MRNA stability and the control of gene expression: implications for human disease (Q34162276)

31 July 2017

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title

MRNA stability and the control of gene expression: implications for human disease (English)

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31 July 2017

Elysia M Hollams

1

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31 July 2017

Keith M Giles

series ordinal

2

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31 July 2017

Andrew M Thomson

series ordinal

3

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31 July 2017

Peter J Leedman

series ordinal

4

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31 July 2017

publication date

1 October 2002

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31 July 2017

published in

Neurochemical Research

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31 July 2017

volume

27

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31 July 2017

issue

10

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31 July 2017

page(s)

957-980

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AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: the functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A).

31 July 2017

cites work

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12 December 2020

Embryonic lethal abnormal vision-like RNA-binding proteins regulate neurite outgrowth and tau expression in PC12 cells

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12 December 2020

Recognition of polyadenylate RNA by the poly(A)-binding protein

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12 December 2020

A mechanism for translationally coupled mRNA turnover: interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complex

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12 December 2020

The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism

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12 December 2020

Assaying the polyadenylation state of mRNAs

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12 December 2020

p21(waf1) mRNA contains a conserved element in its 3'-untranslated region that is bound by the Elav-like mRNA-stabilizing proteins.

1 reference

12 December 2020

Assays for analyzing exonucleases in vitro

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12 December 2020

Characterization of c-myc 3' to 5' mRNA decay activities in an in vitro system

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12 December 2020

The exosome of Trypanosoma brucei

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12 December 2020

Regulation of mRNA stability in mammalian cells

1 reference

12 December 2020

Cloning and expression of the thyrotropin-releasing hormone receptor from GH3 rat anterior pituitary cells

1 reference

12 December 2020

Parallel and independent regulation of interleukin-3 mRNA turnover by phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase

1 reference

12 December 2020

Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant

1 reference

12 December 2020

Thermodynamics and kinetics of Hsp70 association with A + U-rich mRNA-destabilizing sequences

1 reference

12 December 2020

Post-transcriptional regulation of gro alpha, beta, gamma, and IL-8 mRNAs by IL-1 beta

1 reference

12 December 2020

Localization and physical mapping of genes encoding the A+U-rich element RNA-binding protein AUF1 to human chromosomes 4 and X

1 reference

12 December 2020

Identification of AUF1 as a parathyroid hormone mRNA 3'-untranslated region-binding protein that determines parathyroid hormone mRNA stability

1 reference

12 December 2020

Adhesion-dependent regulation of an A+U-rich element-binding activity associated with AUF1.

1 reference

12 December 2020

Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation

1 reference

12 December 2020

The transferrin receptor: role in health and disease

1 reference

12 December 2020

Rrp6p, the yeast homologue of the human PM-Scl 100-kDa autoantigen, is essential for efficient 5.8 S rRNA 3' end formation

1 reference

12 December 2020

Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3' end formation of 5.8S rRNA in Saccharomyces cerevisiae

1 reference

12 December 2020

Four highly stable eukaryotic mRNAs assemble 3' untranslated region RNA-protein complexes sharing cis and trans components.

1 reference

12 December 2020

Identification of TIAR as a protein binding to the translational regulatory AU-rich element of tumor necrosis factor alpha mRNA.

1 reference

12 December 2020

The pre-mRNA binding K protein contains a novel evolutionarily conserved motif

1 reference

12 December 2020

Arabidopsis thaliana exosome subunit AtRrp4p is a hydrolytic 3'-->5' exonuclease containing S1 and KH RNA-binding domains

1 reference

12 December 2020

Structure of the C-terminal RNA-binding domain of hnRNP D0 (AUF1), its interactions with RNA and DNA, and change in backbone dynamics upon complex formation with DNA

1 reference

12 December 2020

Poly(A) tail-dependent exonuclease AtRrp41p from Arabidopsis thaliana rescues 5.8 S rRNA processing and mRNA decay defects of the yeast ski6 mutant and is found in an exosome-sized complex in plant and yeast cells

1 reference

12 December 2020

Somatic mRNA turnover mutants implicate tristetraprolin in the interleukin-3 mRNA degradation pathway.

1 reference

12 December 2020

Transferrin and iron in normal, Alzheimer's disease, and Parkinson's disease brain regions

1 reference

12 December 2020

Iron-dependent regulation of ferritin and transferrin receptor expression by the iron-responsive element binding protein

1 reference

12 December 2020

Importance of 5'-terminal blocking structure to stabilize mRNA in eukaryotic protein synthesis

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12 December 2020

Combinatorial mRNA regulation: iron regulatory proteins and iso-iron-responsive elements (Iso-IREs).

1 reference

12 December 2020

The role of the neural growth associated protein B-50/GAP-43 in morphogenesis

1 reference

12 December 2020

Characterization of proteins binding the 3' regulatory region of the IL-3 gene in IL-3-dependent and autocrine-transformed hematopoietic cells.

1 reference

12 December 2020

Gene elav of Drosophila melanogaster: a prototype for neuronal-specific RNA binding protein gene family that is conserved in flies and humans.

1 reference

12 December 2020

Nonsense-mediated mRNA decay in Saccharomyces cerevisiae

1 reference

12 December 2020

G3BP is overexpressed in human tumors and promotes S phase entry

1 reference

12 December 2020

Half-lives of beta and gamma globin messenger RNAs and of protein synthetic capacity in cultured human reticulocytes.

1 reference

12 December 2020

Regulation of EGF-receptor expression by EGF and TGF alpha in epidermoid cancer cells is cell type-specific

1 reference

12 December 2020

The role of elav-like genes, a conserved family encoding RNA-binding proteins, in growth and development

1 reference

12 December 2020

Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay

1 reference

12 December 2020

Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel-Lindau protein

1 reference

12 December 2020

Conserved structures and diversity of functions of RNA-binding proteins

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12 December 2020

mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3' end.

1 reference

12 December 2020

Two different RNA binding activities for the AU-rich element and the poly(A) sequence of the mouse neuronal protein mHuC.

1 reference

12 December 2020

HuR and mRNA stability

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12 December 2020

mRNA poly(A) tail, a 3' enhancer of translational initiation

1 reference

12 December 2020

The Elav-like proteins bind to AU-rich elements and to the poly(A) tail of mRNA

1 reference

12 December 2020

Cellular iron metabolism.

1 reference

12 December 2020

Mutations affecting stability and deadenylation of the yeast MFA2 transcript

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12 December 2020

Expression of the neural RNA-binding protein Musashi1 in human gliomas

1 reference

12 December 2020

GM-CSF and oncogene mRNA stabilities are independently regulated in trans in a mouse monocytic tumor

1 reference

12 December 2020

A hierarchy of Hu RNA binding proteins in developing and adult neurons.

1 reference

12 December 2020

Iron-regulatory protein-1 (IRP-1) is highly conserved in two invertebrate species--characterization of IRP-1 homologues in Drosophila melanogaster and Caenorhabditis elegans

1 reference

12 December 2020

Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene

1 reference

12 December 2020

Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins.

1 reference

12 December 2020

Cloning and functional characterisation of the human TRH receptor

1 reference

12 December 2020

Phosphorylation of tristetraprolin, a potential zinc finger transcription factor, by mitogen stimulation in intact cells and by mitogen-activated protein kinase in vitro

1 reference

12 December 2020

Differential regulation of IRP1 and IRP2 by nitric oxide in rat hepatoma cells

1 reference

12 December 2020

Connecting transcription to messenger RNA processing

1 reference

12 December 2020

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators

1 reference

12 December 2020

Protein ligands to HuR modulate its interaction with target mRNAs in vivo

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12 December 2020

A model of the iron responsive element RNA hairpin loop structure determined from NMR and thermodynamic data

1 reference

12 December 2020

A 3' truncation of MYC caused by chromosomal translocation in a human T-cell leukemia increases mRNA stability.

1 reference

12 December 2020

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

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12 December 2020

Alternative RNA splicing in the nervous system

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12 December 2020

Glyceraldehyde-3-phosphate dehydrogenase selectively binds AU-rich RNA in the NAD(+)-binding region (Rossmann fold).

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12 December 2020

Translational repression by a novel partner of human poly(A) binding protein, Paip2

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12 December 2020

Mechanism of regulation of thyrotropin-releasing hormone receptor messenger ribonucleic acid in stably transfected rat pituitary cells

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12 December 2020

An AU-rich sequence in the 3'-UTR of plasminogen activator inhibitor type 2 (PAI-2) mRNA promotes PAI-2 mRNA decay and provides a binding site for nuclear HuR.

