Identification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase λ (Q34213489)

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14 February 2020

title

Identification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase λ (English)

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14 February 2020

7

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1

Jessica A Brown

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14 February 2020

Shanen M Sherrer

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author name string

Lindsey R Pack

2

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14 February 2020

Ajay K Kshetry

4

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14 February 2020

Sean A Newmister

5

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14 February 2020

Jason D Fowler

6

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14 February 2020

Zucai Suo

8

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14 February 2020

language of work or name

English

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publication date

21 September 2010

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Journal of Molecular Biology

14 February 2020

published in

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volume

403

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issue

4

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page(s)

505-515

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describes a project that uses

14 February 2020

ImageQuant

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11 June 2022

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inferred from PubMed Central ID database lookup

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Human DNA polymerase kappa forms nonproductive complexes with matched primer termini but not with mismatched primer termini.

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5 July 2018

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Nonoverlapping functions of DNA polymerases mu, lambda, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo

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The DNA polymerase lambda is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells

5 July 2018

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The L561A substitution in the nascent base-pair binding pocket of RB69 DNA polymerase reduces base discrimination

5 July 2018

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DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: analysis by single-turnover kinetics

5 July 2018

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Structure-function studies of DNA polymerase lambda.

5 July 2018

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DNA polymerase lambda mediates a back-up base excision repair activity in extracts of mouse embryonic fibroblasts

5 July 2018

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A closed conformation for the Pol lambda catalytic cycle.

5 July 2018

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5 July 2018

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Role of base stacking and sequence context in the inhibition of yeast DNA polymerase eta by pyrene nucleotide.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repair

5 July 2018

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5 July 2018

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5 July 2018

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DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change

5 July 2018

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Two novel human and mouse DNA polymerases of the polX family

5 July 2018

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Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

5 July 2018

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DNA polymerase beta: effects of gapped DNA substrates on dNTP specificity, fidelity, processivity and conformational changes

5 July 2018

1 reference

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Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

5 July 2018

1 reference

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Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957559

DNA polymerase beta: structure-fidelity relationship from Pre-steady-state kinetic analyses of all possible correct and incorrect base pairs for wild type and R283A mutant

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957559

Requirement of mammalian DNA polymerase-beta in base-excision repair.

5 July 2018

1 reference

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An induced-fit kinetic mechanism for DNA replication fidelity: direct measurement by single-turnover kinetics

5 July 2018

1 reference

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Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant

5 July 2018

1 reference

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Polymerization fidelity of a replicative DNA polymerase from the hyperthermophilic archaeon Sulfolobus solfataricus P2.

5 July 2018

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Pre-steady-state kinetic characterization of the DinB homologue DNA polymerase of Sulfolobus solfataricus

28 October 2018

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Pre-steady-state kinetic studies of the fidelity and mechanism of polymerization catalyzed by truncated human DNA polymerase lambda

28 October 2018

1 reference

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Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV.

28 October 2018

1 reference

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Use of 2-aminopurine and tryptophan fluorescence as probes in kinetic analyses of DNA polymerase beta

28 October 2018

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DNA polymerase lambda, a novel DNA repair enzyme in human cells.

28 October 2018

1 reference

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dNTP binding to HIV-1 reverse transcriptase and mammalian DNA polymerase beta as revealed by affinity labeling with a photoreactive dNTP analog.

28 October 2018

1 reference

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Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta.

28 October 2018

1 reference

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Yeast DNA polymerase eta utilizes an induced-fit mechanism of nucleotide incorporation

28 October 2018

1 reference

12 December 2020

Pre-steady-state kinetic studies of protein-template-directed nucleotide incorporation by the yeast Rev1 protein

1 reference

12 December 2020

Up-regulation of the fidelity of human DNA polymerase lambda by its non-enzymatic proline-rich domain

1 reference

12 December 2020

DNA polymerase beta conducts the gap-filling step in uracil-initiated base excision repair in a bovine testis nuclear extract.

1 reference

12 December 2020

A specific partner for abasic damage in DNA

1 reference

12 December 2020

DNA polymerase beta: multiple conformational changes in the mechanism of catalysis

1 reference

12 December 2020

Structural insights into DNA polymerase beta deterrents for misincorporation support an induced-fit mechanism for fidelity

1 reference

12 December 2020

A new paradigm for DNA polymerase specificity

1 reference

12 December 2020

10.1016/J.JMB.2010.09.014

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20851705%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20851705%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PubMed publication ID

20851705

1 reference