Dysfunctional CD8+ T cells in hepatitis B and C are characterized by a lack of antigen-specific T-bet induction (Q34230513)

31 July 2017

title

Dysfunctional CD8+ T cells in hepatitis B and C are characterized by a lack of antigen-specific T-bet induction (English)

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31 July 2017

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Clemens-Martin Wendtner

6

object named as

Clemens-Martin Wendtner

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31 July 2017

Peter D Kurktschiev

1

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31 July 2017

Bijan Raziorrouh

2

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31 July 2017

Winfried Schraut

3

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31 July 2017

Markus Backmund

4

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31 July 2017

Martin Wächtler

5

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31 July 2017

Bertram Bengsch

7

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31 July 2017

Robert Thimme

8

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31 July 2017

Gerald Denk

9

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31 July 2017

Reinhart Zachoval

10

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31 July 2017

Andrea Dick

11

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31 July 2017

Michael Spannagl

12

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31 July 2017

Jürgen Haas

13

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31 July 2017

Helmut M Diepolder

14

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31 July 2017

Maria-Christina Jung

15

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31 July 2017

Norbert H Gruener

16

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31 July 2017

language of work or name

English

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publication date

15 September 2014

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Journal of Experimental Medicine

31 July 2017

published in

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31 July 2017

volume

211

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31 July 2017

issue

10

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31 July 2017

page(s)

2047-2059

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The third signal cytokine IL-12 rescues the anti-viral function of exhausted HBV-specific CD8 T cells

31 July 2017

cites work

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6 July 2018

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Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.

6 July 2018

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6 July 2018

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Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection.

6 July 2018

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Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages

6 July 2018

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Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression

6 July 2018

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Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

6 July 2018

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Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination

6 July 2018

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Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

6 July 2018

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Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.

6 July 2018

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Tracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection

6 July 2018

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Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection

6 July 2018

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Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection

6 July 2018

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Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo

6 July 2018

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Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin

6 July 2018

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The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity

6 July 2018

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Hepatitis C virus core selectively suppresses interleukin-12 synthesis in human macrophages by interfering with AP-1 activation

6 July 2018

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Antigen-driven effector CD8 T cell function regulated by T-bet

6 July 2018

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Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin

6 July 2018

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Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection

6 July 2018

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CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection

6 July 2018

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T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

6 July 2018

1 reference

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Hepatitis C virus infection

6 July 2018

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Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

6 July 2018

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Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation

6 July 2018

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Analysis of successful immune responses in persons infected with hepatitis C virus

6 July 2018

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A novel transcription factor, T-bet, directs Th1 lineage commitment

6 July 2018

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Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C

6 July 2018

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A phase I/II study of recombinant human interleukin-12 in patients with chronic hepatitis C.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection

6 July 2018

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https://api.crossref.org/works/10.1084%2FJEM.20131333

CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained

21 January 2018

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https://api.crossref.org/works/10.1084%2FJEM.20131333

Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20131333

Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20131333

Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses.

21 January 2018

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https://api.crossref.org/works/10.1084%2FJEM.20131333

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21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

A phase I/II study of recombinant human interleukin-12 in patients with chronic hepatitis B

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25225458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Common HLA-B8-DR3 haplotype in Northern India is different from that found in Europe

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25225458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IL-12 up-regulates T-bet independently of IFN-gamma in human CD4+ T cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25225458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20131333

1 reference

31 July 2017

1 reference

31 July 2017

1 reference