Transcriptional activation of p21WAF1 by PTEN/MMAC1 tumor suppressor (Q40892936)

24 September 2017

Transcriptional activation of p21WAF1 by PTEN/MMAC1 tumor suppressor (English)

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24 September 2017

R C Wu

1

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24 September 2017

X Li

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2

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24 September 2017

A H Schönthal

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3

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24 September 2017

1 January 2000

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Molecular and Cellular Biochemistry

24 September 2017

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24 September 2017

203

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24 September 2017

1-2

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24 September 2017

59-71

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https://scigraph.springernature.com/pub.10.1023/a:1007024624967

24 September 2017

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cites work

Overexpression of activin A inhibits growth, induces apoptosis, and suppresses tumorigenicity in an androgen-sensitive human prostate cancer cell line LNCaP.

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12 December 2020

Interaction of adenoviral proteins with pRB and p53.

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12 December 2020

Pten is essential for embryonic development and tumour suppression

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12 December 2020

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

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12 December 2020

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

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12 December 2020

Inhibition of histone H1 kinase expression, retinoblastoma protein phosphorylation, and cell proliferation by the phosphatase inhibitor okadaic acid.

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12 December 2020

Induction of p21 mediated by reactive oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells

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12 December 2020

Cleavage of poly(ADP-ribose) polymerase: a sensitive parameter to study cell death

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12 December 2020

Regulation of p21WAF1/CIP1 expression by p53-independent pathways.

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12 December 2020

Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase

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12 December 2020

The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene

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12 December 2020

Transfection of wild-type but not mutant p53 induces early monocytic differentiation in HL60 cells and increases their sensitivity to stress

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12 December 2020

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

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12 December 2020

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

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12 December 2020

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

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12 December 2020

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

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12 December 2020

Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

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12 December 2020

In vitro loss of heterozygosity targets the PTEN/MMAC1 gene in melanoma

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12 December 2020

WAF1, a potential mediator of p53 tumor suppression

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12 December 2020

Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease.

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12 December 2020

p53 and chemosensitivity

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12 December 2020

p53, the cellular gatekeeper for growth and division

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12 December 2020

Involvement of the Sp3 transcription factor in induction of p21Cip1/WAF1 in keratinocyte differentiation

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12 December 2020

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

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12 December 2020

p21WAF1/CIP1/SDI1 is elevated through a p53-independent pathway by mimosine

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12 December 2020

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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12 December 2020

Signalling through the lipid products of phosphoinositide-3-OH kinase

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12 December 2020

Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

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12 December 2020

Cdk inhibitors in development and cancer

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12 December 2020

Autoregulation of protein phosphatase type 2A expression

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12 December 2020

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

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12 December 2020

Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer.

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12 December 2020

Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

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12 December 2020

Mechanisms of regulation of WAF1/Cip1 gene expression in human breast carcinoma: role of p53-dependent and independent signal transduction pathways

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12 December 2020

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

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12 December 2020

Progesterone regulates transcription of the p21(WAF1) cyclin- dependent kinase inhibitor gene through Sp1 and CBP/p300.

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12 December 2020

PTEN: sometimes taking it off can be better than putting it on.

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12 December 2020

Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway

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12 December 2020

Inhibitors of mammalian G1 cyclin-dependent kinases

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12 December 2020

Role of p53 in aziridinylbenzoquinone-induced p21waf1 expression

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12 December 2020

Redox-Mediated Regulation of p21Waf1/Cip1 Expression Involves a Post-Transcriptional Mechanism and Activation of the Mitogen-Activated Protein Kinase Pathway

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12 December 2020

TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta

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12 December 2020

Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas.

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12 December 2020

Activation of p53-p21waf1 pathway in response to disruption of cell-matrix interactions

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12 December 2020

Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs).

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12 December 2020

Analysis of the p53 gene and its expression in human glioblastoma cells

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12 December 2020

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

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12 December 2020

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

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12 December 2020

Tumor suppressor genes

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12 December 2020

Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents

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12 December 2020

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

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12 December 2020

Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain

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12 December 2020

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

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12 December 2020

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

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12 December 2020

Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues

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12 December 2020

Principles of CDK regulation

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12 December 2020

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

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12 December 2020

p53 and treatment of bladder cancer

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12 December 2020

Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

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12 December 2020

Characteristics of a human cell line transformed by DNA from human adenovirus type 5

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12 December 2020

p53 tumor suppressor gene: from the basic research laboratory to the clinic--an abridged historical perspective

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12 December 2020

Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.

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12 December 2020

p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents.

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1007024624967

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Dimensions Publication ID

24 September 2017

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