MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300 (Q34177495)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12588875%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

title

MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300 (English)

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31 October 2019

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2

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31 October 2019

author name string

Nianli Sang

1

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31 October 2019

Jolene Bohensky

3

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31 October 2019

Irene Leshchinsky

4

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31 October 2019

Vickram Srinivas

5

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31 October 2019

Jaime Caro

6

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31 October 2019

language of work or name

English

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publication date

13 February 2003

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Journal of Biological Chemistry

31 October 2019

published in

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31 October 2019

volume

278

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31 October 2019

issue

16

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31 October 2019

page(s)

14013-14019

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Regulation of gene expression by the hypoxia-inducible factors

31 October 2019

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

5 July 2018

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5 July 2018

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5 July 2018

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Stimulation of p300-mediated transcription by the kinase MEKK1.

5 July 2018

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Molecular mechanism of hypoxia-inducible factor 1alpha -p300 interaction. A leucine-rich interface regulated by a single cysteine

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

5 July 2018

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5 July 2018

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An essential role for p300/CBP in the cellular response to hypoxia

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Effect of protein kinase and phosphatase inhibitors on expression of hypoxia-inducible factor 1.

5 July 2018

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p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

5 July 2018

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The transcriptional activation function of the HIF-like factor requires phosphorylation at a conserved threonine

21 January 2018

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MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1alpha in rasV12 upregulation of VEGF.

21 January 2018

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21 January 2018

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CBP/p300 Integrates Raf/Rac-Signaling Pathways in the Transcriptional Induction of NF-ATc during T Cell Activation

21 January 2018

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Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12588875

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Roles of p300, pocket proteins, and hTBP in E1A-mediated transcriptional regulation and inhibition of p53 transactivation activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12588875

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

EPAS1 trans-activation during hypoxia requires p42/p44 MAPK

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12588875

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M209702200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12588875%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12588875%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

PubMed publication ID

12588875

1 reference