The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity (Q34187025)

31 July 2017

title

The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity (English)

1 reference

31 July 2017

1 reference

7

Vilhelm A Bohr

1 reference

31 July 2017

Jeanine A Harrigan

1

1 reference

31 July 2017

Patricia L Opresko

2

1 reference

31 July 2017

Cayetano von Kobbe

3

1 reference

31 July 2017

Padmini S Kedar

4

1 reference

31 July 2017

Rajendra Prasad

5

1 reference

31 July 2017

Samuel H Wilson

6

1 reference

31 July 2017

language of work or name

English

0 references

publication date

27 March 2003

1 reference

Journal of Biological Chemistry

31 July 2017

number of pages

10

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

31 July 2017

volume

278

1 reference

31 July 2017

issue

25

1 reference

31 July 2017

page(s)

22686-22695

1 reference

Genetic analysis of ageing: role of oxidative damage and environmental stresses.

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Roles of the Werner syndrome protein in pathways required for maintenance of genome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Mutator phenotype of Werner syndrome is characterized by extensive deletions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Homologous recombination resolution defect in werner syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Unwinding the molecular basis of the Werner syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Werner and Bloom helicases are involved in DNA repair in a complementary fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Response of base excision repair enzymes to complex DNA lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

21 January 2018

Life without DNA repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Suppression of spontaneous mutagenesis in human cells by DNA base excision-repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Involvement of poly(ADP-ribose) polymerase in base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

A role for p53 in base excision repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Replication protein A stimulates long patch DNA base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Werner protein recruits DNA polymerase delta to the nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Functional interaction between the Werner Syndrome protein and DNA polymerase delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Functional and physical interaction between WRN helicase and human replication protein A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Substrate binding by human apurinic/apyrimidinic endonuclease indicates a Briggs-Haldane mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Enzymatic and DNA binding properties of purified WRN protein: high affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Direct interaction between mammalian DNA polymerase beta and proliferating cell nuclear antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Specific interaction of DNA polymerase beta and DNA ligase I in a multiprotein base excision repair complex from bovine testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

DNA polymerase beta -mediated long patch base excision repair. Poly(ADP-ribose)polymerase-1 stimulates strand displacement DNA synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Appendix. Gel kinetic analysis of polymerase fidelity in the presence of multiple enzyme DNA encounters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

The Werner syndrome protein is a DNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

DNA repair and mutagenesis in Werner syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Selective blockage of the 3'-->5' exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Covalent trapping of human DNA polymerase beta by the oxidative DNA lesion 2-deoxyribonolactone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Protein complexes in nucleotide excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

DNA mismatch repair and mutation avoidance pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Weak strand displacement activity enables human DNA polymerase beta to expand CAG/CTG triplet repeats at strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Comparative sequence analysis of ribonucleases HII, III, II PH and D

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Characterization of the human and mouse WRN 3'-->5' exonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

21 January 2018

The 3' 5' exonucleases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Chromosome instability in lymphocytes from a patient with Werner's syndrome is not associated with DNA repair defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Spontaneous and induced chromosomal instability in Werner syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

dNTP binding site in rat DNA polymerase beta revealed by controlled proteolysis and azido photoprobe cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Passing the baton in base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Unwinding of a DNA triple helix by the Werner and Bloom syndrome helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

Werner syndrome protein. II. Characterization of the integral 3' --> 5' DNA exonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213103200

21 January 2018

Identifiers

DOI

10.1074/JBC.M213103200

1 reference

31 July 2017

1 reference