αA-Crystallin associates with α6 integrin receptor complexes and regulates cellular signaling. (Q34233267)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20709056%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

αA-Crystallin associates with α6 integrin receptor complexes and regulates cellular signaling (English)

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10 February 2020

2

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10 February 2020

author name string

A Sue Menko

series ordinal

1

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10 February 2020

publication date

13 August 2010

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Experimental Eye Research

10 February 2020

published in

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10 February 2020

volume

91

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10 February 2020

issue

5

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10 February 2020

page(s)

640-651

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Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival

10 February 2020

cites work

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Identification of a novel intermediate filament-linked N-cadherin/gamma-catenin complex involved in the establishment of the cytoarchitecture of differentiated lens fiber cells

6 July 2018

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Mechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death

6 July 2018

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Heat shock genes - integrating cell survival and death

6 July 2018

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6 July 2018

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6 July 2018

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Crystallins in the eye: Function and pathology

6 July 2018

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Cell signaling pathways to alphaB-crystallin following stresses of the cytoskeleton

6 July 2018

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Alpha-crystallin expression affects microtubule assembly and prevents their aggregation

6 July 2018

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Caspase-dependent secondary lens fiber cell disintegration in alphaA-/alphaB-crystallin double-knockout mice

6 July 2018

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Regulation of cadherin-mediated adhesion in morphogenesis

6 July 2018

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Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by alpha B-crystallin through inhibition of RAS activation

6 July 2018

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Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry

6 July 2018

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Expression and regulation of alpha-, beta-, and gamma-crystallins in mammalian lens epithelial cells

6 July 2018

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Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

6 July 2018

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A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells

6 July 2018

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Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q

6 July 2018

1 reference

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Reduced survival of lens epithelial cells in the alphaA-crystallin-knockout mouse

6 July 2018

1 reference

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Chaperoning signaling pathways: molecular chaperones as stress-sensing 'heat shock' proteins.

6 July 2018

1 reference

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Small stress proteins: novel negative modulators of apoptosis induced independently of reactive oxygen species.

6 July 2018

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sHsp-phosphorylation: enzymes, signaling pathways and functional implications

6 July 2018

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Role for alpha 6 integrin during lens development: Evidence for signaling through IGF-1R and ERK.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

alpha-Crystallin chaperone-like activity and membrane binding in age-related cataracts

6 July 2018

1 reference

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The R116C mutation in alpha A-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Human bcl-2 gene attenuates the ability of rabbit lens epithelial cells against H2O2-induced apoptosis through down-regulation of the alpha B-crystallin gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Interaction between alphaB-crystallin and the human 20S proteasomal subunit C8/alpha7.

6 July 2018

1 reference

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Changes in adhesion complexes define stages in the differentiation of lens fiber cells.

6 July 2018

1 reference

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Differential protective activity of alpha A- and alphaB-crystallin in lens epithelial cells.

6 July 2018

1 reference

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The function of alpha-crystallin in vision

6 July 2018

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Characterization of alpha-crystallin-plasma membrane binding

6 July 2018

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AlphaB-crystallin selectively targets intermediate filament proteins during thermal stress

6 July 2018

1 reference

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The molecular chaperone alphaA-crystallin enhances lens epithelial cell growth and resistance to UVA stress

6 July 2018

1 reference

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Expression of growth control and differentiation genes in human lens epithelial cells with extended life span

6 July 2018

1 reference

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Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Cloning, expression, and chaperone-like activity of human alphaA-crystallin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Cell adhesion: the molecular basis of tissue architecture and morphogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Regulation of alpha 6 beta 1 integrin laminin receptor function by the cytoplasmic domain of the alpha 6 subunit

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Propagation and immortalization of human lens epithelial cells in culture.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Chaperone activity of alpha-crystallins modulates intermediate filament assembly.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Expression of the alpha-crystallin/small heat-shock protein/molecular chaperone genes in the lens and other tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Lens epithelial cell apoptosis appears to be a common cellular basis for non-congenital cataract development in humans and animals

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Beta 1 integrins in epithelial tissues: a unique distribution in the lens

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Lens differentiation in vertebrates. A review of cellular and molecular features

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

alpha B subunit of lens-specific protein alpha-crystallin is present in other ocular and non-ocular tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Expression of the murine alpha B-crystallin gene is not restricted to the lens

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

The major laminin receptor of mouse embryonic stem cells is a novel isoform of the alpha 6 beta 1 integrin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Alpha-crystallin can function as a molecular chaperone

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

alphaB-crystallin suppresses oxidative stress-induced astrocyte apoptosis by inhibiting caspase-3 activation

6 July 2018

1 reference

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Mechanism of Src kinase induction of cortical cataract following exposure to stress: destabilization of cell-cell junctions.

28 October 2018

1 reference

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Phosphoinositide 3-kinase signaling to Akt promotes keratinocyte differentiation versus death.

28 October 2018

1 reference

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Stabilization of integrin-linked kinase by binding to Hsp90.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

alpha-Crystallin localizes to the leading edges of migrating lens epithelial cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

The canonical intrinsic mitochondrial death pathway has a non-apoptotic role in signaling lens cell differentiation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Molecular chaperones and the stress of oncogenesis

28 October 2018

1 reference

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A signaling role for the uncleaved form of alpha 6 integrin in differentiating lens fiber cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

CNS integrins switch growth factor signalling to promote target-dependent survival

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Transition between proliferation and differentiation for lens epithelial cells is regulated by Src family kinases

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

Systematic analysis of E-, N- and P-cadherin expression in mouse eye development.

28 October 2018

1 reference

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The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

N-cadherin function is required for differentiation-dependent cytoskeletal reorganization in lens cells in vitro.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

AlphaB-crystallin regulates intermediate filament organization in situ

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

HSP27 inhibits cytochrome c-dependent activation of procaspase-9.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

alpha6 Integrin is regulated with lens cell differentiation by linkage to the cytoskeleton and isoform switching.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962712

6beta4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF- B-dependent resistance to apoptosis in 3D mammary acini

28 October 2018

1 reference

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Interactions between important regulatory proteins and human alphaB crystallin

9 December 2018

1 reference

12 December 2020

Differential expression of N- and B-cadherin during lens development

1 reference

12 December 2020

Lens epithelial cells derived from alphaB-crystallin knockout mice demonstrate hyperproliferation and genomic instability

1 reference

12 December 2020

The small heat-shock protein alpha B-crystallin promotes FBX4-dependent ubiquitination

1 reference

12 December 2020

Alpha crystallin from human cataractous vs. normal lenses: change in binding to lens membrane

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12 December 2020

Specificity of alpha crystallin binding to the lens membrane

1 reference

12 December 2020

Involvement of the N-terminal region in alpha-crystallin-lens membrane recognition

1 reference

12 December 2020

10.1016/J.EXER.2010.08.006

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20709056%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20709056%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference