Two New Substrates in Insulin Signaling, IRS5/DOK4 and IRS6/DOK5 (Q34194701)

31 July 2017

Two New Substrates in Insulin Signaling, IRS5/DOK4 and IRS6/DOK5 (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M212430200

30 December 2023

1 reference

intracellular signaling peptides and proteins

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730241

30 December 2023

transport protein

1 reference

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30 December 2023

signal transduction

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730241

30 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M212430200

30 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M212430200

30 December 2023

4

Jongsoon Lee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730241

30 December 2023

author name string

Dongsheng Cai

1

1 reference

31 July 2017

Sirano Dhe-Paganon

2

1 reference

31 July 2017

Peter A. Melendez

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730241

30 December 2023

Steven E. Shoelson

5

1 reference

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30 December 2023

language of work or name

English

0 references

publication date

1 May 2003

1 reference

31 July 2017

11 July 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12730241

full work available at URL

30 December 2023

number of pages

8

1 reference

based on heuristic

inferred from page(s)

http://www.jbc.org/article/S0021925819750431/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730241

https://api.elsevier.com/content/article/PII:S0021925819750431?httpAccept=text/xml

30 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M212430200

https://api.elsevier.com/content/article/PII:S0021925819750431?httpAccept=text/plain

30 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M212430200

https://syndication.highwire.org/content/doi/10.1074/jbc.M212430200

30 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M212430200

Journal of Biological Chemistry

30 December 2023

published in

1 reference

31 July 2017

278

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31 July 2017

25323-25330

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31 July 2017

28

1 reference

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

31 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Role of IRS-2 in insulin and cytokine signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Disruption of IRS-2 causes type 2 diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Domain-dependent function of the rasGAP-binding protein p62Dok in cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Recruitment of Dok-R to the EGF receptor through its PTB domain is required for attenuation of Erk MAP kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Characterization of a novel member of the DOK family that binds and modulates Abl signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Insulin-like growth factor-I receptor internalization regulates signaling via the Shc/mitogen-activated protein kinase pathway, but not the insulin receptor substrate-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

SH2 domains recognize specific phosphopeptide sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

The protein tyrosine phosphatase inhibitor, pervanadate, is a powerful antidiabetic agent in streptozotocin-treated diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

An epidermal growth factor receptor/ret chimera generates mitogenic and transforming signals: evidence for a ret-specific signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

YMXM motifs of IRS-1 define substrate specificity of the insulin receptor kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Insulin regulation of the Ras activation/inactivation cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Tyrosine phosphorylation of p62(Dok) induced by cell adhesion and insulin: possible role in cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

IRS-2 pathways integrate female reproduction and energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212430200

American Journal of Physiology

21 January 2018

8

278

E127

Fantin

2000

1 reference

https://api.crossref.org/works/10.1074/JBC.M212430200

p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

30 December 2023

10

1 reference

https://api.crossref.org/works/10.1074/JBC.M212430200

Pervanadate [peroxide(s) of vanadate] mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase

30 December 2023

25

1 reference

https://api.crossref.org/works/10.1074/JBC.M212430200

Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation

30 December 2023

28

1 reference

https://api.crossref.org/works/10.1074/JBC.M212430200

30 December 2023

Identifiers

1 reference

31 July 2017

1 reference