The tempered polymerization of human neuroserpin (Q34193142)

31 July 2017

title

The tempered polymerization of human neuroserpin (English)

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31 July 2017

9

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31 July 2017

Maria Rosalia Mangione

Maria Rosalia Mangione

4

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Mauro Manno

Mauro Manno

10

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Matteo Levantino

Matteo Levantino

5

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Vincenzo Martorana

Vincenzo Martorana

7

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Stefano Ricagno

Stefano Ricagno

3

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author name string

Rosina Noto

1

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31 July 2017

Maria Grazia Santangelo

2

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31 July 2017

Margherita Pezzullo

6

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31 July 2017

Antonio Cupane

8

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31 July 2017

language of work or name

English

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publication date

6 March 2012

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31 July 2017

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31 July 2017

volume

7

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31 July 2017

issue

3

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31 July 2017

page(s)

e32444

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Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

6 March 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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5 July 2018

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Two latent and two hyperstable polymeric forms of human neuroserpin

5 July 2018

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Defining the mechanism of polymerization in the serpinopathies

5 July 2018

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A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with alpha1-antitrypsin deficiency.

5 July 2018

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An analytical solution to the kinetics of breakable filament assembly

5 July 2018

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pH-dependent stability of neuroserpin is mediated by histidines 119 and 138; implications for the control of beta-sheet A and polymerization

5 July 2018

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Neuroserpin polymers activate NF-kappaB by a calcium signaling pathway that is independent of the unfolded protein response.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization

5 July 2018

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The structural basis of serpin polymerization studied by hydrogen/deuterium exchange and mass spectrometry

5 July 2018

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Revisiting the method of cumulants for the analysis of dynamic light-scattering data

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The intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB.

5 July 2018

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Molecular gymnastics: serpin structure, folding and misfolding

5 July 2018

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Neuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer disease

5 July 2018

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5 July 2018

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5 July 2018

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Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB

5 July 2018

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Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum

5 July 2018

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How do proteins avoid becoming too stable? Biophysical studies into metastable proteins

5 July 2018

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Serpin structure, mechanism, and function

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295756

Acyl-enzyme complexes between tissue-type plasminogen activator and neuroserpin are short-lived in vitro

5 July 2018

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Association between conformational mutations in neuroserpin and onset and severity of dementia

5 July 2018

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Mutant Neuroserpin (S49P) that causes familial encephalopathy with neuroserpin inclusion bodies is a poor proteinase inhibitor and readily forms polymers in vitro

5 July 2018

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The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

5 July 2018

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Structure of a serpin-protease complex shows inhibition by deformation

5 July 2018

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Universal Aging Features in the Restructuring of Fractal Colloidal Gels

5 July 2018

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Inactive conformation of the serpin alpha(1)-antichymotrypsin indicates two-stage insertion of the reactive loop: implications for inhibitory function and conformational disease

5 July 2018

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5 July 2018

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Theoretical studies on oscillations in microtubule polymerization

5 July 2018

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Synchronous oscillations in microtubule polymerization

5 July 2018

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Identifiers

DOI

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31 July 2017

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31 July 2017

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