Lipin-1 regulates autophagy clearance and intersects with statin drug effects in skeletal muscle (Q34221540)

31 July 2017

Lipin-1 regulates autophagy clearance and intersects with statin drug effects in skeletal muscle (English)

1 reference

31 July 2017

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3

Karen Reue

1 reference

31 July 2017

Peixiang Zhang

1

1 reference

PubMed ID

24930972

31 July 2017

M Anthony Verity

series ordinal

2

1 reference

31 July 2017

12 June 2014

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31 July 2017

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31 July 2017

20

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2

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31 July 2017

267-279

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PubMed ID

24930972

describes a project that uses

31 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4170588/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Statin myotoxicity: a review of genetic susceptibility factors

5 July 2018

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The spectrum of statin myopathy

5 July 2018

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A statin-dependent QTL for GATM expression is associated with statin-induced myopathy

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Phosphorylation of lipin 1 and charge on the phosphatidic acid head group control its phosphatidic acid phosphatase activity and membrane association

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

5 July 2018

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Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

5 July 2018

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Lipin-1 phosphatidic phosphatase activity modulates phosphatidate levels to promote peroxisome proliferator-activated receptor γ (PPARγ) gene expression during adipogenesis

5 July 2018

1 reference

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PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk

5 July 2018

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Fatty acids suppress autophagic turnover in β-cells

5 July 2018

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Protein kinase D controls voluntary-running-induced skeletal muscle remodelling

5 July 2018

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mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway

5 July 2018

1 reference

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Mice lacking microRNA 133a develop dynamin 2–dependent centronuclear myopathy

5 July 2018

1 reference

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Lipin is a central regulator of adipose tissue development and function in Drosophila melanogaster

5 July 2018

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Mitochondria removal by autophagy

5 July 2018

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Therapeutic levels of the hydroxmethylglutaryl-coenzyme A reductase inhibitor lovastatin activate ras signaling via phospholipase D2.

5 July 2018

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5 July 2018

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5 July 2018

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A diacylglycerol-dependent signaling pathway contributes to regulation of antibacterial autophagy

5 July 2018

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Termination of autophagy and reformation of lysosomes regulated by mTOR

5 July 2018

1 reference

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Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors

5 July 2018

1 reference

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5 July 2018

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5 July 2018

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5 July 2018

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Mutations in LPIN1 cause recurrent acute myoglobinuria in childhood.

5 July 2018

1 reference

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SLCO1B1 variants and statin-induced myopathy--a genomewide study

5 July 2018

1 reference

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Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.

5 July 2018

1 reference

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Autophagy in the Pathogenesis of Disease

5 July 2018

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The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity

5 July 2018

1 reference

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Diacylglycerol is required for the formation of COPI vesicles in the Golgi-to-ER transport pathway.

5 July 2018

1 reference

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Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

5 July 2018

1 reference

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LAMP proteins are required for fusion of lysosomes with phagosomes

5 July 2018

1 reference

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Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

The Saccharomyces cerevisiae Lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Lipin, a lipodystrophy and obesity gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Cellular and molecular regulation of muscle regeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Statin-associated myopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Tyrosine phosphorylation of protein kinase D in the pleckstrin homology domain leads to activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Statin-associated myopathy with normal creatine kinase levels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Alcoholic rhabdomyolysis: an experimental model in the rat.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Infantile Pompe's disease, lipid storage, and partial carnitine deficiency.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

LPIN1 gene mutations: a major cause of severe rhabdomyolysis in early childhood

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Knockout of the predominant conventional PKC isoform, PKCalpha, in mouse skeletal muscle does not affect contraction-stimulated glucose uptake.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Direct evidence for the up-regulation of Vps34 regulated by PKCgamma during short-term treatment with morphine

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Study of LPIN1, LPIN2 and LPIN3 in rhabdomyolysis and exercise-induced myalgia

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170588

Fatal rhabdomyolysis in 2 children with LPIN1 mutations

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24930972

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2014.05.003

1 reference

31 July 2017

1 reference

31 July 2017

1 reference

PubMed ID

24930972