The neuroimmunology of multiple sclerosis: possible roles of T and B lymphocytes in immunopathogenesis (Q34238431)

31 July 2017

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title

The neuroimmunology of multiple sclerosis: possible roles of T and B lymphocytes in immunopathogenesis (English)

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31 July 2017

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3

Hafler DA

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31 July 2017

O'Connor KC

1

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31 July 2017

Bar-Or A

series ordinal

2

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31 July 2017

language of work or name

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1 March 2001

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Journal of Clinical Immunology

31 July 2017

published in

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31 July 2017

volume

21

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31 July 2017

issue

2

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31 July 2017

page(s)

81-92

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Immunoglobulin-deficient rats fail to develop experimental allergic encephalomyelitis

31 July 2017

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12 December 2020

B-cell-deficient mice develop experimental allergic encephalomyelitis with demyelination after myelin oligodendrocyte glycoprotein sensitization

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12 December 2020

Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients. A marker of activated/memory T cells

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Anti-cardiolipin antibodies in neurological disorders: cross-reaction with anti-single stranded DNA activity

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Cerebrospinal fluid in the diagnosis of multiple sclerosis: a consensus report

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Oligodendrocyte-specific expression and autoantigenicity of transaldolase in multiple sclerosis

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12 December 2020

An extensive search for autoantibodies to myelin basic protein in cerebrospinal fluid of non-multiple-sclerosis patients: implications for the pathogenesis of multiple sclerosis

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12 December 2020

Oligoclonal immunoglobulins and plasma cells in spinal fluid of patients with multiple sclerosis

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Matrix metalloproteinases in the normal human central nervous system, microglial nodules, and multiple sclerosis lesions

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12 December 2020

Clonal expansion and somatic hypermutation of V(H) genes of B cells from cerebrospinal fluid in multiple sclerosis.

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12 December 2020

Multiple sclerosis: cells secreting antibodies against myelin-associated glycoprotein are present in cerebrospinal fluid

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12 December 2020

T and B cell responses to myelin-oligodendrocyte glycoprotein in multiple sclerosis

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12 December 2020

Patterns of cytokine secretion by autoreactive proteolipid protein-specific T cell clones during the course of multiple sclerosis

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12 December 2020

B cell repertoire diversity and clonal expansion in multiple sclerosis brain lesions

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12 December 2020

TIMP-2 reduces proteolytic opening of blood-brain barrier by type IV collagenase

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12 December 2020

Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system

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12 December 2020

Cytokine phenotype of human autoreactive T cell clones specific for the immunodominant myelin basic protein peptide (83-99).

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12 December 2020

The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement.

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12 December 2020

A correlation between cerebrospinal fluid myelin basic protein and anti-myelin basic protein in multiple sclerosis patients

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12 December 2020

Genetics of multiple sclerosis

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12 December 2020

Cytokines induce the development of functionally heterogeneous T helper cell subsets

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12 December 2020

Antibodies to myelin-oligodendrocyte glycoprotein in cerebrospinal fluid from patients with multiple sclerosis and controls

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12 December 2020

Antimyelin basic protein and antimyelin antibody-producing cells in multiple sclerosis

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12 December 2020

Anti-myelin basic protein and anti-proteolipid protein specific forms of multiple sclerosis

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12 December 2020

Total, anti-viral, and anti-myelin IgG subclass reactivity in inflammatory diseases of the central nervous system

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12 December 2020

Autoreactive T and B cells responding to myelin proteolipid protein in multiple sclerosis and controls

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12 December 2020

Autoantibodies to myelin basic protein are not present in the serum and CSF of MS patients

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12 December 2020

Immune regulation and CNS autoimmune disease.

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12 December 2020

Immunoglobulin G, A, and M--clonal restriction in multiple sclerosis cerebrospinal fluid and serum--analysis by two-dimensional electrophoresis

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12 December 2020

Distinct roles for B7-1 (CD-80) and B7-2 (CD-86) in the initiation of experimental allergic encephalomyelitis

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12 December 2020

A study of the crystalline albumin, gamma globulin and total protein in the cerebrospinal fluid of 100 cases of multiple sclerosis and in other diseases

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12 December 2020

Herpes simplex virus encephalitis: Intrathecal synthesis of oligoclonal virus-specific IgG, IgA and IgM antibodies

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12 December 2020

A population-based study of multiple sclerosis in twins: update.

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12 December 2020

Response of human T lymphocyte lines to myelin basic protein: association of dominant epitopes with HLA class II restriction molecules

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12 December 2020

Histocompatibility determinants in multiple sclerosis, with special reference to clinical course

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12 December 2020

Local gene therapy with CTLA4-immunoglobulin fusion protein in experimental allergic encephalomyelitis.

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12 December 2020

Distribution of immunoglobulin superfamily members ICAM-1, -2, -3, and the beta 2 integrin LFA-1 in multiple sclerosis lesions.

