The extended cleavage specificity of human thrombin (Q34181932)

31 July 2017

The extended cleavage specificity of human thrombin (English)

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31 July 2017

Michael Thorpe

3

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author name string

Maike Gallwitz

series ordinal

1

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31 July 2017

Mattias Enoksson

series ordinal

2

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31 July 2017

Lars Hellman

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4

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31 July 2017

language of work or name

English

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publication date

27 February 2012

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31 July 2017

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31 July 2017

7

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31 July 2017

2

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31 July 2017

e31756

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Creative Commons Attribution 4.0 International

31 July 2017

start time

27 February 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3288055/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The effects of exosite occupancy on the substrate specificity of thrombin

5 July 2018

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The extended substrate specificity of the human mast cell chymase reveals a serine protease with well-defined substrate recognition profile

5 July 2018

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Extended cleavage specificity of mMCP-1, the major mucosal mast cell protease in mouse-high specificity indicates high substrate selectivity

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The extended cleavage specificity of the rodent beta-chymases rMCP-1 and mMCP-4 reveal major functional similarities to the human mast cell chymase

5 July 2018

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Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substrate

5 July 2018

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Methods for mapping protease specificity

5 July 2018

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An overview of the structure and function of thrombin

5 July 2018

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Molecular recognition mechanisms of thrombin

5 July 2018

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Substrate specificity of the Escherichia coli outer membrane protease OmpT.

5 July 2018

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The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia

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Extended substrate specificity of rat mast cell protease 5, a rodent alpha-chymase with elastase-like primary specificity

5 July 2018

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Human and mouse proteases: a comparative genomic approach

5 July 2018

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Identification of Peptide Substrates for Human MMP-11 (Stromelysin-3) Using Phage Display

5 July 2018

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The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury: deleterious or protective?

5 July 2018

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Substrate specificity of human kallikrein 2 (hK2) as determined by phage display technology

5 July 2018

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Rat mast cell protease 4 is a beta-chymase with unusually stringent substrate recognition profile

5 July 2018

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5 July 2018

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Thrombin signalling and protease-activated receptors

5 July 2018

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Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin

5 July 2018

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Definition and redesign of the extended substrate specificity of granzyme B.

5 July 2018

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Site-specific dissection of substrate recognition by thrombin

5 July 2018

1 reference

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Dissociation of heparin-dependent thrombin and factor Xa inhibitory activities of antithrombin-III by mutations in the reactive site

5 July 2018

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5 July 2018

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Protease inhibitors influence the direction of neurite outgrowth

5 July 2018

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Thrombin is a Na(+)-activated enzyme

5 July 2018

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Serine Proteases: Structure and Mechanism of Catalysis

5 July 2018

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Involvement of thrombin and mitogen-activated protein kinase pathways in hemorrhagic brain injury.

5 July 2018

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Thrombin potently enhances swelling-sensitive glutamate efflux from cultured astrocytes.

28 October 2018

1 reference

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Thrombin in ischemic neuronal death

28 October 2018

1 reference

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Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity

28 October 2018

1 reference

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Thrombin downregulates muscle acetylcholine receptors via an IP3 signaling pathway by activating its G-protein-coupled protease-activated receptor-1.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288055

Thrombin Inhibits NMDA‐Mediated Nociceptive activity in the Mouse: Possible Mediation by Endothelin

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288055

Mapping of the catalytic groove preferences of factor Xa reveals an inadequate selectivity for its macromolecule substrates.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288055

Construction and characterization of thrombin-resistant variants of recombinant human protein S.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288055

Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G-250 and R-250.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288055

The role of Glu(192) in the allosteric control of the S(2)' and S(3)' subsites of thrombin

28 October 2018

1 reference

12 December 2020

Roles of thermal instability and proteolytic cleavage in regulation of activated thrombin-activable fibrinolysis inhibitor

1 reference

12 December 2020

Thrombin specificity. Requirement for apolar amino acids adjacent to the thrombin cleavage site of polypeptide substrate

1 reference

12 December 2020

Effect of plasminogen activator (urokinase), plasmin, and thrombin on glycoprotein and collagenous components of basement membrane

1 reference

12 December 2020

Thrombin-induced growth cone collapse: involvement of phospholipase A(2) and eicosanoid generation

1 reference

12 December 2020

Comparative Kinetic Behaviour of Thrombin, Plasmin and Trypsin toward Synthetic Substrates

1 reference

12 December 2020

Expression profile of novel members of the rat mast cell protease (rMCP)-2 and (rMCP)-8 families, and functional analyses of mouse mast cell protease (mMCP)-8

1 reference

12 December 2020

Potentiation of NMDA receptor function by the serine protease thrombin

1 reference

12 December 2020

Highly sensitive peptide-4-methylcoumaryl-7-amide substrates for blood-clotting proteases and trypsin

1 reference

12 December 2020

Sites of nidogen cleavage by proteases involved in tissue homeostasis and remodelling

1 reference

12 December 2020

Study of the Specificity of Thrombin with Tripeptidyl-p-nitroanilide Substrates

1 reference

12 December 2020

Thrombin Glu-39 restricts the P'3 specificity to nonacidic residues

1 reference

12 December 2020

Site-directed mutagenesis of the reactive center (serine 394) of antithrombin III

1 reference

12 December 2020

The action of thrombin on peptide p-nitroanilide substrates. Substrate selectivity and examination of hydrolysis under different reaction conditions

1 reference

12 December 2020

Characterization of the P2' and P3' specificities of thrombin using fluorescence-quenched substrates and mapping of the subsites by mutagenesis

1 reference

12 December 2020

Globular domains 4/5 of the laminin alpha3 chain mediate deposition of precursor laminin 5

1 reference

12 December 2020

Thrombin specificity. Selective cleavage of antibody light chains at the joints of variable with joining regions and joining with constant regions

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0031756

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DOI

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31 July 2017

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31 July 2017

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