β-Cells with relative low HIMP1 overexpression levels in a transgenic mouse line enhance basal insulin production and hypoxia/hypoglycemia tolerance (Q34217750)

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English	β-Cells with relative low HIMP1 overexpression levels in a transgenic mouse line enhance basal insulin production and hypoxia/hypoglycemia tolerance	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

β-Cells with relative low HIMP1 overexpression levels in a transgenic mouse line enhance basal insulin production and hypoxia/hypoglycemia tolerance (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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author name string

Xiaoping Zhang

1

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Europe PubMed Central

PubMed publication ID

31 July 2017

Linda Degenstein

2

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Europe PubMed Central

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31 July 2017

Yun Cao

3

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Europe PubMed Central

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31 July 2017

Jeffrey Stein

4

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Europe PubMed Central

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31 July 2017

Kwame Osei

5

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31 July 2017

Jie Wang

6

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31 July 2017

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publication date

21 March 2012

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Europe PubMed Central

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31 July 2017

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Europe PubMed Central

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31 July 2017

7

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Europe PubMed Central

PubMed publication ID

31 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

e34126

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

copyright license

Creative Commons Attribution 4.0 International

21 March 2012

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April 2022 Public Data File from Crossref

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3309936/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The survival effect of mitochondrial Higd-1a is associated with suppression of cytochrome C release and prevention of caspase activation

1 reference

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28 July 2018

Control of precursor maturation and disposal is an early regulative mechanism in the normal insulin production of pancreatic β-cells

1 reference

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28 July 2018

Type 1 diabetes: etiology, immunology, and therapeutic strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309936

28 July 2018

The hypoxia response pathway and β-cell function.

1 reference

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Banting Lecture 2009: An unfinished journey: molecular pathogenesis to prevention of type 1A diabetes

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Current challenges in islet transplantation.

1 reference

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The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes

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Pancreatic beta cells lack a low glucose and O2-inducible mitochondrial protein that augments cell survival

1 reference

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Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes

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Apoptosis in hypoxic human pancreatic islets correlates with HIF-1alpha expression

1 reference

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High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program

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Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment

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Beta-cell maturation leads to in vitro sensitivity to cytotoxins

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Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes.

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A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse

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Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

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Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation

1 reference

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Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells

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Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulin-dependent diabetes mellitus

1 reference

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The Significance of Basal Insulin Levels in the Evaluation of the Insulin Response to Glucose in Diabetic and Nondiabetic Subjects*

1 reference

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Heterologous introns can enhance expression of transgenes in mice

1 reference

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Prolonged culture in low glucose induces apoptosis of rat pancreatic beta-cells through induction of c-myc.

1 reference

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Point: steady progress and current challenges in clinical islet transplantation

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Factors Influencing the Loss of β-Cell Mass in Islet Transplantation

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Overexpression of glutathione peroxidase with two isoforms of superoxide dismutase protects mouse islets from oxidative injury and improves islet graft function

1 reference

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RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function

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Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes

1 reference

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Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22470529

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Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

1 reference

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Overexpression of catalase provides partial protection to transgenic mouse beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22470529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0034126

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

2012PLoSO...734126Z

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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