Banting Lecture 2009: An unfinished journey: molecular pathogenesis to prevention of type 1A diabetes (Q33750667)

29 July 2017

Banting Lecture 2009: An unfinished journey: molecular pathogenesis to prevention of type 1A diabetes (English)

1 reference

29 July 2017

1

George S Eisenbarth

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PubMed ID

20350969

29 July 2017

language of work or name

English

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publication date

1 April 2010

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29 July 2017

16

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inferred from page(s)

published in

Diabetes

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29 July 2017

59

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29 July 2017

4

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29 July 2017

759-774

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

29 July 2017

start time

30 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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21 June 2018

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Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb Teplizumab preserves insulin production for up to 5 years

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21 June 2018

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21 June 2018

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21 June 2018

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The frequent and conserved DR3-B8-A1 extended haplotype confers less diabetes risk than other DR3 haplotypes.

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Primer: immunity and autoimmunity

21 June 2018

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IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells

21 June 2018

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GAD treatment and insulin secretion in recent-onset type 1 diabetes

21 June 2018

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Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes

21 June 2018

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Innate immunity and intestinal microbiota in the development of Type 1 diabetes

21 June 2018

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Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice

21 June 2018

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Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype: potential for rapid screening

21 June 2018

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21 June 2018

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Conserved T cell receptor alpha-chain induces insulin autoantibodies

21 June 2018

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The accelerator hypothesis and increasing incidence of type 1 diabetes

21 June 2018

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A common nonsynonymous single nucleotide polymorphism in the SLC30A8 gene determines ZnT8 autoantibody specificity in type 1 diabetes

21 June 2018

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Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study

21 June 2018

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Commonality in the genetic control of Type 1 diabetes in humans and NOD mice: variants of genes in the IL-2 pathway are associated with autoimmune diabetes in both species

21 June 2018

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Recurrence of autoreactive antigen-specific CD4+ T cells in autoimmune diabetes after pancreas transplantation.

21 June 2018

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Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire

21 June 2018

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The lack of anti-idiotypic antibodies, not the presence of the corresponding autoantibodies to glutamate decarboxylase, defines type 1 diabetes

21 June 2018

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Trends in high-risk HLA susceptibility genes among Colorado youth with type 1 diabetes

21 June 2018

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Clinical implications of a molecular genetic classification of monogenic beta-cell diabetes

21 June 2018

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Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes

21 June 2018

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Syndromes of ketosis-prone diabetes mellitus

21 June 2018

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The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

21 June 2018

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HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families

21 June 2018

1 reference

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Autoantibodies to IA-2beta improve diabetes risk assessment in high-risk relatives.

21 June 2018

1 reference

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Do the peptide-binding properties of diabetogenic class II molecules explain autoreactivity?

21 June 2018

1 reference

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Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

21 June 2018

1 reference

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The replication of beta cells in normal physiology, in disease and for therapy

21 June 2018

1 reference

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Accepting clocks that tell time poorly: fluid-phase versus standard ELISA autoantibody assays

21 June 2018

1 reference

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Risk alleles for multiple sclerosis identified by a genomewide study

21 June 2018

1 reference

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Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis

21 June 2018

1 reference

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Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity

21 June 2018

1 reference

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Modulation of Aire regulates the expression of tissue-restricted antigens

21 June 2018

1 reference

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Moving towards efficient therapies in type 1 diabetes: to combine or not to combine?

21 June 2018

1 reference

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TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat

21 June 2018

1 reference

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Pre-type 1 diabetes dysmetabolism: maximal sensitivity achieved with both oral and intravenous glucose tolerance testing

21 June 2018

1 reference

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T1DBase: integration and presentation of complex data for type 1 diabetes research

21 June 2018

1 reference

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Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

21 June 2018

1 reference

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Analysis of the type 2 diabetes gene, TCF7L2, in 13,795 type 1 diabetes cases and control subjects

21 June 2018

1 reference

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Extreme genetic risk for type 1A diabetes

21 June 2018

1 reference

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Defective regulatory and effector T cell functions in patients with FOXP3 mutations.

21 June 2018

1 reference

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Timing of initial exposure to cereal grains and the risk of wheat allergy

21 June 2018

1 reference

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Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.

21 June 2018

1 reference

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TGF-beta signaling is required for the function of insulin-reactive T regulatory cells

21 June 2018

1 reference

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Multi-SNP analysis of MHC region: remarkable conservation of HLA-A1-B8-DR3 haplotype

21 June 2018

1 reference

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Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs

21 June 2018

1 reference

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Progression to type 1 diabetes in islet cell antibody-positive relatives in the European Nicotinamide Diabetes Intervention Trial: the role of additional immune, genetic and metabolic markers of risk

21 June 2018

1 reference

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Clinical review: Type 1 diabetes-associated autoimmunity: natural history, genetic associations, and screening

21 June 2018

1 reference

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Advances in pancreatic islet transplantation in humans

21 June 2018

1 reference

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Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

21 June 2018

1 reference

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Type 1 diabetes genes and pathways shared by humans and NOD mice

21 June 2018

1 reference

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Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide

21 June 2018

1 reference

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Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

21 June 2018

1 reference

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21 June 2018

1 reference

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The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice

21 June 2018

1 reference

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Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells

21 June 2018

1 reference

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Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes

21 June 2018

1 reference

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Autoimmune polyglandular syndrome Type 2: the tip of an iceberg?

