Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells (Q34171596)

31 July 2017

Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells (English)

1 reference

31 July 2017

1 reference

Toran Sanli

1

1 reference

31 July 2017

Katja Linher-Melville

series ordinal

2

1 reference

31 July 2017

Theodoros Tsakiridis

series ordinal

3

1 reference

31 July 2017

Gurmit Singh

series ordinal

4

1 reference

31 July 2017

language of work or name

English

0 references

publication date

20 February 2012

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31 July 2017

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31 July 2017

7

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31 July 2017

e32035

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31 July 2017

2

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Creative Commons Attribution 4.0 International

31 July 2017

start time

20 February 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Lovastatin sensitizes lung cancer cells to ionizing radiation: modulation of molecular pathways of radioresistance and tumor suppression

5 July 2018

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Stressin' Sestrins take an aging fight

5 July 2018

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Stress-responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signaling

5 July 2018

1 reference

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Ionizing radiation activates AMP-activated kinase (AMPK): a target for radiosensitization of human cancer cells

5 July 2018

1 reference

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FoxOs inhibit mTORC1 and activate Akt by inducing the expression of Sestrin3 and Rictor

5 July 2018

1 reference

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Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies

5 July 2018

1 reference

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Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer.

5 July 2018

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Regulation of protein synthesis by ionizing radiation.

5 July 2018

1 reference

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AMPK in Health and Disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

Stimulation of autophagy by the p53 target gene Sestrin2.

5 July 2018

1 reference

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AMPK: Lessons from transgenic and knockout animals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis

5 July 2018

1 reference

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Ageing, oxidative stress and cancer: paradigms in parallax

5 July 2018

1 reference

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p53 strikes mTORC1 by employing sestrins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

AMPK: a key regulator of energy balance in the single cell and the whole organism.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

TOR signaling in growth and metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

The antioxidant function of the p53 tumor suppressor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD

5 July 2018

1 reference

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The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

PA26 is a candidate gene for heterotaxia in humans: identification of a novel PA26-related gene family in human and mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

AMPK regulates metabolism and survival in response to ionizing radiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

AMP-activated protein kinase subunit interactions: beta1:gamma1 association requires beta1 Thr-263 and Tyr-267.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282792

Localization of AMP kinase is regulated by stress, cell density, and signaling through the MEK-->ERK1/2 pathway

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22363791

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0032035

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference