Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress. (Q34218211)

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16 February 2020

title

Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress (English)

1 reference

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16 February 2020

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GOA release 2020-03-11

author

Floris Foijer

1

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16 February 2020

Nathalie Conte

5

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16 February 2020

Stephanie Davis

6

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16 February 2020

Peter K. Sorger

10

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16 February 2020

8

Jos Jonkers

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16 February 2020

author name string

Stephanie Z Xie

2

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16 February 2020

Judith E Simon

3

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16 February 2020

Petra L Bakker

4

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16 February 2020

Eva Kregel

7

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16 February 2020

Allan Bradley

9

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16 February 2020

language of work or name

English

0 references

publication date

2 September 2014

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

16 February 2020

published in

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16 February 2020

volume

111

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16 February 2020

issue

37

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16 February 2020

page(s)

13427-13432

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25197064%20AND%20SRC:MED&resulttype=core&format=json

A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B

16 February 2020

cites work

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5 July 2018

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5 July 2018

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Cancer cells preferentially lose small chromosomes

5 July 2018

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Transcriptional consequences of aneuploidy

5 July 2018

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Mps1 at kinetochores is essential for female mouse meiosis I

5 July 2018

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Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia

5 July 2018

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ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification

5 July 2018

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Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.

5 July 2018

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Mitotic chromosomal instability and cancer: mouse modelling of the human disease.

5 July 2018

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Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity

5 July 2018

1 reference

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Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells.

5 July 2018

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Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

5 July 2018

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Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

5 July 2018

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Studying chromosome instability in the mouse

5 July 2018

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Effects of aneuploidy on cellular physiology and cell division in haploid yeast

5 July 2018

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The spindle-assembly checkpoint in space and time

5 July 2018

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Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice

5 July 2018

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Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

5 July 2018

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Generating chromosome instability through the simultaneous deletion of Mad2 and p53.

5 July 2018

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WebGestalt: an integrated system for exploring gene sets in various biological contexts

5 July 2018

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The spindle checkpoint: a quality control mechanism which ensures accurate chromosome segregation

5 July 2018

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Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.

5 July 2018

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Global up-regulation of chromosome 21 gene expression in the developing down syndrome brain

5 July 2018

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5 July 2018

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Chromosome segregation and cancer: cutting through the mystery

5 July 2018

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Cre-mediated gene deletion in the mammary gland

5 July 2018

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The spindle assembly checkpoint

5 July 2018

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T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination

5 July 2018

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5 July 2018

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The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

5 July 2018

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

5 July 2018

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BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice

5 July 2018

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Aneuploidy acts both oncogenically and as a tumor suppressor

21 January 2018

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Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

21 January 2018

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Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice.

21 January 2018

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A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

21 January 2018

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Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

21 January 2018

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Mitogen requirement for cell cycle progression in the absence of pocket protein activity

21 January 2018

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Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene

21 January 2018

1 reference

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Analysis of changes in DNA copy number in radiation-induced thymic lymphomas of susceptible C57BL/6, resistant C3H and hybrid F1 Mice

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25197064

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1400892111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25197064%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

0 references

1 reference

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16 February 2020

PubMed publication ID

25197064

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25197064%20AND%20SRC:MED&resulttype=core&format=json