Modeling chemical interaction profiles: I. Spectral data-activity relationship and structure-activity relationship models for inhibitors and non-inhibitors of cytochrome P450 CYP3A4 and CYP2D6 isozymes (Q34197418)

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scientific article published on 15 March 2012

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English	Modeling chemical interaction profiles: I. Spectral data-activity relationship and structure-activity relationship models for inhibitors and non-inhibitors of cytochrome P450 CYP3A4 and CYP2D6 isozymes	scientific article published on 15 March 2012

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scholarly article

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Europe PubMed Central

2 July 2019

http://europepmc.org/abstract/PMC/6268752

Modeling chemical interaction profiles: I. Spectral data-activity relationship and structure-activity relationship models for inhibitors and non-inhibitors of cytochrome P450 CYP3A4 and CYP2D6 isozymes (English)

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Europe PubMed Central

2 July 2019

http://europepmc.org/abstract/PMC/6268752

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object named as

Weida Tong

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http://europepmc.org/abstract/PMC/6268752

Bruce A. Fowler

12

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Bruce A Fowler

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http://europepmc.org/abstract/PMC/6268752

author name string

Brooks McPhail

1

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http://europepmc.org/abstract/PMC/6268752

Yunfeng Tie

2

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http://europepmc.org/abstract/PMC/6268752

Huixiao Hong

3

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http://europepmc.org/abstract/PMC/6268752

Bruce A Pearce

4

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http://europepmc.org/abstract/PMC/6268752

Laura K Schnackenberg

5

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http://europepmc.org/abstract/PMC/6268752

Weigong Ge

6

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http://europepmc.org/abstract/PMC/6268752

Luis G Valerio

7

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http://europepmc.org/abstract/PMC/6268752

James C Fuscoe

8

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Dan A Buzatu

10

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http://europepmc.org/abstract/PMC/6268752

Jon G Wilkes

11

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http://europepmc.org/abstract/PMC/6268752

Eugene Demchuk

13

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http://europepmc.org/abstract/PMC/6268752

Richard D Beger

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15 March 2012

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http://europepmc.org/abstract/PMC/6268752

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http://europepmc.org/abstract/PMC/6268752

17

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Europe PubMed Central

2 July 2019

http://europepmc.org/abstract/PMC/6268752

3

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http://europepmc.org/abstract/PMC/6268752

3383-3406

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Europe PubMed Central

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http://europepmc.org/abstract/PMC/6268752

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Creative Commons Attribution 4.0 International

15 March 2012

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1 reference

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1 reference

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1 reference

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Trainable structure-activity relationship model for virtual screening of CYP3A4 inhibition.

1 reference

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SAR/QSAR methods in public health practice

1 reference

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Perpetrators of pharmacokinetic drug-drug interactions arising from altered cytochrome P450 activity: a criteria-based assessment.

1 reference

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1 reference

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1 reference

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1 reference

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Use of 13C NMR chemical shift as QSAR/QSPR descriptor

1 reference

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1 reference

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1 reference

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1 reference

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Modeling chemical interaction profiles: II. Molecular docking, spectral data-activity relationship, and structure-activity relationship models for potent and weak inhibitors of cytochrome P450 CYP3A4 isozyme

1 reference

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Enzyme-catalyzed detoxication reactions: mechanisms and stereochemistry

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1 reference

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Overview of enzymes of drug metabolism

1 reference

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Evaluation of atypical cytochrome P450 kinetics with two-substrate models: evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/22421792

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based on heuristic

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Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22421792

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Onset of xenobiotic metabolism in children: toxicological implications

1 reference

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Identifiers

10.3390/MOLECULES17033383

1 reference

Europe PubMed Central

2 July 2019

http://europepmc.org/abstract/PMC/6268752

1 reference

Europe PubMed Central

2 July 2019

http://europepmc.org/abstract/PMC/6268752

1 reference

Europe PubMed Central

2 July 2019

http://europepmc.org/abstract/PMC/6268752

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