Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa (Q34180978)

31 July 2017

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title

Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa (English)

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31 July 2017

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Roberts CW

1

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31 July 2017

McLeod R

2

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31 July 2017

Rice DW

3

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31 July 2017

Ginger M

4

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31 July 2017

Chance ML

5

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31 July 2017

Goad LJ

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31 July 2017

language of work or name

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1 February 2003

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Molecular and Biochemical Parasitology

31 July 2017

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31 July 2017

126

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31 July 2017

129-142

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31 July 2017

2

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Optical and radiocarbon dating at Jinmium rock shelter in northern Australia

31 July 2017

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Effects of interruption of apicoplast function on malaria infection, development, and transmission

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Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum

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Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I.

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Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum

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Growth of Toxoplasma gondii is inhibited by aryloxyphenoxypropionate herbicides targeting acetyl-CoA carboxylase

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Subcellular localization of acetyl-CoA carboxylase in the apicomplexan parasite Toxoplasma gondii

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Localization and characterization of two structurally different forms of acetyl-CoA carboxylase in young pea leaves, of which one is sensitive to aryloxyphenoxypropionate herbicides

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An isoleucine/leucine residue in the carboxyltransferase domain of acetyl-CoA carboxylase is critical for interaction with aryloxyphenoxypropionate and cyclohexanedione inhibitors

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Dominant mutations causing alterations in acetyl-coenzyme A carboxylase confer tolerance to cyclohexanedione and aryloxyphenoxypropionate herbicides in maize

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Lipid biosynthesis as a target for antibacterial agents

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Specialized fatty acid synthesis in African trypanosomes: myristate for GPI anchors

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Fatty acid synthesis in African trypanosomes: a solution to the myristate mystery.

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Protein trafficking to the plastid of Plasmodium falciparum is via the secretory pathway

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Molecular analysis of a Type I fatty acid synthase in Cryptosporidium parvum.

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Ultrastructural analysis of the sporozoite of Cryptosporidium parvum

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Cryptosporidium parvum appears to lack a plastid genome

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Thiolactomycin, a new antibiotic. I. Taxonomy of the producing organism, fermentation and biological properties.

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A mechanism of drug action revealed by structural studies of enoyl reductase

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Molecular basis of triclosan activity

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Structural and physiological features of sterols necessary to satisfy bulk membrane and sparking requirements in yeast sterol auxotrophs

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Growth support and metabolism of phytosterols inParamecium tetraurelia.

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A protein kinase antigenically related to pp60v-src possibly involved in yeast cell cycle control: positive in vivo regulation by sterol

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Sterols of Trypanosomidae

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The sterols of Trypanosoma cruzi and Crithidia fasciculata

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Sterols of Leishmania species. Implications for biosynthesis

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Effects of ketoconazole on sterol biosynthesis by Trypanosoma cruzi epimastigotes

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Sterol composition and biosynthesis in Trypanosoma cruzi amastigotes

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Receptors for the host low density lipoproteins on the hemoflagellate Trypanosoma brucei: purification and involvement in the growth of the parasite

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Exogenous and endogenous sources of sterols in the culture-adapted procyclic trypomastigotes of Trypanosoma brucei

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Cloning and heterologous expression of the Trypanosoma brucei lanosterol synthase gene.

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Effect of the allylamine antifungal drug SF 86-327 on the growth and sterol synthesis of Leishmania mexicana mexicana promastigotes

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Alterations induced by the antifungal compounds ketoconazole and terbinafine in Leishmania

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Naturally azole-resistant Leishmania braziliensis promastigotes are rendered susceptible in the presence of terbinafine: comparative study with azole-susceptible Leishmania mexicana promastigotes

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Antiproliferative synergism of the allylamine SF 86-327 and ketoconazole on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi

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Ultrastructural alterations induced by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi

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Experimental chemotherapy with combinations of ergosterol biosynthesis inhibitors in murine models of Chagas' disease

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Effects of ketoconazole on growth and sterol biosynthesis of Leishmania mexicana promastigotes in culture☆

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Sterols of ketoconazole-inhibited Leishmania mexicana mexicana promastigotes

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Effects of ketoconazole on sterol biosynthesis by Leishmania mexicana mexicana amastigotes in murine macrophage tumor cells

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Effects of antimycotic azoles on growth and sterol biosynthesis of Leishmania promastigotes

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The activity of ketoconazole and other azoles against Trypanosoma cruzi: biochemistry and chemotherapeutic action in vitro

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Antiproliferative effects and mechanism of action of ICI 195,739, a novel bis-triazole derivative, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi

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Cure of short- and long-term experimental Chagas' disease using D0870

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Antiproliferative effects and mechanism of action of SCH 56592 against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies.

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Activities of the triazole derivative SCH 56592 (posaconazole) against drug-resistant strains of the protozoan parasite Trypanosoma (Schizotrypanum) cruzi in immunocompetent and immunosuppressed murine hosts

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Effects of an azasterol inhibitor of sterol 24-transmethylation on sterol biosynthesis and growth of Leishmania donovani promastigotes

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Ultrastructural alterations in Trypanosoma (Schizotrypanum) cruzi induced by Delta(24(25)) sterol methyl transferase inhibitors and their combinations with ketoconazole

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Transport of sterols to the plasma membrane of leek seedlings

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Lipid trafficking and sorting: how cholesterol is filling gaps

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Altered lipid composition and enzyme activities of plasma membranes from Trypanosoma (Schizotrypanum) cruzi epimastigotes grown in the presence of sterol biosynthesis inhibitors

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Impairment of sterol biosynthesis leads to phosphorus and calcium accumulation in Leishmania acidocalcisomes

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Isolation of genes mediating resistance to inhibitors of nucleoside and ergosterol metabolism in Leishmania by overexpression/selection.

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Sterols in membranes: growth characteristics and membrane properties of Mycoplasma capricolum cultured on cholesterol and lanosterol

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Utilization and metabolism of methyl-sterol derivatives in the yeast mutant strain GL7

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The structural requirements of sterols for membrane function in Saccharomyces cerevisiae

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Synergism in vitro of lovastatin and miconazole as anti-leishmanial agents

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Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies

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Utilization of leucine and acetate as carbon sources for sterol and fatty acid biosynthesis by Old and New World Leishmania species, Endotrypanum monterogeii and Trypanosoma cruzi

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The biosynthetic incorporation of the intact leucine skeleton into sterol by the trypanosomatid Leishmania mexicana.

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7 January 2021

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31 July 2017

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