A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis (Q34208933)

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English	A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

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Merrie Mosedale

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Merrie Mosedale

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Wimal Pathmasiri

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Wimal Pathmasiri

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Susan J Sumner

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author name string

Rachel J Church

1

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31 July 2017

Hong Wu

2

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31 July 2017

Catherine L Kurtz

6

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31 July 2017

Mathew T Pletcher

7

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31 July 2017

John S Eaddy

8

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31 July 2017

Karamjeet Pandher

9

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31 July 2017

Monica Singer

10

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31 July 2017

Ameesha Batheja

11

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31 July 2017

Paul B Watkins

12

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31 July 2017

Karissa Adkins

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31 July 2017

Alison H Harrill

14

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31 July 2017

publication date

20 May 2014

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31 July 2017

Toxicological Sciences

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31 July 2017

140

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31 July 2017

2

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31 July 2017

481-492

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31 July 2017

Mechanisms of isoniazid-induced idiosyncratic liver injury: emerging role of mitochondrial stress

1 reference

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5 July 2018

Candidate gene polymorphisms in patients with acetaminophen-induced acute liver failure

1 reference

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5 July 2018

The minor allele of the missense polymorphism Ser251Pro in perilipin 2 (PLIN2) disrupts an α-helix, affects lipolysis, and is associated with reduced plasma triglyceride concentration in humans

1 reference

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5 July 2018

Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease

1 reference

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5 July 2018

Direct oxidation and covalent binding of isoniazid to rodent liver and human hepatic microsomes: humans are more like mice than rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168290

5 July 2018

Lipids and lysosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168290

5 July 2018

A mouse diversity panel approach reveals the potential for clinical kidney injury due to DB289 not predicted by classical rodent models

1 reference

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5 July 2018

Mitochondrial roles and cytoprotection in chronic liver injury

1 reference

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5 July 2018

Imputation of single-nucleotide polymorphisms in inbred mice using local phylogeny.

1 reference

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5 July 2018

Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression

1 reference

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5 July 2018

A fresh look at the mechanism of isoniazid-induced hepatotoxicity

1 reference

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5 July 2018

In silico QTL mapping of basal liver iron levels in inbred mouse strains

1 reference

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5 July 2018

Metabolomics of urine for the assessment of microvesicular lipid accumulation in the liver following isoniazid exposure

1 reference

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5 July 2018

Apoptosis and autophagy: Targeting autophagy signalling in cancer cells -'trick or treats'?

1 reference

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5 July 2018

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

1 reference

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5 July 2018

Circulating microRNAs, potential biomarkers for drug-induced liver injury

1 reference

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5 July 2018

Antituberculosis drug-induced hepatotoxicity: concise up-to-date review

1 reference

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5 July 2018

The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics

1 reference

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5 July 2018

Sequence polymorphisms cause many false cis eQTLs

1 reference

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5 July 2018

Genomewide association analysis in diverse inbred mice: power and population structure

1 reference

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5 July 2018

AceView: a comprehensive cDNA-supported gene and transcripts annotation

1 reference

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5 July 2018

Up-regulation of ADRP in fatty liver in human and liver steatosis in mice fed with high fat diet.

1 reference

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5 July 2018

The quantitatively important relationship between homocysteine metabolism and glutathione synthesis by the transsulfuration pathway and its regulation by redox changes

1 reference

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5 July 2018

Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168290

5 July 2018

Steatohepatitis: a tale of two "hits"?

1 reference

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5 July 2018

Alteration in the phosphatidylcholine biosynthesis of rat liver microsomes caused by vitamin B6 deficiency

1 reference

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5 July 2018

The early bactericidal activity of drugs in patients with pulmonary tuberculosis

1 reference

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The induction of a specific form of cytochrome P-450 (P-450j) by fasting

1 reference

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Reduction in VLDL, but not HDL, in plasma of rats deficient in choline.

1 reference

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5 July 2018

Isoniazid-related hepatitis: a U.S. Public Health Service cooperative surveillance study

1 reference

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5 July 2018

Isoniazid and Iproniazid: Activation of Metabolites to Toxic Intermediates in Man and Rat

1 reference

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5 July 2018

Isoniazid-induced cell death is precipitated by underlying mitochondrial complex I dysfunction in mouse hepatocytes

1 reference

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28 October 2018

Isoniazid hepatotoxicity associated with treatment of latent tuberculosis infection: a 7-year evaluation from a public health tuberculosis clinic

1 reference

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28 October 2018

Cellular toxicity of hydrazine in primary rat hepatocytes

1 reference

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28 October 2018

Evaluation of clinical and immunogenetic risk factors for the development of hepatotoxicity during antituberculosis treatment

1 reference

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28 October 2018

Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis

1 reference

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28 October 2018

Apolipoprotein A-IV expression in mouse liver enhances triglyceride secretion and reduces hepatic lipid content by promoting very low density lipoprotein particle expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/24848797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of isoniazid and rifampicin regimens on the liver of tuberculosis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/24848797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Light and electron microscopy studies of the liver in tuberculosis patients receiving rifampin and isoniazid

1 reference

https://pubmed.ncbi.nlm.nih.gov/24848797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Mouse Phenome Project

1 reference

https://pubmed.ncbi.nlm.nih.gov/24848797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of hydrazine in the mechanism of isoniazid hepatotoxicity in rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/24848797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinctive histopathological features that support a diagnosis of cholesterol ester storage disease in liver biopsy specimens

1 reference

https://pubmed.ncbi.nlm.nih.gov/24848797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/TOXSCI/KFU094

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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