Dictyostelium: an ideal organism for genetic dissection of Ras signalling networks. (Q34189296)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11257439%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

review article

1 reference

title

Dictyostelium: an ideal organism for genetic dissection of Ras signalling networks (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11257439%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11257439%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

J R Chubb

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11257439%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

language of work or name

English

0 references

publication date

1 March 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11257439%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

number of pages

10

1 reference

Biochimica et Biophysica Acta

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11257439%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

1525

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11257439%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11257439%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

page(s)

262-271

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11257439%20AND%20SRC:MED&resulttype=core&format=json

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses

5 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Increasing complexity of Ras signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

1 reference

7 January 2021

The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Ras pathways in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Isolation of ras GTP-binding mutants using an in situ colony-binding assay

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Inhibition of growth factor-induced differentiation of PC12 cells by microinjection of antibody to ras p21

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Signalling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

The GTPase superfamily: a conserved switch for diverse cell functions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Regulation of Ras-mediated signalling: more than one way to skin a cat.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Complex formation between RAS and RAF and other protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Mammalian Ras interacts directly with the serine/threonine kinase Raf

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

In yeast, RAS proteins are controlling elements of adenylate cyclase.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Ras mediates the activation of phospholipase D by v-Src

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Evidence for a Ras/Ral signaling cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Developmental regulation of a Dictyostelium gene encoding a protein homologous to mammalian ras protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Growing and developing Dictyostelium cells express different ras genes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Genome sequence of the nematode C. elegans: a platform for investigating biology

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

The genome sequence of Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

cAMP and cell sorting control the spatial expression of a developmentally essential cell-type-specific ras gene in Dictyostelium

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin-mediated protein degradation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

The Dictyostelium MAP kinase kinase DdMEK1 regulates chemotaxis and is essential for chemoattractant-mediated activation of guanylyl cyclase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

A MAP kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Identification and functional analysis of a developmentally regulated extracellular signal-regulated kinase gene in Dictyostelium discoideum

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Increased conversion of phosphatidylinositol to phosphatidylinositol phosphate in Dictyostelium cells expressing a mutated ras gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Effects of normal and mutant ras genes on inositol lipid metabolism in Dictyostelium

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

A novel Ras-interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

ralGDS family members interact with the effector loop of ras p21.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

The aimless RasGEF is required for processing of chemotactic signals through G-protein-coupled receptors in Dictyostelium.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

DGAP1, a homologue of rasGTPase activating proteins that controls growth, cytokinesis, and development in Dictyostelium discoideum.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Dictyostelium IQGAP-related protein specifically involved in the completion of cytokinesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Dictyostelium RasG is required for normal motility and cytokinesis, but not growth.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Structure and function of the cytoskeleton of a Dictyostelium myosin-defective mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

A novel member of the rho family of small GTP-binding proteins is specifically required for cytokinesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Overexpression of an activated rasG gene during growth blocks the initiation of Dictyostelium development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

The effects of expression of an activated rasG mutation on the differentiation of Dictyostelium

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Dictyostelium myosin I double mutants exhibit conditional defects in pinocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Coronin involved in phagocytosis: dynamics of particle-induced relocalization visualized by a green fluorescent protein Tag

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Inactivation of two Dictyostelium discoideum genes, DdPIK1 and DdPIK2, encoding proteins related to mammalian phosphatidylinositide 3-kinases, results in defects in endocytosis, lysosome to postlysosome transport, and actin cytoskeleton organization

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Overexpression of a novel rho family GTPase, RacC, induces unusual actin-based structures and positively affects phagocytosis in Dictyostelium discoideum

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

A novel cytosolic regulator, Pianissimo, is required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

The Dictyostelium mitogen-activated protein kinase ERK2 is regulated by Ras and cAMP-dependent protein kinase (PKA) and mediates PKA function.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Negative influence of RasG on chemoattractant-induced ERK2 phosphorylation in Dictyostelium

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Comparison of the Dictyostelium rasD and ecmA genes reveals two distinct mechanisms whereby an mRNA may become enriched in prestalk cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Phenotypic changes induced by a mutated ras gene during the development of Dictyostelium transformants

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Ligand-independent reduction of cAMP receptors in Dictyostelium discoideum cells over-expressing a mutated ras gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Expression of an activated rasD gene changes cell fate decisions during Dictyostelium development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Multiple Ras functions can contribute to mammalian cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Wortmannin inhibits insulin-induced Ras and mitogen-activated protein kinase activation related to adipocyte differentiation in 3T3-L1 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

The murine N-ras gene is not essential for growth and development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

All ras proteins are polyisoprenylated but only some are palmitoylated

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Ras and Rap1: two highly related small GTPases with distinct function

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Functional roles for the pleckstrin and Dbl homology regions in the Ras exchange factor Son-of-sevenless

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Understanding Ras: 'it ain't over 'til it's over'.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

Molecular cloning and DNA sequence of a Dictyostelium cDNA encoding a Ran/TC4 related GTP binding protein belonging to the ras superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2801%2900111-8

7 January 2021

10.1016/S0304-4165(01)00111-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11257439%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference