Antibiotic acyldepsipeptides activate ClpP peptidase to degrade the cell division protein FtsZ (Q34221202)

31 July 2017

title

Antibiotic acyldepsipeptides activate ClpP peptidase to degrade the cell division protein FtsZ (English)

1 reference

31 July 2017

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Peter Sass

1

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author name string

Michaele Josten

2

1 reference

31 July 2017

Kirsten Famulla

3

1 reference

31 July 2017

Guido Schiffer

4

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31 July 2017

Hans-Georg Sahl

5

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31 July 2017

Leendert Hamoen

6

1 reference

31 July 2017

Heike Brötz-Oesterhelt

7

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31 July 2017

language of work or name

English

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publication date

3 October 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

published in

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31 July 2017

volume

108

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31 July 2017

issue

42

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31 July 2017

page(s)

17474-17479

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describes a project that uses

31 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3198362/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism

28 July 2018

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The antibacterial cell division inhibitor PC190723 is an FtsZ polymer-stabilizing agent that induces filament assembly and condensation.

28 July 2018

1 reference

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The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease

28 July 2018

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ClpXP protease degrades the cytoskeletal protein, FtsZ, and modulates FtsZ polymer dynamics

28 July 2018

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ClpX inhibits FtsZ assembly in a manner that does not require its ATP hydrolysis-dependent chaperone activity

28 July 2018

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Clp ATPases and ClpP proteolytic complexes regulate vital biological processes in low GC, Gram-positive bacteria

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The ClpX chaperone modulates assembly of the tubulin-like protein FtsZ.

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Crystal structure of the bacterial cell-division protein FtsZ

21 January 2018

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ClpP of Bacillus subtilis is required for competence development, motility, degradative enzyme synthesis, growth at high temperature and sporulation

21 January 2018

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The chromosome partitioning proteins Soj (ParA) and Spo0J (ParB) contribute to accurate chromosome partitioning, separation of replicated sister origins, and regulation of replication initiation in Bacillus subtilis.

21 January 2018

1 reference

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Stress induction of the Bacillus subtilis clpP gene encoding a homologue of the proteolytic component of the Clp protease and the involvement of ClpP and ClpX in stress tolerance

21 January 2018

1 reference

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Loss-of-function mutations in yjbD result in ClpX- and ClpP-independent competence development of Bacillus subtilis

21 January 2018

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The interplay of ClpXP with the cell division machinery in Escherichia coli

21 January 2018

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Multiple effects of benzamide antibiotics on FtsZ function.

21 January 2018

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Identification and characterization of the first class of potent bacterial acetyl-CoA carboxylase inhibitors with antibacterial activity

21 January 2018

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Competence in Bacillus subtilis is controlled by regulated proteolysis of a transcription factor

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.1110385108

Two-week inhalation toxicity of polymeric diphenylmethane-4, 4'-diisocyanate (PMDI) in rats: analysis of biochemical and morphological markers of early pulmonary response

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21969594

12 December 2020

inferred from PubMed ID database lookup

The FtsZ protein of Bacillus subtilis is localized at the division site and has GTPase activity that is dependent upon FtsZ concentration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21969594

12 December 2020

inferred from PubMed ID database lookup

Medicinal chemistry optimization of acyldepsipeptides of the enopeptin class antibiotics.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21969594

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1110385108

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference