Rho GTPase-dependent transformation by G protein-coupled receptors (Q34225958)

31 July 2017

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title

Rho GTPase-dependent transformation by G protein-coupled receptors (English)

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G protein-coupled receptor

31 July 2017

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author name string

Whitehead IP

series ordinal

1

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31 July 2017

Zohn IE

series ordinal

2

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31 July 2017

Der CJ

series ordinal

3

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31 July 2017

language of work or name

English

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publication date

1 March 2001

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31 July 2017

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31 July 2017

20

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31 July 2017

13

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31 July 2017

1547-1555

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204188

31 July 2017

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cites work

G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Chp, a homologue of the GTPase Cdc42Hs, activates the JNK pathway and is implicated in reorganizing the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Rho GTPases and their effector proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

How receptors talk to trimeric G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

The Dbl family of oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

GTPase cascades choreographing cellular behavior: movement, morphogenesis, and more

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Genomic analysis of metastasis reveals an essential role for RhoC

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Transforming G protein-coupled receptors potently activate JNK (SAPK). Evidence for a divergence from the tyrosine kinase signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Rho proteins induce metastatic properties in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

The novel Rho-family GTPase rif regulates coordinated actin-based membrane rearrangements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Thrombin receptor overexpression in malignant and physiological invasion processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Analysis of the fibroblast transformation potential of GTPase-deficient gip2 oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Identification of a novel guanine nucleotide exchange factor for the Rho GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

GTPase-deficient G alpha 16 and G alpha q induce PC12 cell differentiation and persistent activation of cJun NH2-terminal kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Role of thrombin receptor in breast cancer invasiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

G beta gamma interactions with PH domains and Ras-MAPK signaling pathways

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

The transforming activity of activated G alpha 12.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Ectopic expression of the serotonin 1c receptor and the triggering of malignant transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Two G protein oncogenes in human endocrine tumors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Guanine nucleotide exchange factor GEF115 specifically mediates activation of Rho and serum response factor by the G protein alpha subunit Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

A role for Rac in Tiam1-induced membrane ruffling and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Cloning and Functional Characterization of a Novelmas-Related Gene, Modulating Intracellular Angiotensin II Actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Gq and G11 are concurrently activated by bombesin and vasopressin in Swiss 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

A mutant alpha subunit of Gi2 induces neoplastic transformation of Rat-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Changes in inositol lipids and phosphates after stimulation of the MAS-transfected NG115-401L-C3 cell line by mitogenic and non-mitogenic stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

An essential role for Rac in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

A role for Rho in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Rho: theme and variations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

RTA, a candidate G protein-coupled receptor: cloning, sequencing, and tissue distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Structure and function of G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

The Rac and Rho pathways as a source of drug targets for Ras-mediated malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Rho GTPases and signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Characterization of TCL, a new GTPase of the rho family related to TC10 andCcdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Expression cloning of lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Expression cloning of oncogenes by retroviral transfer of cDNA libraries

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Lysophospholipids activate ovarian and breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

G2A is an oncogenic G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Mas oncogene signaling and transformation require the small GTP-binding protein Rac

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Angiotensin II stimulates calcium-dependent activation of c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

Regulation of cell proliferation by G proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

7 January 2021

A family of receptors coupled to guanine nucleotide regulatory proteins

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

7 January 2021

Rho as a mediator of G protein-coupled receptor signaling.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

7 January 2021

The family of G-protein-coupled receptors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

1 reference

7 January 2021

Characterization of the rat mas oncogene and its high-level expression in the hippocampus and cerebral cortex of rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204188

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204188

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Dimensions Publication ID

31 July 2017

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