 1 protein phosphatase of Saccharomyces cerevisiae is required for cell cycle progression in G2/M.

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7 January 2021

Genome maintenance mechanisms for preventing cancer

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7 January 2021

DNA topoisomerase II is required at the time of mitosis in yeast

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7 January 2021

DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage.

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7 January 2021

Dissecting the regulatory circuitry of a eukaryotic genome

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7 January 2021

Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes

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7 January 2021

Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

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7 January 2021

Ctf19p: A novel kinetochore protein in Saccharomyces cerevisiae and a potential link between the kinetochore and mitotic spindle

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7 January 2021

Inhibition of DNA topoisomerase II by ICRF-193 induces polyploidization by uncoupling chromosome dynamics from other cell cycle events

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7 January 2021

Effects of an Rb mutation in the mouse

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7 January 2021

The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control

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7 January 2021

The emerging genetic and molecular basis of Fanconi anaemia

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7 January 2021

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

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7 January 2021

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

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7 January 2021

Overproduction of Rb protein after the G1/S boundary causes G2 arrest

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7 January 2021

Loss of heterozygosity on chromosome 17 and mutation of the p53 gene in retinoblastoma

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7 January 2021

Nuclear organization of DNA replication in primary mammalian cells.

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ATP-dependent remodeling and acetylation as regulators of chromatin fluidity

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7 January 2021

Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle

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7 January 2021

Lessons from hereditary colorectal cancer

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7 January 2021

The approaching era of the tumor suppressor genes

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7 January 2021

The domain structure of centromeres is conserved from fission yeast to humans

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7 January 2021

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RB-dependent S-phase response to DNA damage

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Mitotic chromosome condensation.

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Sister chromatid cohesion: the beginning of a long and beautiful relationship

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Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

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7 January 2021

Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

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7 January 2021

RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins

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7 January 2021

The genetic defect in ataxia-telangiectasia

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A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere

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7 January 2021

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

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7 January 2021

Genetic instabilities in human cancers

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Genetic instability in colorectal cancers

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CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis

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7 January 2021

The retinoblastoma gene family in differentiation and development.

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7 January 2021

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

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7 January 2021

Multicolour spectral karyotyping of mouse chromosomes

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7 January 2021

The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T.

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7 January 2021

Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex

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7 January 2021

Rb interacts with histone deacetylase to repress transcription

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7 January 2021

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

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7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

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7 January 2021

Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis

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7 January 2021

A functional assay for centromere-associated sister chromatid cohesion

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7 January 2021

Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae

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7 January 2021

Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

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7 January 2021

Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly

1 reference

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7 January 2021

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

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7 January 2021

Separating sister chromatids

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7 January 2021

Splitting the chromosome: cutting the ties that bind sister chromatids

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7 January 2021

Characterization of the mitotic phase pRb-directed protein phosphatase activity

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7 January 2021

DNA methylation and chromatin modification.

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7 January 2021

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

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7 January 2021

Rb targets histone H3 methylation and HP1 to promoters

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Early loss of the retinoblastoma gene is associated with impaired growth inhibitory innervation during melanotroph carcinogenesis in Rb+/- mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

A putative protein complex consisting of Ctf19, Mcm21, and Okp1 represents a missing link in the budding yeast kinetochore

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Nuf2, a spindle pole body-associated protein required for nuclear division in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

The anaphase-promoting complex: new subunits and regulators

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7 January 2021

The large subunit of replication factor C promotes cell survival after DNA damage in an LxCxE motif- and Rb-dependent manner

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7 January 2021

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

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7 January 2021

Promoter targeting and chromatin remodeling by the SWI/SNF complex

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7 January 2021

The Mre11 complex and ATM: collaborating to navigate S phase

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7 January 2021

A retinoblastoma-binding protein related to a negative regulator of Ras in yeast

1 reference

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7 January 2021

CpG methylation, chromatin structure and gene silencing-a three-way connection

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https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

The retinoblastoma protein: more than a tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Mutations of N-terminal regions render the retinoblastoma protein insufficient for functions in development and tumor suppression.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Segregation of recombined chromosomes in meiosis I requires DNA topoisomerase II.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP.

1 reference

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7 January 2021

The SMC proteins and the coming of age of the chromosome scaffold hypothesis.

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7 January 2021

Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p

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7 January 2021

A Drosophila Polycomb group complex includes Zeste and dTAFII proteins.

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7 January 2021

Novobiocin inhibits passive chromatin assembly in vitro.

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7 January 2021

Studies on DNA topoisomerase activity during in vitro chromatin assembly

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7 January 2021

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

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7 January 2021

Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

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7 January 2021

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

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7 January 2021

Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

SMC proteins and chromosome structure.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Binding of select forms of pRB to protein phosphatase type 1 independent of catalytic activity

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https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Identification of Cohesin Association Sites at Centromeres and along Chromosome Arms

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Targeting of N-CoR and histone deacetylase 3 by the oncoprotein v-erbA yields a chromatin infrastructure-dependent transcriptional repression pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Untangling the role of DNA topoisomerase II in mitotic chromosome structure and function.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Phosphorylation of histone H3 is required for proper chromosome condensation and segregation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Histone deacetylase: a regulator of transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Mitotic chromatin condensation in vitro using somatic cell extracts and nuclei with variable levels of endogenous topoisomerase II.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Cell cycle mechanisms of sister chromatid separation; roles of Cut1/separin and Cut2/securin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Hypophosphorylation of the RB protein in S and G2 as well as G1 during growth arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

The Saccharomyces SHP1 gene, which encodes a regulator of phosphoprotein phosphatase 1 with differential effects on glycogen metabolism, meiotic differentiation, and mitotic cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Hec1p, an evolutionarily conserved coiled-coil protein, modulates chromosome segregation through interaction with SMC proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Retinoblastoma protein enhances the fidelity of chromosome segregation mediated by hsHec1p

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

The retinoblastoma gene: a prototypic and multifunctional tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Lessons learned from BRCA1 and BRCA2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985002-3

7 January 2021

10.1016/S0065-230X(02)85002-3

Identifiers

DOI

1 reference

31 July 2017

1 reference