LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells (Q34214122)

31 July 2017

LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells (English)

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31 July 2017

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James L Figarola

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31 July 2017

Jyotsana Singhal

2

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31 July 2017

Samuel Rahbar

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31 July 2017

Sanjay Awasthi

4

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31 July 2017

Sharad S Singhal

5

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31 July 2017

1 May 2014

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31 July 2017

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31 July 2017

19

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31 July 2017

776-788

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31 July 2017

5

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https://scigraph.springernature.com/pub.10.1007/s10495-014-0974-3

31 July 2017

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Anti-inflammatory effects of the advanced glycation end product inhibitor LR-90 in human monocytes

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Selective induction of heparin-binding epidermal growth factor-like growth factor by methylglyoxal and 3-deoxyglucosone in rat aortic smooth muscle cells. The involvement of reactive oxygen species formation and a possible implication for atherogene

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Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.

5 July 2018

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The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal.

5 July 2018

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The reaction of methylglyoxal with aminoguanidine under physiological conditions and prevention of methylglyoxal binding to plasma proteins.

5 July 2018

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Glyoxal and methylglyoxal levels in diabetic patients: quantitative determination by a new GC/MS method

5 July 2018

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Increased serum levels of the specific advanced glycation end product methylglyoxal-derived hydroimidazolone are associated with retinopathy in patients with type 2 diabetes mellitus.

21 January 2018

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Vascular methylglyoxal metabolism and the development of hypertension

21 January 2018

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Apoptosis of endothelial cells precedes myocyte cell apoptosis in ischemia/reperfusion injury

21 January 2018

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In atherogenesis, the apoptosis of endothelial cell itself could directly induce over-proliferation of smooth muscle cells.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10495-014-0974-3

Methylglyoxal-induced apoptosis of endothelial cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10495-014-0974-3

Telmisartan inhibits methylglyoxal-mediated cell death in human vascular endothelium

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10495-014-0974-3

Methylglyoxal induces apoptosis mediated by reactive oxygen species in bovine retinal pericytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-0974-3

LR-90 a new advanced glycation endproduct inhibitor prevents progression of diabetic nephropathy in streptozotocin-diabetic rats

21 January 2018

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Novel inhibitors of advanced glycation endproducts

21 January 2018

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Novel inhibitors of glycation and AGE formation.

21 January 2018

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A new advanced glycation inhibitor, LR-90, prevents experimental diabetic retinopathy in rats.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10495-014-0974-3

Methylglyoxal mediates vascular inflammation via JNK and p38 in human endothelial cells

21 January 2018

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Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells

21 January 2018

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Methylglyoxal induces apoptosis through oxidative stress-mediated activation of p38 mitogen-activated protein kinase in rat Schwann cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10495-014-0974-3

Methylglyoxal augments intracellular oxidative stress in human aortic endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-0974-3

The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-0974-3

Determination of glyoxal and methylglyoxal in the serum of diabetic patients by MEKC using stilbenediamine as derivatizing reagent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-0974-3

Measurement of methylglyoxal in rat tissues by electrospray ionization mass spectrometry and liquid chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-0974-3

Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype.

21 January 2018

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Vaspin prevents methylglyoxal-induced apoptosis in human vascular endothelial cells by inhibiting reactive oxygen species generation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169289

Modification and inactivation of human Cu,Zn-superoxide dismutase by methylglyoxal

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169289

Free radicals generated during the glycation reaction of amino acids by methylglyoxal. A model study of protein-cross-linked free radicals

28 October 2018

1 reference

12 December 2020

17beta-estradiol inhibits apoptosis of endothelial cells

1 reference

12 December 2020

Influence of methylglyoxal on antioxidant enzymes and oxidative damage

1 reference

12 December 2020

Endothelial cells undergoing apoptosis become proadhesive for nonactivated platelets

1 reference

12 December 2020

10.1007/S10495-014-0974-3

Identifiers

DOI

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31 July 2017

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31 July 2017

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