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12 December 2020

Reactivity to myelin antigens in multiple sclerosis. Peripheral blood lymphocytes respond predominantly to myelin oligodendrocyte glycoprotein

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12 December 2020

The Dale E. McFarlin Memorial Lecture: the immunology of the multiple sclerosis lesion

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12 December 2020

Molecular mimicry and multiple sclerosis: degenerate T-cell recognition and the induction of autoimmunity

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12 December 2020

T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

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12 December 2020

Comparison of immunoglobulin G heavy-chain sequences in MS and SSPE brains reveals an antigen-driven response

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12 December 2020

Differential expression of inflammatory cytokines parallels progression of central nervous system pathology in two clinically distinct models of multiple sclerosis

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12 December 2020

Oligoclonal IgG bands in plaques from multiple sclerosis brains

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12 December 2020

Expression of immunologically relevant endothelial cell activation antigens on isolated central nervous system microvessels from patients with multiple sclerosis

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12 December 2020

The British Isles survey of multiple sclerosis in twins

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12 December 2020

T cells responsive to myelin basic protein in patients with multiple sclerosis

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12 December 2020

Intrathecal immunoglobulin M synthesis in multiple sclerosis. Relationship with clinical and cerebrospinal fluid parameters

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12 December 2020

Prevalence and Clinical Significance of Anti-phospholipid Antibodies in Multiple Sclerosis: a Study of 89 Patients

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12 December 2020

Oligoclonal IgG bands in cerebrospinal fluid. Methodological and clinical aspects

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12 December 2020

Cytokine secretion of myelin basic protein reactive T cells in patients with multiple sclerosis

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12 December 2020

T cell gelatinases mediate basement membrane transmigration in vitro.

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12 December 2020

Autoantibodies to myelin basic protein within multiple sclerosis central nervous system tissue

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12 December 2020

Multiple sclerosis: a quantitative and qualitative study of immunoglobulin-containing cells in the central nervous system

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12 December 2020

Viral and bacterial antibody responses in multiple sclerosis

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12 December 2020

Frequency of anti-nuclear antibodies in multiple sclerosis

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12 December 2020

Twin study of multiple sclerosis: An epidemiologic inquiry

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12 December 2020

Identification of autoantibodies associated with myelin damage in multiple sclerosis

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12 December 2020

B7/BB-1 antigen expression on adult human microglia studied in vitro and in situ

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12 December 2020

Increased CD80(+) B cells in active multiple sclerosis and reversal by interferon beta-1b therapy

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12 December 2020

T cell recognition of immunodominant and cryptic proteolipid protein epitopes in humans.

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12 December 2020

Macrophages, lymphocytes, and plasma cells in the perivascular compartment in chronic multiple sclerosis

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12 December 2020

Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis

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12 December 2020

The differential diagnosis of neurological diseases by fractionating electrophoretically the CSF gamma-globulins

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12 December 2020

An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease.

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12 December 2020

T helper 1 and T helper 2 cells respond differentially to chemokines

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12 December 2020

Antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: a comparative study

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12 December 2020

Autoantibodies in neurodegenerative diseases: antigen-specific frequencies and intrathecal analysis

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12 December 2020

Comparative analysis of antibody and cell-mediated autoimmunity to transaldolase and myelin basic protein in patients with multiple sclerosis

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12 December 2020

Matrix metalloproteinases in inflammatory demyelination: targets for treatment

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12 December 2020

Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals

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12 December 2020

CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions

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12 December 2020

Tumor necrosis factor identified in multiple sclerosis brain

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12 December 2020

Affinity of antigen-specific IgG distinguishes multiple sclerosis from encephalitis

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12 December 2020

Chemokines and chemokine receptors in the pathogenesis of multiple sclerosis

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12 December 2020

Multiple sclerosis. Electrofocused "bands" of oligoclonal CSF IgG do not carry antibody activity against measles, varicella-zoster or rotaviruses

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12 December 2020

Alterations in levels of CD28-/CD8+ suppressor cell precursor and CD45RO+/CD4+ memory T lymphocytes in the peripheral blood of multiple sclerosis patients

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12 December 2020

Targeting the B7/CD28:CTLA-4 costimulatory system in CNS autoimmune disease

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12 December 2020

Measles antibodies in multiple sclerosis.

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12 December 2020

92 kDa type IV collagenase (MMP-9) is expressed in neutrophils and macrophages but not in malignant epithelial cells in human colon cancer

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12 December 2020

Blockade of CD28/B7-1 interaction prevents epitope spreading and clinical relapses of murine EAE

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12 December 2020

Relative frequency of autoantibodies to myelin basic protein and proteolipid protein in optic neuritis and multiple sclerosis cerebrospinal fluid

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12 December 2020

Multiple sclerosis: B- and T-cell responses to the extracellular domain of the myelin oligodendrocyte glycoprotein.

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12 December 2020

Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

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12 December 2020

Matrix metalloproteinase expression in an experimentally-induced DTH model of multiple sclerosis in the rat CNS.

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12 December 2020

Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions

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12 December 2020

Kinetics of expression of costimulatory molecules and their ligands in murine relapsing experimental autoimmune encephalomyelitis in vivo.

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12 December 2020

B cells expressing CD5 are increased in cerebrospinal fluid of patients with multiple sclerosis

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12 December 2020

Bound antibody in multiple sclerosis brains

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12 December 2020

Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice

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12 December 2020

Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSF, and two pentapeptide sequence identities between EBNA and myelin basic protein

1 reference

12 December 2020

Importance of intrathecal synthesis of IgD in multiple sclerosis. A combined clinical, immunologic, and magnetic resonance imaging study

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12 December 2020

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

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12 December 2020

Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients

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12 December 2020

Extended major histocompatibility complex haplotypes in patients with multiple sclerosis

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12 December 2020

Isoelectric focusing of IgG eluted from multiple sclerosis and subacute sclerosing panencephalitis brains

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12 December 2020

Inflammatory cytokines in the brain: does the CNS shape immune responses?

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12 December 2020

Isolation of myelin basic protein-reactive T-cell lines from normal human blood

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12 December 2020

The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis

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12 December 2020

Myelin basic protein‐specific T lymphocyte lines from MS patients and healthy individuals

1 reference

12 December 2020

Epitope spreading: the role of self peptides and autoantigen processing by B lymphocytes

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12 December 2020

The adhesion molecule and cytokine profile of multiple sclerosis lesions

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12 December 2020

Candidate autoantigens in multiple sclerosis

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12 December 2020

Myelin basic protein: a component of circulating immune complexes in multiple sclerosis

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12 December 2020

Genetic susceptibility to multiple sclerosis. A co-twin study of a nationwide series

1 reference

12 December 2020

Evidence for multiple human T cell recognition sites on myelin basic protein

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12 December 2020

Preferential synthesis of the G1m(1) allotype of IgG1 in the central nervous system of multiple sclerosis patients

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12 December 2020

Antibodies to myelin-associated glycoprotein (MAG) in the cerebrospinal fluid of multiple sclerosis patients.

1 reference

12 December 2020

Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy

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12 December 2020

Quantitative estimation of the albumin and gamma globulin in normal and pathologic cerebrospinal fluid by immunochemical methods

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12 December 2020

Expression of IL-12 in CNS and lymphoid organs of mice with experimental allergic encephalitis

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12 December 2020

Antibody facilitation of multiple sclerosis-like lesions in a nonhuman primate.

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12 December 2020

Isolation of myelin basic protein-specific T cells predominantly from the memory T-cell compartment in multiple sclerosis

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12 December 2020

Accumulation of clonally related B lymphocytes in the cerebrospinal fluid of multiple sclerosis patients

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12 December 2020

Functional diversity of helper T lymphocytes

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12 December 2020

CD5+ B cells and CD4-8-T cells in neuroimmunological diseases

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12 December 2020

Oligoclonal IgG and Free Light Chains in the Cerebrospinal Fluid of Patients with Multiple Sclerosis and Infectious Diseases of the Central Nervous System

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12 December 2020

Interferon-beta interferes with the proliferation but not with the cytokine secretion of myelin basic protein-specific, T-helper type 1 lymphocytes

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12 December 2020

Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone

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12 December 2020

Cytokine profile of myelin basic protein-reactive T cells in multiple sclerosis and healthy individuals.

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12 December 2020

Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4,

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12 December 2020

Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation

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12 December 2020

Degeneracy in T-cell antigen recognition - implications for the pathogenesis of autoimmune diseases.

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12 December 2020

Synergy between encephalitogenic T cells and myelin basic protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis

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12 December 2020

A humoral response to oligodendrocyte-specific protein in MS: a potential molecular mimic

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12 December 2020

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

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12 December 2020

The intrathecal immune response in the early stage of multiple sclerosis

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12 December 2020

The Expression of Tissue-type Plasminogen Activator, Matrix Metalloproteases and Endogenous Inhibitors in the Central Nervous System in Multiple Sclerosis

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12 December 2020

Mechanisms of inflammation in MS tissue: adhesion molecules and chemokines

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12 December 2020

Matrix metalloproteinases and diseases of the CNS.

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12 December 2020

CSF antibody to myelin basic protein. Measurement in patients with multiple sclerosis and subacute sclerosing panencephalitis

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12 December 2020

Regulation of the inflammatory response in animal models of multiple sclerosis by interleukin-12.

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12 December 2020

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

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12 December 2020

The effects of interferon-gamma on the central nervous system.

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12 December 2020

Autoimmunity in multiple sclerosis: study of a wide spectrum of autoantibodies.

1 reference

12 December 2020

Oligoclonal measles virus-specific IgG antibodies isolated from cerebrospinal fluids, brain extracts, and sera from patients with subacute sclerosing panencephalitis and multiple sclerosis

1 reference

12 December 2020

Cytokine localization in multiple sclerosis lesions: correlation with adhesion molecule expression and reactive nitrogen species

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12 December 2020

The ups and downs of T cell costimulation

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12 December 2020

Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions

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12 December 2020

Analysis of cerebrospinal fluid and serum of patients with multiple sclerosis by means of anti-idiotypic antisera

1 reference

12 December 2020

Injury-induced 92-kilodalton gelatinase and urokinase expression in rat brain.

1 reference

12 December 2020

Clonal expansion and persistence of human T cells specific for an immunodominant myelin basic protein peptide

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1011064007686

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Dimensions Publication ID

31 July 2017

1030020027

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