Voltage-dependent K(+) channels in pancreatic beta cells: role, regulation and potential as therapeutic targets (Q34209522)

31 July 2017

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title

Voltage-dependent K(+) channels in pancreatic beta cells: role, regulation and potential as therapeutic targets (English)

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31 July 2017

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MacDonald PE

1

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31 July 2017

Wheeler MB

series ordinal

2

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31 July 2017

language of work or name

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27 June 2003

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31 July 2017

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31 July 2017

46

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31 July 2017

8

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31 July 2017

1046-1062

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https://scigraph.springernature.com/pub.10.1007/s00125-003-1159-8

31 July 2017

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cites work

Effects of glucose on the cytosolic ration of reduced/oxidized nicotinamide-adenine dinucleotide phosphate in rat islets of Langerhans

1 reference

12 December 2020

Developmental changes in the functional characteristics and expression of voltage-gated K+ channel currents in rat aortic myocytes

1 reference

12 December 2020

The sulphonylurea receptor may be an ATP-sensitive potassium channel.

1 reference

12 December 2020

The role of plasma membrane K+ and Ca2+ permeabilities for glucose induction of slow Ca2+ oscillations in pancreatic beta-cells

1 reference

12 December 2020

K+ channel and alpha 2-adrenergic effects on glucose-induced Ca2+i surges: aberrant behavior in ob/ob mice

1 reference

12 December 2020

Membrane potential of beta-cells in pancreatic islets.

1 reference

12 December 2020

Isoform-specific localization of voltage-gated K+ channels to distinct lipid raft populations. Targeting of Kv1.5 to caveolae

1 reference

12 December 2020

Multiple products of the Drosophila Shaker gene may contribute to potassium channel diversity

1 reference

12 December 2020

Tetraethylammonium potentiation of insulin release and inhibition of rubidium efflux in pancreatic islets

1 reference

12 December 2020

When it is more than transient neonatal hypoglycemia: hyperinsulinemia--a case study challenge

1 reference

12 December 2020

Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels

1 reference

12 December 2020

Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel

1 reference

12 December 2020

Successful therapy with calcium channel blocker (nifedipine) in persistent neonatal hyperinsulinemic hypoglycemia of infancy.

1 reference

12 December 2020

Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle

1 reference

12 December 2020

Properties of Kv2.1 K+ channels expressed in transfected mammalian cells

1 reference

12 December 2020

Evidence for voltage-gated potassium channel beta-subunits with oxidoreductase motifs in human and rodent pancreatic beta cells

1 reference

12 December 2020

1 reference

12 December 2020

The voltage-gated potassium channel Kv1.3 regulates energy homeostasis and body weight

1 reference

12 December 2020

Molecular cloning and characterization of Kv6.3, a novel modulatory subunit for voltage-gated K(+) channel Kv2.1

1 reference

12 December 2020

6-Amnionicotinamide (6-AN) as a diabetogenic agent. In vitro and in vivo studies in the rat

1 reference

12 December 2020

Charybdotoxin-sensitive K(Ca) channel is not involved in glucose-induced electrical activity in pancreatic β-cells

1 reference

12 December 2020

New modulatory alpha subunits for mammalian Shab K+ channels

1 reference

12 December 2020

Glucagon-like peptide-1 receptor activation antagonizes voltage-dependent repolarizing K(+) currents in beta-cells: a possible glucose-dependent insulinotropic mechanism

1 reference

12 December 2020

A potassium channel beta subunit related to the aldo-keto reductase superfamily is encoded by the Drosophila hyperkinetic locus

1 reference

12 December 2020

Cloning of a novel alpha 1-subunit of the voltage-dependent calcium channel from the beta-cell

1 reference

12 December 2020

Differential Targeting of Shaker-like Potassium Channels to Lipid Rafts

1 reference

12 December 2020

Specificity of tetraethylammonium and quinine for three K channels in insulin-secreting cells

1 reference

12 December 2020

The in vitro inhibition of insulin secretion by diphenylhydantoin

1 reference

12 December 2020

Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo

1 reference

12 December 2020

The beta-cell K(ATP) channel

1 reference

12 December 2020

Glucose decreases Na+,K+-ATPase activity in pancreatic beta-cells. An effect mediated via Ca2+-independent phospholipase A2 and protein kinase C-dependent phosphorylation of the alpha-subunit

1 reference

12 December 2020

Role of voltage- and Ca2(+)-dependent K+ channels in the control of glucose-induced electrical activity in pancreatic B-cells

1 reference

12 December 2020

Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor

1 reference

12 December 2020

Identification of a cytoplasmic domain important in the polarized expression and clustering of the Kv2.1 K+ channel

1 reference

12 December 2020

Glucose-induced decrease in Rb+ permeability in pancreatic β cells

1 reference

12 December 2020

A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning

1 reference

12 December 2020

Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells

1 reference

12 December 2020

Molecular and functional diversity of K+ channels

1 reference

12 December 2020

Kv2.1/Kv9.3, a novel ATP-dependent delayed-rectifier K+ channel in oxygen-sensitive pulmonary artery myocytes

1 reference

12 December 2020

Delayed rectifier K+ channel overexpression in transgenic islets and beta-cells associated with impaired glucose responsiveness.

1 reference

12 December 2020

Regulation of calcium fluxes in rat pancreatic islets: the role of K+ conductance

1 reference

12 December 2020

Beta-adrenergic modulation of cardiac ion channels. Differential temperature sensitivity of potassium and calcium currents

1 reference

12 December 2020

The entero-insular axis in type 2 diabetes--incretins as therapeutic agents

1 reference

12 December 2020

Functional characterization of Kv channel beta-subunits from rat brain

1 reference

12 December 2020

Coupling of voltage-dependent potassium channel inactivation and oxidoreductase active site of Kvbeta subunits.

1 reference

12 December 2020

Single channel studies of the phosphorylation of K+ channels in the squid giant axon. I. Steady-state conditions

1 reference

12 December 2020

Cloning and expression of a novel K+ channel regulatory protein, KChAP

1 reference

12 December 2020

Structure of a voltage-dependent K+ channel beta subunit

1 reference

12 December 2020

Direct interaction of a brain voltage-gated K+ channel with syntaxin 1A: functional impact on channel gating.

1 reference

12 December 2020

Treatment of hyperinsulinaemic hypoglycaemia with nifedipine

1 reference

12 December 2020

Cyclic AMP-modulated potassium channels in murine B cells and their precursors.

1 reference

12 December 2020

Modulation of dihydropyridine-sensitive Ca2+ channels by glucose metabolism in mouse pancreatic beta-cells.

1 reference

12 December 2020

Demonstration of a novel apamin-insensitive calcium-activated K+ channel in mouse pancreatic B cells

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12 December 2020

Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes

1 reference

12 December 2020

The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion

1 reference

12 December 2020

Temperature and redox state dependence of native Kv2.1 currents in rat pancreatic beta-cells.

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12 December 2020

Heteromeric assembly of Kv2.1 with Kv9.3: effect on the state dependence of inactivation

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12 December 2020

Localized calcium influx in pancreatic beta-cells: its significance for Ca2+-dependent insulin secretion from the islets of Langerhans

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12 December 2020

The voltage-gated potassium channels and their relatives

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12 December 2020

Protein phosphorylation and neuronal function.

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12 December 2020

Association and colocalization of K+ channel alpha- and beta-subunit polypeptides in rat brain

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12 December 2020

Enzymes in pancreatic islets that use NADP(H) as a cofactor including evidence for a plasma membrane aldehyde reductase

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12 December 2020

Effects of 4-aminopyridine on insulin secretion and plasma glucose levels in intact and adrenalectomized-chemically sympathectomized mice

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12 December 2020

Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion

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12 December 2020

Identification and localization of K+ channels in the mouse retina

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12 December 2020

Triggering and amplifying pathways of regulation of insulin secretion by glucose

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12 December 2020

Intracellular ATP directly blocks K+ channels in pancreatic B-cells

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12 December 2020

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex

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12 December 2020

Studies Concerning the Hyperglycemic Effects of Diazoxide and Its Mode of Action

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12 December 2020

9-Aminoacridine- and tetraethylammonium-induced reduction of the potassium permeability in pancreatic B-cells. Effects on insulin release and electrical properties

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12 December 2020

Electrical activity in pancreatic islet cells: effect of ions

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12 December 2020

The 25-kDa synaptosome-associated protein (SNAP-25) binds and inhibits delayed rectifier potassium channels in secretory cells.

1 reference

12 December 2020

Molecular determinants of regulated exocytosis

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12 December 2020

Potassium channels and regulation of proliferation of human melanoma cells

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12 December 2020

Voltage-activated calcium and potassium currents in human pancreatic beta-cells

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12 December 2020

Ca(2+)-activated K+ channels from an insulin-secreting cell line incorporated into planar lipid bilayers

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12 December 2020

K+ channel block-induced mammalian neuroblastoma cell swelling: a possible mechanism to influence proliferation.

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12 December 2020

Activation of Ca(2+)-dependent K(+) channels contributes to rhythmic firing of action potentials in mouse pancreatic beta cells

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12 December 2020

Beta-adrenergic modulation of K+ current in human T lymphocytes

1 reference

12 December 2020

Importance of nonionic signals for glucose-induced biphasic insulin secretion

1 reference

12 December 2020

Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila

1 reference

12 December 2020

Evidence that glucose-induced electrical activity in rat pancreatic beta-cells does not require KATP channel inhibition

1 reference

12 December 2020

Blockage of voltage-gated K+ channels inhibits adhesion and proliferation of hepatocarcinoma cells

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12 December 2020

Molecular basis of hypoxia-induced pulmonary vasoconstriction: role of voltage-gated K+ channels

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12 December 2020

Calcium and delayed potassium currents in mouse pancreatic beta-cells under voltage-clamp conditions.

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12 December 2020

The expression and regulation of depolarization-activated K+ channels in the insulin-secreting cell line INS-1.

1 reference

12 December 2020

Single delayed rectifier channels in frog atrial cells. Effects of beta-adrenergic stimulation

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12 December 2020

Cloning of the alpha 1 subunit of a voltage-dependent calcium channel expressed in pancreatic beta cells

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12 December 2020

Modes of regulation of shab K+ channel activity by the Kv8.1 subunit.

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12 December 2020

Electrical responses of pancreatic islet cells to secretory stimuli

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12 December 2020

Cytosolic ratios of free [NADPH]/[NADP+] and [NADH]/[NAD+] in mouse pancreatic islets, and nutrient-induced insulin secretion

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12 December 2020

Electrophysiology of stimulus-secretion coupling in human beta-cells

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12 December 2020

Cloning and tissue distribution of two new potassium channel alpha-subunits from rat brain

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12 December 2020

Voltage noise measurements across the pancreatic beta-cell membrane: calcium channel characteristics

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12 December 2020

The succinate mechanism of insulin release

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12 December 2020

Failure of 6-aminonicotinamide to inhibit the potentiating effect of leucine and arginine on glucose-induced insulin release in vitrol

1 reference

12 December 2020

Functional and molecular aspects of voltage-gated K+ channel beta subunits

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12 December 2020

Differential expression of voltage-gated K+ channel subunits in adult rat heart. Relation to functional K+ channels?

1 reference

12 December 2020

The components of membrane conductance in the giant axon of Loligo

1 reference

12 December 2020

Syntaxin 1A binds to the cytoplasmic C terminus of Kv2.1 to regulate channel gating and trafficking

1 reference

12 December 2020

The novel imidazoline compound BL11282 potentiates glucose-induced insulin secretion in pancreatic beta-cells in the absence of modulation of K(ATP) channel activity.

1 reference

12 December 2020

Demonstration of A-currents in pancreatic islet cells.

1 reference

12 December 2020

Molecular basis of cardiac potassium channel stimulation by protein kinase A

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12 December 2020

Regulation of fast inactivation of cloned mammalian IK(A) channels by cysteine oxidation.

1 reference

12 December 2020

Genetic and Voltage-clamp Analysis of a Drosophila Potassium Channel

1 reference

12 December 2020

Mutations in the Kv beta 2 binding site for NADPH and their effects on Kv1.4.

1 reference

12 December 2020

Role of apoptosis in pancreatic beta-cell death in diabetes

1 reference

12 December 2020

A new hypoglycemic agent, JTT-608, evokes protein kinase A-mediated Ca(2+) signaling in rat islet beta-cells: strict regulation by glucose, link to insulin release, and cooperation with glucagon-like peptide-1(7-36)amide and pituitary adenylate [...]

1 reference

12 December 2020

Shaker K+ channel beta subunits belong to an NAD(P)H-dependent oxidoreductase superfamily.

1 reference

12 December 2020

Expression and function of pancreatic beta-cell delayed rectifier K+ channels. Role in stimulus-secretion coupling

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12 December 2020

Modulation of an inactivating human cardiac K+ channel by protein kinase C.

1 reference

12 December 2020

Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion

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12 December 2020

Nerve growth factor regulates the abundance and distribution of K+ channels in PC12 cells

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12 December 2020

Signal transduction mechanisms in nutrient-induced insulin secretion

1 reference

12 December 2020

Comparison of the Inhibitory Effects of Diphenylhydantoin and Diazoxide Upon Insulin Secretion from the Isolated Perfused Pancreas

1 reference

12 December 2020

Modulation by protein kinase A of a cloned rat brain potassium channel expressed in Xenopus oocytes.

1 reference

12 December 2020

Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion

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12 December 2020

13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)

1 reference

12 December 2020

O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor

1 reference

12 December 2020

Effects of external tetraethylammonium ions and quinine on delayed rectifying K+ channels in mouse pancreatic beta-cells

1 reference

12 December 2020

Glucose- and arginine-induced insulin secretion by human pancreatic beta-cells: the role of HERG K(+) channels in firing and release

1 reference

12 December 2020

Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells

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12 December 2020

Shaker encodes a family of putative potassium channel proteins in the nervous system of Drosophila

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12 December 2020

D-Glucose inhibits potassium efflux from pancreatic islet cells

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12 December 2020

Glucose-induced electrical activity in pancreatic islet cells

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12 December 2020

Activation, but not inhibition, by glucose of Ca2+-dependent K+ permeability in the rat pancreatic B-cell

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12 December 2020

Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7.

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12 December 2020

Glucose dependent K+-channels in pancreatic beta-cells are regulated by intracellular ATP.

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12 December 2020

Insulin-lowering medications in polycystic ovary syndrome

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12 December 2020

Redox status in the control of pulmonary vascular tone.

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12 December 2020

Ion channels in the immune system as targets for immunosuppression

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12 December 2020

Synaptosome-associated protein of 25 kilodaltons modulates Kv2.1 voltage-dependent K(+) channels in neuroendocrine islet beta-cells through an interaction with the channel N terminus

1 reference

12 December 2020

Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.

1 reference

12 December 2020

Physiology of EAG K+ channels

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12 December 2020

Functional interaction of syntaxin and SNAP-25 with voltage-sensitive L- and N-type Ca2+ channels.

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12 December 2020

Regulation of a heart potassium channel by protein kinase A and C

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12 December 2020

Imidazolines and pancreatic hormone secretion.

1 reference

12 December 2020

Characterization of a Ca2+-activated K+ current in insulin-secreting murine betaTC-3 cells

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12 December 2020

Delayed rectifying and calcium-activated K+ channels and their significance for action potential repolarization in mouse pancreatic beta-cells

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12 December 2020

Expression of a cloned rat brain potassium channel in Xenopus oocytes

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12 December 2020

Cloning and expression of the human kv4.3 potassium channel

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12 December 2020

Inhibition of ATP-regulated K+ channels precedes depolarization-induced increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells.

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12 December 2020

Effect of calcium antagonists on reactive hypoglycemia associated with hyperinsulinemia

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12 December 2020

Modulation of the inactivation of voltage-dependent potassium channels by cAMP.

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12 December 2020

Kv2.1 and electrically silent Kv6.1 potassium channel subunits combine and express a novel current

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12 December 2020

K+ channels: generating excitement in pancreatic beta-cells

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12 December 2020

Immunological identification and characterization of a delayed rectifier K+ channel polypeptide in rat brain

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12 December 2020

A minimum of fuel is necessary for tolbutamide to mimic the effects of glucose on electrical activity in pancreatic beta-cells.

1 reference

12 December 2020

KCNQ potassium channels: physiology, pathophysiology, and pharmacology

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12 December 2020

Electrical activity in pancreatic islet cells

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12 December 2020

Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion.

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12 December 2020

Kv beta subunit oxidoreductase activity and Kv1 potassium channel trafficking.

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12 December 2020

A novel targeting signal for proximal clustering of the Kv2.1 K+ channel in hippocampal neurons.

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12 December 2020

Expression of voltage-gated K+ channels in insulin-producing cells. Analysis by polymerase chain reaction

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12 December 2020

Differential asparagine-linked glycosylation of voltage-gated K+ channels in mammalian brain and in transfected cells.

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12 December 2020

Spatial alterations of Kv channels expression and K(+) currents in post-MI remodeled rat heart

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12 December 2020

RINm5f cells express inactivating BK channels whereas HIT cells express noninactivating BK channels.

1 reference

12 December 2020

Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes

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12 December 2020

The coronary circulation in diabetes: influence of reactive oxygen species on K+ channel-mediated vasodilation

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12 December 2020

Protein kinase A phosphorylation alters Kvbeta1.3 subunit-mediated inactivation of the Kv1.5 potassium channel

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12 December 2020

The export of metabolites from mitochondria and anaplerosis in insulin secretion

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12 December 2020

The voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery

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12 December 2020

Voltage-gated and resting membrane currents recorded from B-cells in intact mouse pancreatic islets.

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12 December 2020

Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells

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12 December 2020

SNAP-25, a SNARE protein, inhibits two types of K channels in esophageal smooth muscle

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12 December 2020

Pancreatic islet cells: electrogenic and electrodiffusional control of membrane potential

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12 December 2020

Differential spatiotemporal expression of K+ channel polypeptides in rat hippocampal neurons developing in situ and in vitro

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12 December 2020

Cloning of a probable potassium channel gene from mouse brain

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12 December 2020

Patch-clamp characterisation of somatostatin-secreting -cells in intact mouse pancreatic islets

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12 December 2020

Modulation of potassium channel gating by coexpression of Kv2.1 with regulatory Kv5.1 or Kv6.1 alpha-subunits.

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12 December 2020

Phosphorylation of the Kv2.1 K+ channel alters voltage-dependent activation.

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12 December 2020

Glucose stimulation of insulin release in the absence of extracellular Ca2+ and in the absence of any increase in intracellular Ca2+ in rat pancreatic islets.

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12 December 2020

Mouse pancreatic beta-cells: tetraethylammonium blockage of the potassium permeability increase induced by depolarization

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12 December 2020

Ion channels and diseases

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12 December 2020

Expression of voltage-dependent K(+) channel genes in mesenteric artery smooth muscle cells.

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12 December 2020

Protein kinase C inhibits Kv1.1 potassium channel function.

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12 December 2020

Phosphorylation of a K+ channel alpha subunit modulates the inactivation conferred by a beta subunit. Involvement of cytoskeleton

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12 December 2020

10.1007/S00125-003-1159-8

Identifiers

DOI

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Dimensions Publication ID

31 July 2017

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