PTEN and myotubularin phosphoinositide phosphatases: bringing bioinformatics to the lab bench (Q34180652)

31 July 2017

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title

PTEN and myotubularin phosphoinositide phosphatases: bringing bioinformatics to the lab bench (English)

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31 July 2017

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4

J E Dixon

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31 July 2017

M J Wishart

1

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31 July 2017

G S Taylor

series ordinal

2

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31 July 2017

J T Slama

series ordinal

3

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31 July 2017

publication date

1 April 2001

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Current Opinion in Cell Biology

31 July 2017

published in

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31 July 2017

volume

13

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31 July 2017

issue

2

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31 July 2017

page(s)

172-181

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Signalling through phosphoinositide 3-kinases: the lipids take centre stage

31 July 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Pathways for phosphoinositide synthesis

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7 January 2021

Phosphoinositides in membrane traffic

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7 January 2021

Phosphoinositide signaling and the regulation of membrane trafficking in yeast

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Protein tyrosine phosphatases: mechanisms of catalysis and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

PTEN: a tumour suppressor that functions as a phospholipid phosphatase

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Myotubularin, a phosphatase deficient in myotubular myopathy, acts on phosphatidylinositol 3-kinase and phosphatidylinositol 3-phosphate pathway

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

The multiple roles of PTEN in tumor suppression

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Forkhead transcription factors: new insights into protein kinase B (c-akt) signaling.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Protein kinases: six degrees of separation?

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Serine/threonine protein kinases and apoptosis.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Intracellular signalling: PDK1--a kinase at the hub of things

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

The PI3K-PDK1 connection: more than just a road to PKB

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Cellular signaling: pivoting around PDK-1.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Impaired Fas response and autoimmunity in Pten+/- mice

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Regulation of dauer larva development in Caenorhabditis elegans by daf-18, a homologue of the tumour suppressor PTEN

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Transcriptional activation of p21WAF1 by PTEN/MMAC1 tumor suppressor

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

C2-domains, structure and function of a universal Ca2+-binding domain

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Inhibition of H-Ras transformation by the PTEN/MMAC1/TEP1 tumor suppressor gene

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Phosphorylation of the PTEN tail regulates protein stability and function

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

A testis-specific gene, TPTE, encodes a putative transmembrane tyrosine phosphatase and maps to the pericentromeric region of human chromosomes 21 and 13, and to chromosomes 15, 22, and Y

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

MTM1 mutations in X-linked myotubular myopathy

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Association of SET domain and myotubularin-related proteins modulates growth control

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Sac phosphatase domain proteins.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

A sensitive assay for phosphoinositide phosphatases

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatases.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

FYVE fingers bind PtdIns(3)P

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

A functional PtdIns(3)P-binding motif

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

FYVE-DSP1, a dual-specificity protein phosphatase containing an FYVE domain

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

A single mutation converts a novel phosphotyrosine binding domain into a dual-specificity phosphatase.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

GRAM, a novel domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

SMART: a web-based tool for the study of genetically mobile domains

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900195-2

7 January 2021

10.1016/S0955-0674(00)00195-2

Identifiers

DOI

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31 July 2017

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