The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1. (Q46026413)

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scientific article published on 26 April 2013

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English	The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1.	scientific article published on 26 April 2013

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scholarly article

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29 February 2020

The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1 (English)

1 reference

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29 February 2020

type-1 diabetes

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atherosclerosis

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based on heuristic

inferred from title

2

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29 February 2020

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29 February 2020

Helen M. Colhoun

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29 February 2020

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29 February 2020

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29 February 2020

Coenraad Dirk Adriaan Stehouwer

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C D A Stehouwer

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29 February 2020

Casper G. Schalkwijk

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C G Schalkwijk

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29 February 2020

author name string

M G A van Eupen

1

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29 February 2020

N M J Hanssen

5

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29 February 2020

H W M Niessen

6

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29 February 2020

H H Parving

8

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29 February 2020

publication date

26 April 2013

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29 February 2020

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29 February 2020

56

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29 February 2020

1845-1855

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29 February 2020

8

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29 February 2020

https://scigraph.springernature.com/pub.10.1007/s00125-013-2919-8

0 references

Biochemistry and molecular cell biology of diabetic complications

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21 January 2018

Higher plasma levels of advanced glycation end products are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study

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21 January 2018

Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis

1 reference

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21 January 2018

Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2919-8

21 January 2018

The glyoxalase system in health and disease

1 reference

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21 January 2018

Glyoxalase in diabetes, obesity and related disorders

1 reference

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21 January 2018

Methylglyoxal modification of protein. Chemical and immunochemical characterization of methylglyoxal-arginine adducts

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2919-8

21 January 2018

Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2919-8

21 January 2018

Chromatographic quantification of argpyrimidine, a methylglyoxal-derived product in tissue proteins: comparison with pentosidine

1 reference

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21 January 2018

Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins

1 reference

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21 January 2018

Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress

1 reference

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21 January 2018

Methylglyoxal-induced mitochondrial dysfunction in vascular smooth muscle cells

1 reference

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21 January 2018

Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2919-8

21 January 2018

Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress

1 reference

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21 January 2018

High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A

1 reference

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21 January 2018

A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group

1 reference

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21 January 2018

Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo-controlled trial

1 reference

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21 January 2018

Comparative LC-MS/MS profiling of free and protein-bound early and advanced glycation-induced lysine modifications in dairy products

1 reference

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21 January 2018

Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of dia

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2919-8

21 January 2018

Pentosidine - a new biochemical marker in diabetic retinopathy

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2919-8

21 January 2018

Plasma advanced glycation endproduct, methylglyoxal-derived hydroimidazolone is elevated in young, complication-free patients with Type 1 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2919-8

21 January 2018

Degradation products of proteins damaged by glycation, oxidation and nitration in clinical type 1 diabetes.

1 reference

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21 January 2018

Cellular adhesion molecules and cardiovascular disease. Part II. Their association with conventional and emerging risk factors, acute coronary events and cardiovascular risk prediction

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21 January 2018

Soluble adhesion molecules (sICAM-1, sVCAM-1) and selectins (sE selectin, sP selectin, sL selectin) levels in children and adolescents with obesity, hypertension, and diabetes

1 reference

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21 January 2018

Vascular cell adhesion molecule-1 is expressed in human coronary atherosclerotic plaques. Implications for the mode of progression of advanced coronary atherosclerosis

1 reference

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21 January 2018

Soluble vascular cell adhesion molecule-1 and soluble E-selectin are associated with micro- and macrovascular complications in Type 1 diabetic patients.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2919-8

21 January 2018

Synthesis and secretion of tumour necrosis factor-alpha by human monocytic THP-1 cells and chemotaxis induced by human serum albumin derivatives modified with methylglyoxal and glucose-derived advanced glycation endproducts.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2919-8

21 January 2018

Phospholipase A(2) in vascular disease

1 reference

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21 January 2018

Relationship between blood levels of N-carboxymethyl-lysine and pentosidine and the severity of microangiopathy in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2919-8

21 January 2018

Increased serum levels of the specific advanced glycation end product methylglyoxal-derived hydroimidazolone are associated with retinopathy in patients with type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2919-8

21 January 2018

The meaning of serum levels of advanced glycosylation end products in diabetic nephropathy.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2919-8

21 January 2018

Increased serum levels of advanced glycation endproducts predict total, cardiovascular and coronary mortality in women with type 2 diabetes: a population-based 18 year follow-up study

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2919-8

21 January 2018

Type II secretory phospholipase A2: the emerging role of biochemical markers of plaque inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of type 1 diabetes mellitus on the gender difference in coronary artery calcification

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insertion/deletion polymorphism in the angiotensin-l-converting enzyme gene is associated with coronary heart disease in IDDM patients with diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma concentration of C-reactive protein is increased in type I diabetic patients without clinical macroangiopathy and correlates with markers of endothelial dysfunction: evidence for chronic inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct associations of HbA1c and the urinary excretion of pentosidine, an advanced glycosylation end-product, with markers of endothelial function in insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advanced glycation endproducts promote adhesion molecule (VCAM-1, ICAM-1) expression and atheroma formation in normal rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of synthesis and secretion of interleukin 1β in the human monocytic THP-1 cells by human serum albumins modified with methylglyoxal and advanced glycation endproducts

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of arginine modifications in a model system of Nα-tert-butoxycarbonyl (Boc)-arginine with methylglyoxal

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased accumulation of the glycoxidation product Nepsilon-(carboxymethyl)lysine in hearts of diabetic patients: generation and characterisation of a monoclonal anti-CML antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression in vivo of VCAM-1 and E-selectin by the aortic endothelium of normolipemic and hyperlipemic diabetic rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of Nepsilon(carboxymethyl)lysine- and methylglyoxal-modified albumin with endothelial cells and macrophages. Splice variants of RAGE may limit the responsiveness of human endothelial cells to AGEs

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble vascular cell adhesion molecule-1 (VCAM-1) as potential marker of atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glyoxalase System in Clinical Diabetes Mellitus and Correlation with Diabetic Complications

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assay of advanced glycation endproducts (AGEs): surveying AGEs by chromatographic assay with derivatization by 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and application to Nepsilon-carboxymethyl-lysine- and Nepsilon-(1-carboxyethyl)lysine-modi

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection and identification of arginine modifications on methylglyoxal-modified ribonuclease by mass spectrometric analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma concentrations of VCAM-1 and ICAM-1 are elevated in patients with Type 1 diabetes mellitus with microalbuminuria and overt nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620061

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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