Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations (Q34170551)

31 July 2017

title

Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations (English)

1 reference

31 July 2017

1 reference

1 reference

Nikhil Singla

1

1 reference

31 July 2017

Yehuda Goldgur

2

1 reference

31 July 2017

Kai Xu

3

1 reference

31 July 2017

Sari Paavilainen

4

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31 July 2017

Dimitar B. Nikolov

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20678482

15 June 2024

Juha P. Himanen

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20678482

15 June 2024

language of work or name

English

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publication date

1 August 2010

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31 July 2017

3 September 2010

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20678482

full work available at URL

15 June 2024

https://europepmc.org/articles/pmc2949057?pdf=render

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20678482/?tool=EBI

15 June 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20678482

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20678482/pdf/?tool=EBI

15 June 2024

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https://europepmc.org/articles/PMC2949057

15 June 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20678482

https://europepmc.org/articles/PMC2949057?pdf=render

15 June 2024

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content deliverer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20678482

https://doi.org/10.1016/j.bbrc.2010.07.109

15 June 2024

online access status

open access

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https://api.elsevier.com/content/article/PII:S0006291X10014294?httpAccept=text/xml

15 June 2024

1 reference

10.1016/J.BBRC.2010.07.109

Crossref

DOI

https://api.crossref.org/works/10.1016/J.BBRC.2010.07.109

https://api.elsevier.com/content/article/PII:S0006291X10014294?httpAccept=text/plain

15 June 2024

1 reference

10.1016/J.BBRC.2010.07.109

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DOI

https://api.crossref.org/works/10.1016/J.BBRC.2010.07.109

Biochemical and Biophysical Research Communications

15 June 2024

published in

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31 July 2017

volume

399

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31 July 2017

issue

4

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31 July 2017

page(s)

555-559

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Architecture of Eph receptor clusters

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

Structural Characterization of the EphA4-Ephrin-B2 Complex Reveals New Features Enabling Eph-Ephrin Binding Promiscuity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

Structural Plasticity of Eph Receptor A4 Facilitates Cross-Class Ephrin Signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

Phasercrystallographic software

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

Structure of the ligand-binding domain of the EphB2 receptor at 2 Å resolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

Toward the semisynthesis of multidomain transmembrane receptors: modification of Eph tyrosine kinases

5 July 2018

1 reference

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Eph-ephrin bidirectional signaling in physiology and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

Cell-cell signaling via Eph receptors and ephrins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets.

5 July 2018

1 reference

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Structures of axon guidance molecules and their neuronal receptors

5 July 2018

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Refinement of macromolecular structures by the maximum-likelihood method

5 July 2018

1 reference

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Automated refinement of protein models

5 July 2018

1 reference

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The CCP4 suite: programs for protein crystallography

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

Eph signaling: a structural view

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

Crystal structure of an Eph receptor-ephrin complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

The EphA4 and EphB1 receptor tyrosine kinases and ephrin-B2 ligand regulate targeted migration of branchial neural crest cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949057

10.1016/J.BBRC.2010.07.109

28 October 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference

31 July 2017

1 reference