21 June 2018

1 reference

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Targeted disruption of the IA-2beta gene causes glucose intolerance and impairs insulin secretion but does not prevent the development of diabetes in NOD mice.

21 June 2018

1 reference

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Autoimmune polyendocrine syndromes

21 June 2018

1 reference

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A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

21 June 2018

1 reference

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Development of autoimmune diabetes in glutamic acid decarboxylase 65 (GAD65) knockout NOD mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Early Infant Feeding and Risk of Developing Type 1 Diabetes–Associated Autoantibodies

21 June 2018

1 reference

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Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Influenza virus-induced dendritic cell maturation is associated with the induction of strong T cell immunity to a coadministered, normally nonimmunogenic protein

21 June 2018

1 reference

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Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice

21 June 2018

1 reference

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Projection of an immunological self shadow within the thymus by the aire protein

21 June 2018

1 reference

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The effect of infections on susceptibility to autoimmune and allergic diseases

21 June 2018

1 reference

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Autoimmune adrenocortical failure in Norway autoantibodies and human leukocyte antigen class II associations related to clinical features

21 June 2018

1 reference

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Type 1 diabetes: new perspectives on disease pathogenesis and treatment

21 June 2018

1 reference

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Type 1 diabetes environmental factors and correspondence analysis of HLA class II genes in the Yemenite Jewish community in Israel

21 June 2018

1 reference

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Rapid assays for detection of anti-islet autoantibodies: implications for organ donor screening

21 June 2018

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A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes

21 June 2018

1 reference

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Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

21 June 2018

1 reference

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Immunologic "vaccination" for the prevention of autoimmune diabetes (type 1A).

21 June 2018

1 reference

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T cell receptor restriction of diabetogenic autoimmune NOD T cells

21 June 2018

1 reference

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The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Newborn screening for HLA markers associated with IDDM: diabetes autoimmunity study in the young (DAISY).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Analysis of MHC class II antigens in Japanese IDDM by a novel HLA-typing method, hybridization protection assay

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Extended major histocompatibility complex haplotypes in type I diabetes mellitus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Addison's disease--clinical studies. A report fo 108 cases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Type I diabetes mellitus. A chronic autoimmune disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

The Immunobiology of T Cells with Invariant gammadelta Antigen Receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Induction of type I diabetes by Kilham's rat virus in diabetes-resistant BB/Wor rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Continuous glucose monitoring in type 1 diabetes mellitus.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Induction of anti-whole GAD65 reactivity in vivo results in disease suppression in type 1 diabetes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Treatment of Graves' disease with rituximab specifically reduces the production of thyroid stimulating autoantibodies.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Presence of diabetic ketoacidosis at diagnosis of diabetes mellitus in youth: the Search for Diabetes in Youth Study

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

High incidence of type 1 diabetes mellitus during or shortly after treatment with pegylated interferon alpha for chronic hepatitis C virus infection.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Insulin resistance and progression to type 1 diabetes in the European Nicotinamide Diabetes Intervention Trial (ENDIT).

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Further evidence of a primary, causal association of the PTPN22 620W variant with type 1 diabetes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Omega-3 polyunsaturated fatty acid intake and islet autoimmunity in children at increased risk for type 1 diabetes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Incidence of diabetes in youth in the United States

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

International trial of the Edmonton protocol for islet transplantation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Successful bone marrow transplantation for IPEX syndrome after reduced-intensity conditioning.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Conserved extended haplotypes discriminate HLA-DR3-homozygous Basque patients with type 1 diabetes mellitus and celiac disease.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

An immunologic homunculus for type 1 diabetes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial--Type 1.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Dietary manipulation of beta cell autoimmunity in infants at increased risk of type 1 diabetes: a pilot study

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Insulin resistance is a risk factor for progression to type 1 diabetes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY).

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Clinical characteristics of children diagnosed with type 1 diabetes through intensive screening and follow-up

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Isolation of enterovirus strains from children with preclinical Type 1 diabetes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

IA-2 is not required for the development of diabetes in NOD mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

CD4+CD25+ regulatory T cells generated in response to insulin B:9-23 peptide prevent adoptive transfer of diabetes by diabetogenic T cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Diabetes Antibody Standardization Program: First Assay Proficiency Evaluation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

A sensitive non-isotopic assay for GAD65 autoantibodies

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

A missing link in the hygiene hypothesis?

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

Autoantibodies against Type I Interferons as an Additional Diagnostic Criterion for Autoimmune Polyendocrine Syndrome Type I

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844823

On the pathogenicity of autoantigen-specific T-cell receptors

30 October 2018

1 reference

12 December 2020

1 reference

12 December 2020

Prevalence of autoantibody-negative diabetes is not rare at all ages and increases with older age and obesity

1 reference

12 December 2020

Possible relevance of alpha lipoic acid contained in a health supplement in a case of insulin autoimmune syndrome

1 reference

12 December 2020

The role of the IDDM2 locus in the susceptibility of UK APS1 subjects to type 1 diabetes mellitus

1 reference

12 December 2020

The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice

1 reference

12 December 2020

Refinement of the Iddm4 diabetes susceptibility locus reveals TCRVbeta4 as a candidate gene

1 reference

12 December 2020

To boldly go--or to go too boldly? The accelerator hypothesis revisited

1 reference

12 December 2020

Altered B:9-23 insulin, when administered intranasally with cholera toxin adjuvant, suppresses the expression of insulin autoantibodies and prevents diabetes

1 reference

12 December 2020

HLA-DPB1*0402 protects against type 1A diabetes autoimmunity in the highest risk DR3-DQB1*0201/DR4-DQB1*0302 DAISY population

1 reference

12 December 2020

Continuous home monitoring of glucose: improved glycemic control with real-life use of continuous glucose sensors in adult subjects with type 1 diabetes

1 reference

12 December 2020

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice

1 reference

12 December 2020

Combined insulin B:9-23 self-peptide and polyinosinic-polycytidylic acid accelerate insulitis but inhibit development of diabetes by increasing the proportion of CD4+Foxp3+ regulatory T cells in the islets in non-obese diabetic mice

1 reference

12 December 2020

The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes

1 reference

12 December 2020

Interferon-alpha as a mediator of polyinosinic:polycytidylic acid-induced type 1 diabetes

1 reference

12 December 2020

Mortality in childhood-onset type 1 diabetes: a population-based study

1 reference

12 December 2020

Analysis of single nucleotide polymorphisms identifies major type 1A diabetes locus telomeric of the major histocompatibility complex

1 reference

12 December 2020

Pancreas versus islet transplantation in diabetes mellitus: How to allocate deceased donor pancreata?

1 reference

12 December 2020

Initial results of screening of nondiabetic organ donors for expression of islet autoantibodies

1 reference

12 December 2020

Normal but increasing hemoglobin A1c levels predict progression from islet autoimmunity to overt type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY)

1 reference

12 December 2020

Association of the PTPN22/LYP gene with type 1 diabetes

1 reference

12 December 2020

Pancreatic autoimmunity induction with insulin B:9-23 peptide and viral mimics in the NZB mouse

1 reference

12 December 2020

TEDDY--The Environmental Determinants of Diabetes in the Young: an observational clinical trial

1 reference

12 December 2020

Dimorphic histopathology of long-standing childhood-onset diabetes

1 reference

12 December 2020

Worldwide differences in the incidence of insulin autoimmune syndrome (Hirata disease) with respect to the evolution of HLA-DR4 alleles

1 reference

12 December 2020

Peptide and major histocompatibility complex-specific breaking of humoral tolerance to native insulin with the B9-23 peptide in diabetes-prone and normal mice

1 reference

12 December 2020

Prospective study of enteroviral infections and development of beta-cell autoimmunity

1 reference

12 December 2020

Use of cod liver oil during the first year of life is associated with lower risk of childhood-onset type 1 diabetes: a large, population-based, case-control study

1 reference

12 December 2020

Recessive tolerance to preproinsulin 2 reduces but does not abolish type 1 diabetes

1 reference

12 December 2020

Expression of beta-cell autoimmunity does not differ between potential dizygotic twins and siblings of patients with type 1 diabetes

1 reference

12 December 2020

A Molecular Basis for MHC Class II—Associated Autoimmunity

1 reference

12 December 2020

Concentration of insulin autoantibodies at onset of type I diabetes. Inverse log-linear correlation with age

1 reference

12 December 2020

Combined testing of antibody titer and affinity improves insulin autoantibody measurement: Diabetes Antibody Standardization Program

1 reference

12 December 2020

Concordance for islet autoimmunity among monozygotic twins

1 reference

12 December 2020

Human regulatory CD8 T cells

1 reference

12 December 2020

SlC30A8 is a major target of humoral autoimmunity in type 1 diabetes and a predictive marker in prediabetes

1 reference

12 December 2020

Frequent induction of insulin autoantibodies by D-penicillamine in patients with rheumatoid arthritis

1 reference

12 December 2020

Recognition of human insulin in the context of HLA-DRB1*0406 products by T cells of insulin autoimmune syndrome patients and healthy donors

1 reference

12 December 2020

Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives

1 reference

12 December 2020

Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies

1 reference

12 December 2020

DRB1*04 and DQ alleles: expression of 21-hydroxylase autoantibodies and risk of progression to Addison's disease

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB09-1855

1 reference

29 July 2017

1 reference

29 July 2017

1 reference

PubMed ID

20350969