1 reference

12 December 2020

Sequential expression and role of Hu RNA-binding proteins during neurogenesis

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12 December 2020

Regulation of the mRNA-binding protein AUF1 by activation of the beta-adrenergic receptor signal transduction pathway

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12 December 2020

Overexpression of an mRNA-binding protein in human colorectal cancer

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12 December 2020

Translation is required for regulation of histone mRNA degradation

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12 December 2020

Regulating the fate of mRNA: the control of cellular iron metabolism

1 reference

12 December 2020

A novel effect of EGF on mRNA stability

1 reference

12 December 2020

Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation

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12 December 2020

AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

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12 December 2020

Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome

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12 December 2020

Different complexes are formed on the 3′ end of histone mRNA with Nuclear and polyribosomal proteins

1 reference

12 December 2020

Iron regulatory protein 1 is not required for the modulation of ferritin and transferrin receptor expression by iron in a murine pro-B lymphocyte cell line

1 reference

12 December 2020

Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3' UTR and does not involve poly(A) tail shortening.

1 reference

12 December 2020

Poly(A), poly(A) binding protein and the regulation of mRNA stability

1 reference

12 December 2020

Endonucleolytic cleavage of a maternal homeo box mRNA in Xenopus oocytes

1 reference

12 December 2020

AUH, a gene encoding an AU-specific RNA binding protein with intrinsic enoyl-CoA hydratase activity

1 reference

12 December 2020

Characterization of the binding of the RNA-binding protein AUF1 to the human AT(1) receptor mRNA.

1 reference

12 December 2020

The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities

1 reference

12 December 2020

A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

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12 December 2020

A new view of mRNA export: separating the wheat from the chaff

1 reference

12 December 2020

Regulated specific protein binding to a conserved region of the 3'-untranslated region of thyrotropin beta-subunit mRNA.

1 reference

12 December 2020

Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system

1 reference

12 December 2020

Hel-N1/Hel-N2 proteins are bound to poly(A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation

1 reference

12 December 2020

A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA

1 reference

12 December 2020

Rapid responses to oxidative stress mediated by iron regulatory protein.

1 reference

12 December 2020

Complex translocation disrupts c-myc regulation in a human plasma cell myeloma

1 reference

12 December 2020

Translational enhancement of H-ferritin mRNA by interleukin-1 beta acts through 5' leader sequences distinct from the iron responsive element

1 reference

12 December 2020

Selective destabilization of short-lived mRNAs with the granulocyte-macrophage colony-stimulating factor AU-rich 3' noncoding region is mediated by a cotranslational mechanism

1 reference

12 December 2020

Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome

1 reference

12 December 2020

Processing of 9E3 mRNA and regulation of its stability in normal and Rous sarcoma virus-transformed cells

1 reference

12 December 2020

Folding of A+U-rich RNA elements modulates AUF1 binding. Potential roles in regulation of mRNA turnover

1 reference

12 December 2020

Cloning and characterization of a cDNA encoding a novel subtype of rat thyrotropin-releasing hormone receptor

1 reference

12 December 2020

Optimized RNA gel-shift and UV cross-linking assays for characterization of cytoplasmic RNA-protein interactions

1 reference

12 December 2020

A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance

1 reference

12 December 2020

Two isoforms of the thyrotropin-releasing hormone receptor generated by alternative splicing have indistinguishable functional properties

1 reference

12 December 2020

The poly(A) tail inhibits the assembly of a 3'-to-5' exonuclease in an in vitro RNA stability system

1 reference

12 December 2020

The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells

1 reference

12 December 2020

Alterations in the interaction between iron regulatory proteins and their iron responsive element in normal and Alzheimer's diseased brains.

1 reference

12 December 2020

Messenger-RNA-binding proteins and the messages they carry

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12 December 2020

A conserved double-stranded RNA-binding domain

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12 December 2020

Versatile role for hnRNP D isoforms in the differential regulation of cytoplasmic mRNA turnover

1 reference

12 December 2020

Posttranscriptional regulation of thyrotropin beta-subunit messenger ribonucleic acid by thyroid hormone in murine thyrotrope tumor cells: a conserved mechanism across species

1 reference

12 December 2020

AU RNA-binding factors differ in their binding specificities and affinities

1 reference

12 December 2020

Heterogeneous nuclear ribonucleoprotein D0 contains transactivator and DNA-binding domains

1 reference

12 December 2020

Tumor antigen HuR binds specifically to one of five protein-binding segments in the 3'-untranslated region of the neurofibromin messenger RNA.

1 reference

12 December 2020

Ferritin and ceruloplasmin in oxidative damage: review and recent findings.

1 reference

12 December 2020

The pathophysiology of tumor necrosis factors

1 reference

12 December 2020

An inducible cytoplasmic factor (AU-B) binds selectively to AUUUA multimers in the 3' untranslated region of lymphokine mRNA

1 reference

12 December 2020

The yin and yang of the exosome

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12 December 2020

Phosphorylation and activation of both iron regulatory proteins 1 and 2 in HL-60 cells

1 reference

12 December 2020

Human erythroid 5-aminolevulinate synthase: promoter analysis and identification of an iron-responsive element in the mRNA

1 reference

12 December 2020

The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements

1 reference

12 December 2020

Structure and dynamics of the iron responsive element RNA: implications for binding of the RNA by iron regulatory binding proteins

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12 December 2020

RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

1 reference

12 December 2020

Regulation by thyrotropin-releasing hormone (TRH) of TRH receptor mRNA degradation in rat pituitary GH3 cells

1 reference

12 December 2020

A hippocampal protein associated with paraneoplastic neurologic syndrome and small cell lung carcinoma

1 reference

12 December 2020

Dual function of the messenger RNA cap structure in poly(A)-tail-promoted translation in yeast

1 reference

12 December 2020

Novel binding of HuR and poly(C)-binding protein to a conserved UC-rich motif within the 3'-untranslated region of the androgen receptor messenger RNA.

1 reference

12 December 2020

Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G

1 reference

12 December 2020

Paraneoplastic Encephalomyelitis Antigens Bind to the AU-rich Elements of mRNA

1 reference

12 December 2020

Destabilization of human alpha-globin mRNA by translation anti-termination is controlled during erythroid differentiation and is paralleled by phased shortening of the poly(A) tail.

1 reference

12 December 2020

Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase

1 reference

12 December 2020

Killing the messenger: new insights into nonsense-mediated mRNA decay

1 reference

12 December 2020

Assembly of the alpha-globin mRNA stability complex reflects binary interaction between the pyrimidine-rich 3' untranslated region determinant and poly(C) binding protein alphaCP

1 reference

12 December 2020

Cap-dependent deadenylation of mRNA

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12 December 2020

IRP-1 Binding to Ferritin mRNA Prevents the Recruitment of the Small Ribosomal Subunit by the Cap-Binding Complex eIF4F

1 reference

12 December 2020

Mitogens stimulate the rapid nuclear to cytosolic translocation of tristetraprolin, a potential zinc-finger transcription factor

1 reference

12 December 2020

Degradation of ribosomal RNA precursors by the exosome

1 reference

12 December 2020

A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation

1 reference

12 December 2020

Ubiquitin-dependent mechanism regulates rapid turnover of AU-rich cytokine mRNAs

1 reference

12 December 2020

Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs

1 reference

12 December 2020

Rapid mRNA degradation mediated by the c-fos 3' AU-rich element and that mediated by the granulocyte-macrophage colony-stimulating factor 3' AU-rich element occur through similar polysome-associated mechanisms

1 reference

12 December 2020

The Elav-like proteins bind to a conserved regulatory element in the 3'-untranslated region of GAP-43 mRNA.

1 reference

12 December 2020

A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation

1 reference

12 December 2020

Circularization of mRNA by eukaryotic translation initiation factors

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12 December 2020

Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis

1 reference

12 December 2020

Purification and properties of HuD, a neuronal RNA-binding protein.

1 reference

12 December 2020

Isolation and characterization of a novel, low abundance hnRNP protein: A0

1 reference

12 December 2020

Loops and bulge/loops in iron-responsive element isoforms influence iron regulatory protein binding. Fine-tuning of mRNA regulation?

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12 December 2020

Regulation of c-myc mRNA stability in vitro by a labile destabilizer with an essential nucleic acid component

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12 December 2020

Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2

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12 December 2020

The identification of an endonuclease that cleaves within an HuR binding site in mRNA.

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12 December 2020

Cytokine messenger RNA stability is enhanced in tumor cells

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12 December 2020

Chromosomal localization of nucleic acid-binding proteins by affinity mapping: assignment of the IRE-binding protein gene to human chromosome 9

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12 December 2020

The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation

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12 December 2020

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

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12 December 2020

Monitoring mRNA decapping activity.

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12 December 2020

Cytoplasmic localization is required for the mammalian ELAV-like protein HuD to induce neuronal differentiation

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12 December 2020

The molecular mechanisms of messenger RNA nuclear export

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12 December 2020

Extreme instability of myc mRNA in normal and transformed human cells.

1 reference

12 December 2020

Detection of the anti-Hu antibody in specific regions of the nervous system and tumor from patients with paraneoplastic encephalomyelitis/sensory neuronopathy

1 reference

12 December 2020

HuR regulates p21 mRNA stabilization by UV light

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12 December 2020

Identification of an AUUUA-specific messenger RNA binding protein

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12 December 2020

Antiserum from a patient with cerebellar degeneration identifies a novel protein in Purkinje cells, cortical neurons, and neuroectodermal tumors

1 reference

12 December 2020

Degradation of apolipoprotein II mRNA occurs via endonucleolytic cleavage at 5'-AAU-3'/5'-UAA-3' elements in single-stranded loop domains of the 3'-noncoding region

1 reference

12 December 2020

Polymorphism in the 3'-untranslated region of TNFalpha mRNA impairs binding of the post-transcriptional regulatory protein HuR to TNFalpha mRNA.

1 reference

12 December 2020

Autoregulatory control of beta-tubulin mRNA stability is linked to translation elongation

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12 December 2020

Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover

1 reference

12 December 2020

The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR.

1 reference

12 December 2020

ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells

1 reference

12 December 2020

Purification and characterization of beta-adrenergic receptor mRNA-binding proteins

1 reference

12 December 2020

Repeating structure of cytoplasmic poly(A)-ribonucleoprotein

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12 December 2020

Purification of an AU-rich RNA binding protein from Sarcophaga peregrina (flesh fly) and its identification as a Thiolase.

1 reference

12 December 2020

Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein

1 reference

12 December 2020

Analysis of the RNA recognition motifs of human neuronal ELAV-like proteins in binding to a cytokine mRNA.

1 reference

12 December 2020

Translational inhibition in vitro of human papillomavirus type 16 L2 mRNA mediated through interaction with heterogenous ribonucleoprotein K and poly(rC)-binding proteins 1 and 2.

1 reference

12 December 2020

Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins

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12 December 2020

Iron-regulatory proteins, iron-responsive elements and ferritin mRNA translation

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12 December 2020

Posttranscriptional up-regulation of thyrotropin-releasing hormone (TRH) receptor messenger ribonucleic acid by TRH in COS-1 cells transfected with mouse pituitary TRH receptor complementary deoxyribonucleic acid

1 reference

12 December 2020

Selective degradation of early-response-gene mRNAs: functional analyses of sequence features of the AU-rich elements

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12 December 2020

Characterization of a second RNA-binding protein in rodents with specificity for iron-responsive elements

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12 December 2020

The expression of the Hu (paraneoplastic encephalomyelitis/sensory neuronopathy) antigen in human normal and tumor tissues

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12 December 2020

Removal of an mRNA destabilizing element correlates with the increased oncogenicity of proto-oncogene fos.

1 reference

12 December 2020

The ends of the affair: capping and polyadenylation.

1 reference

12 December 2020

Differential effects of aromatic and charged residue substitutions in the RNA binding domains of the yeast poly(A)-binding protein

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12 December 2020

HuA and tristetraprolin are induced following T cell activation and display distinct but overlapping RNA binding specificities

1 reference

12 December 2020

Neuron-specific hel-N1 and HuD as novel molecular markers of neuroblastoma: a correlation of HuD messenger RNA levels with favorable prognostic features

1 reference

12 December 2020

A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA.

1 reference

12 December 2020

The iron-sulfur cluster of iron regulatory protein 1 modulates the accessibility of RNA binding and phosphorylation sites

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12 December 2020

DNA vaccination with HuD inhibits growth of a neuroblastoma in mice.

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12 December 2020

Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR

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12 December 2020

Molecular basis for the recently described hereditary hyperferritinemia-cataract syndrome: a mutation in the iron-responsive element of ferritin L-subunit gene (the "Verona mutation")

1 reference

12 December 2020

Structure and interactions with RNA of the N-terminal UUAG-specific RNA-binding domain of hnRNP D0

1 reference

12 December 2020

HuR binds a cyclic nucleotide-dependent, stabilizing domain in the 3' untranslated region of Na(+)/glucose cotransporter (SGLT1) mRNA.

1 reference

12 December 2020

Structural determinants in AUF1 required for high affinity binding to A + U-rich elements

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12 December 2020

A novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elements

1 reference

12 December 2020

HNS, a nuclear-cytoplasmic shuttling sequence in HuR

1 reference

12 December 2020

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

1 reference

12 December 2020

HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal

1 reference

12 December 2020

Hu antigens: Reactivity with hu antibodies, tumor expression, and major immunogenic sites

1 reference

12 December 2020

An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro

1 reference

12 December 2020

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

1 reference

12 December 2020

Cyclic nucleotide regulation of type-1 plasminogen activator-inhibitor mRNA stability in rat hepatoma cells. Identification of cis-acting sequences

1 reference

12 December 2020

Rearrangement of CCND1 (BCL1/PRAD1) 3' untranslated region in mantle-cell lymphomas and t(11q13)-associated leukemias.

1 reference

12 December 2020

Sequence-specific endonucleolytic cleavage and protection of mRNA in Xenopus and Drosophila

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12 December 2020

Transcriptional pulsing approaches for analysis of mRNA turnover in mammalian cells

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12 December 2020

Translational regulation of mRNAs with distinct IRE sequences by iron regulatory proteins 1 and 2

1 reference

12 December 2020

Complex contribution of the 3'-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR.

1 reference

12 December 2020

Detection and characterization of a 3' untranslated region ribonucleoprotein complex associated with human alpha-globin mRNA stability

1 reference

12 December 2020

Identification and characterization of proteins binding A + U-rich elements

1 reference

12 December 2020

Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1

1 reference

12 December 2020

3'-End processing of pre-mRNA in eukaryotes

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12 December 2020

Why is Hu where? Shuttling of early-response-gene messenger RNA subsets

1 reference

12 December 2020

Rapid cytoplasmic turnover of c-myc mRNA: requirement of the 3' untranslated sequences

1 reference

12 December 2020

The mRNA poly(A)-binding protein: localization, abundance, and RNA-binding specificity.

1 reference

12 December 2020

Gene suppression by tristetraprolin and release by the p38 pathway

1 reference

12 December 2020

mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation

1 reference

12 December 2020

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

1 reference

12 December 2020

AUF1 binding affinity to A+U-rich elements correlates with rapid mRNA degradation

1 reference

12 December 2020

Poly(A) tail shortening by a mammalian poly(A)-specific 3'-exoribonuclease

1 reference

12 December 2020

Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.

1 reference

12 December 2020

Expression cloning of a cDNA encoding the mouse pituitary thyrotropin-releasing hormone receptor

1 reference

12 December 2020

Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay

1 reference

12 December 2020

Iron metabolism in inflammation

1 reference

12 December 2020

Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes

1 reference

12 December 2020

Site-specific cleavage of IGF-II mRNAs requires sequence elements from two distinct regions of the IGF-II gene

1 reference

12 December 2020

The exosome: a proteasome for RNA?

1 reference

12 December 2020

Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation

1 reference

12 December 2020

Poly(A) tail shortening is the translation-dependent step in c-myc mRNA degradation

1 reference

12 December 2020

Endonucleolysis in the turnover of insulin-like growth factor II mRNA.

1 reference

12 December 2020

A protein of molecular weight 78,000 bound to the polyadenylate region of eukaryotic messenger RNAs

1 reference

12 December 2020

Three-dimensional structure and stability of the KH domain: molecular insights into the fragile X syndrome

1 reference

12 December 2020

Abnormal localization of iron regulatory protein in Alzheimer's disease.

1 reference

12 December 2020

The mRNA cap structure stimulates rate of poly(A) removal and amplifies processivity of degradation

1 reference

12 December 2020

1 reference

12 December 2020

The exosome subunit Rrp43p is required for the efficient maturation of 5.8S, 18S and 25S rRNA.

1 reference

12 December 2020

Interactions of CCCH zinc finger proteins with mRNA: tristetraprolin-mediated AU-rich element-dependent mRNA degradation can occur in the absence of a poly(A) tail

1 reference

12 December 2020

Structure and genomic organization of the human AUF1 gene: alternative pre-mRNA splicing generates four protein isoforms

1 reference

12 December 2020

Determinants that contribute to cytoplasmic stability of human c-fos and beta-globin mRNAs are located at several sites in each mRNA.

1 reference

12 December 2020

The Nuclease That Selectively Degrades Albumin mRNA in Vitro Associates with Xenopus Liver Polysomes through the 80S Ribosome Complex

1 reference

12 December 2020

AU-rich elements: characterization and importance in mRNA degradation

1 reference

12 December 2020

Hel-N1, an RNA-binding protein, is a ligand for an A + U rich region of the GLUT1 3' UTR.

1 reference

12 December 2020

The stem-loop structure at the 3' end of histone mRNA is necessary and sufficient for regulation of histone mRNA stability

1 reference

12 December 2020

Removal of a 3' non-coding sequence is an initial step in degradation of gro alpha mRNA and is regulated by interleukin-1

1 reference

12 December 2020

Regulation of c-myc mRNA decay in vitro by a phorbol ester-inducible, ribosome-associated component in differentiating megakaryoblasts

1 reference

12 December 2020

Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice

1 reference

12 December 2020

Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif

1 reference

12 December 2020

Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript

1 reference

12 December 2020

HuR binding to cytoplasmic mRNA is perturbed by heat shock

1 reference

12 December 2020

Xenopus poly(A) binding protein: functional domains in RNA binding and protein-protein interaction

1 reference

12 December 2020

A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation

1 reference

12 December 2020

Functions of the exosome in rRNA, snoRNA and snRNA synthesis

1 reference

12 December 2020

Characterization and purification of a mammalian endoribonuclease specific for the alpha -globin mRNA.

1 reference

12 December 2020

Identification of bovine glutamate dehydrogenase as an RNA-binding protein

1 reference

12 December 2020

Expression of thyrotropin-releasing hormone receptor 2 (TRH-R2) in the central nervous system of rats

1 reference

12 December 2020

Identification of a novel AU-Rich element in the 3' untranslated region of epidermal growth factor receptor mRNA that is the target for regulated RNA-binding proteins

1 reference

12 December 2020

Identification of the poly(C) binding protein in the complex associated with the 3' untranslated region of erythropoietin messenger RNA.

1 reference

12 December 2020

The effect of capping and polyadenylation on the stability, movement and translation of synthetic messenger RNAs in Xenopus oocytes.

1 reference

12 December 2020

Choreographing mRNA biogenesis

1 reference

12 December 2020

The iron responsive element (IRE) family of mRNA regulators. Regulation of iron transport and uptake compared in animals, plants, and microorganisms.

1 reference

12 December 2020

Identification of the NAD(+)-binding fold of glyceraldehyde-3-phosphate dehydrogenase as a novel RNA-binding domain.

1 reference

12 December 2020

The locus elav of Drosophila melanogaster is expressed in neurons at all developmental stages.

1 reference

12 December 2020

Removal of a 67-base-pair sequence in the noncoding region of protooncogene fos converts it to a transforming gene

1 reference

12 December 2020

Post-transcriptional regulation of vascular endothelial growth factor by hypoxia

1 reference

12 December 2020

Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs

1 reference

12 December 2020

Thyrotropin-releasing hormone and epidermal growth factor regulate iron-regulatory protein binding in pituitary cells via protein kinase C-dependent and -independent signaling pathways

1 reference

12 December 2020

Iron regulatory proteins 1 and 2 bind distinct sets of RNA target sequences

1 reference

12 December 2020

Assembly of AUF1 oligomers on U-rich RNA targets by sequential dimer association

1 reference

12 December 2020

From transcript to protein

1 reference

12 December 2020

HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation

1 reference

12 December 2020

Targeting an mRNA for decapping: displacement of translation factors and association of the Lsm1p-7p complex on deadenylated yeast mRNAs

1 reference

12 December 2020

The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes.

1 reference

12 December 2020

Translation and a 42-nucleotide segment within the coding region of the mRNA encoded by the MAT alpha 1 gene are involved in promoting rapid mRNA decay in yeast

1 reference

12 December 2020

The human gene for the poly(A)-specific ribonuclease (PARN) maps to 16p13 and has a truncated copy in the Prader-Willi/Angelman syndrome region on 15q11-->q13

1 reference

12 December 2020

Structural and functional features of eukaryotic mRNA untranslated regions

1 reference

12 December 2020

Two functional complexes formed by KH domain containing proteins with the 5' noncoding region of poliovirus RNA.

1 reference

12 December 2020

The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation

1 reference

12 December 2020

A single gene from yeast for both nuclear and cytoplasmic polyadenylate-binding proteins: domain structure and expression

1 reference

12 December 2020

The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs

1 reference

12 December 2020

Translational control during the acute phase response. Ferritin synthesis in response to interleukin-1

1 reference

12 December 2020

The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases

1 reference

12 December 2020

Comparative sequence analysis of ribonucleases HII, III, II PH and D

1 reference

12 December 2020

Amplification in human breast cancer of a gene encoding a c-myc mRNA-binding protein

1 reference

12 December 2020

Mutant alleles at the locus elav in Drosophila melanogaster lead to nervous system defects. A developmental-genetic analysis.

1 reference

12 December 2020

The Role of the Poly(A) Sequence in Mammalian Messenger RN

1 reference

12 December 2020

Iron regulates cytoplasmic levels of a novel iron-responsive element-binding protein without aconitase activity

1 reference

12 December 2020

Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis

1 reference

12 December 2020

In vitro properties of the conserved mammalian protein hnRNP D suggest a role in telomere maintenance

1 reference

12 December 2020

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

1 reference

12 December 2020

Mutational analysis of the [4Fe-4S]-cluster converting iron regulatory factor from its RNA-binding form to cytoplasmic aconitase

1 reference

12 December 2020

The c-myc coding region determinant-binding protein: a member of a family of KH domain RNA-binding proteins

1 reference

12 December 2020

Iron and gene expression: molecular mechanisms regulating cellular iron homeostasis.

1 reference

12 December 2020

Erythroid cell-specific mRNA stability elements in the alpha 2-globin 3' nontranslated region

1 reference

12 December 2020

ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins

1 reference

12 December 2020

Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3' AU-rich sequences

1 reference

12 December 2020

Association of heterogeneous nuclear ribonucleoprotein A1 and C proteins with reiterated AUUUA sequences

1 reference

12 December 2020

A specific isoform of hnRNP D interacts with DNA in the LR1 heterodimer: canonical RNA binding motifs in a sequence-specific duplex DNA binding protein

1 reference

12 December 2020

Specific binding of human dihydrofolate reductase protein to dihydrofolate reductase messenger RNA in vitro

1 reference

12 December 2020

Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems

1 reference

12 December 2020

Identification of AUF1 (heterogeneous nuclear ribonucleoprotein D) as a component of the alpha-globin mRNA stability complex

1 reference

12 December 2020

A stem-loop in the 3' untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm.

1 reference

12 December 2020

Human mRNA polyadenylate binding protein: evolutionary conservation of a nucleic acid binding motif

1 reference

12 December 2020

Hormonal regulation of mRNA stability and RNA-protein interactions in the pituitary

1 reference

12 December 2020

Yeast mitochondrial NAD(+)-dependent isocitrate dehydrogenase is an RNA-binding protein

1 reference

12 December 2020

Identification of two KH domain proteins in the alpha-globin mRNP stability complex

1 reference

12 December 2020

Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs

1 reference

12 December 2020

Starting at the beginning, middle, and end: translation initiation in eukaryotes

1 reference

12 December 2020

Translational regulation of mammalian and Drosophila citric acid cycle enzymes via iron-responsive elements

1 reference

12 December 2020

HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine- and uridine-rich elements within the 3' untranslated regions of cytokine and angiogenic factor mRNAs

1 reference

12 December 2020

Mechanism and regulation of mRNA polyadenylation

1 reference

12 December 2020

Transferrin receptors promote the formation of clathrin lattices

1 reference

12 December 2020

The aconitase family: three structural variations on a common theme

1 reference

12 December 2020

Succinate dehydrogenase b mRNA of Drosophila melanogaster has a functional iron-responsive element in its 5'-untranslated region

1 reference

12 December 2020

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

1 reference

12 December 2020

Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1

1 reference

12 December 2020

Functional link between the mammalian exosome and mRNA decapping

1 reference

12 December 2020

Tissue-specific regulation of iron metabolism and heme synthesis: distinct control mechanisms in erythroid cells.

1 reference

12 December 2020

A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency

1 reference

12 December 2020

Rapid degradation of AU-rich element (ARE) mRNAs is activated by ribosome transit and blocked by secondary structure at any position 5' to the ARE.

1 reference

12 December 2020

Iron is hot: an update on the pathophysiology of hemochromatosis

1 reference

12 December 2020

Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability

1 reference

12 December 2020

Mutation in the iron responsive element of the L ferritin mRNA in a family with dominant hyperferritinaemia and cataract

1 reference

12 December 2020

Expression of HuD protein is essential for initial phase of neuronal differentiation in rat pheochromocytoma PC12 cells

1 reference

12 December 2020

The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency

1 reference

12 December 2020

The poly(A)-poly(A)-binding protein complex is a major determinant of mRNA stability in vitro

1 reference

12 December 2020

Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade

1 reference

12 December 2020

Identification of sequences within the murine granulocyte-macrophage colony-stimulating factor mRNA 3'-untranslated region that mediate mRNA stabilization induced by mitogen treatment of EL-4 thymoma cells

1 reference

12 December 2020

AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation

1 reference

12 December 2020

The human cytochrome P450 1A1 mRNA is rapidly degraded in HepG2 cells

1 reference

12 December 2020

Paraneoplastic syndromes

1 reference

12 December 2020

Interplay of two functionally and structurally distinct domains of the c-fos AU-rich element specifies its mRNA-destabilizing function

1 reference

12 December 2020

1 reference

12 December 2020

Differential posttranscriptional regulation of androgen receptor gene expression by androgen in prostate and breast cancer cells

1 reference

12 December 2020

A cytokine mRNA-destabilizing element that is structurally and functionally distinct from A+U-rich elements.

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1020992418511

1 reference

Dimensions Publication ID

31 July 2017

1020032935

0 references

1 reference