A novel activity of microsomal epoxide hydrolase: metabolism of the endocannabinoid 2-arachidonoylglycerol. (Q34238687)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24958911%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

A novel activity of microsomal epoxide hydrolase: metabolism of the endocannabinoid 2-arachidonoylglycerol (English)

1 reference

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21 March 2020

main subject

endocannabinoids

0 references

glyceryl 2-arachidonate

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Epoxide hydrolase 1

1 reference

cis-stilbene-oxide hydrolase activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Michael P Endsley

2

1 reference

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21 March 2020

author name string

Kasem Nithipatikom

1

1 reference

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21 March 2020

Adam W Pfeiffer

3

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21 March 2020

John R Falck

4

1 reference

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21 March 2020

William B Campbell

5

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21 March 2020

publication date

23 June 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24958911%20AND%20SRC:MED&resulttype=core&format=json

Journal of Lipid Research

21 March 2020

published in

1 reference

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21 March 2020

volume

55

1 reference

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21 March 2020

issue

10

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21 March 2020

page(s)

2093-2102

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Dynamic changes to the endocannabinoid system in models of chronic pain

21 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Monoclonal antibodies reveal multiple forms of expression of human microsomal epoxide hydrolase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

The role of endocannabinoids in pain modulation and the therapeutic potential of inhibiting their enzymatic degradation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Anti-proliferative effect of a putative endocannabinoid, 2-arachidonylglyceryl ether in prostate carcinoma cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Inhibition of monoacylglycerol lipase by troglitazone, N‐arachidonoyl dopamine and the irreversible inhibitor JZL184: comparison of two different assays

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Mammalian epoxide hydrolases in xenobiotic metabolism and signalling.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Expression and function of fatty acid amide hydrolase in prostate cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: Location, hydrolysis and 12-lipoxygenase metabolism.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Identification of a novel endocannabinoid-hydrolyzing enzyme expressed by microglial cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Mechanism of carbamate inactivation of FAAH: implications for the design of covalent inhibitors and in vivo functional probes for enzymes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

An endocannabinoid mechanism for stress-induced analgesia.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Epoxide hydrolases: their roles and interactions with lipid metabolism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

2-arachidonoylglycerol: a novel inhibitor of androgen-independent prostate cancer cell invasion.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Brain monoglyceride lipase participating in endocannabinoid inactivation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Epoxide hydrolases: biochemistry and molecular biology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

The x-ray structure of epoxide hydrolase from Agrobacterium radiobacter AD1. An enzyme to detoxify harmful epoxides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Bile acid transport into hepatocyte smooth endoplasmic reticulum vesicles is mediated by microsomal epoxide hydrolase, a membrane protein exhibiting two distinct topological orientations.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Endogenous role of microsomal epoxide hydrolase. Ontogenesis, induction inhibition, tissue distribution, immunological behaviour and purification of microsomal epoxide hydrolase with 16 alpha, 17 alpha-epoxyandrostene-3-one as substrate.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Differential regulation of two microsomal epoxide hydrolases in hyperplastic nodules from rat liver

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Drug metabolism in carcinogenesis and cancer chemotherapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

The alpha/beta hydrolase fold

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174002

Endogenous Role of Microsomal Epoxide Hydrolase

6 July 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M051284

Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M051284

Inhibition of microsomal epoxide hydrolases by ureas, amides, and amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M051284

Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M051284

Liquid chromatographic-electrospray ionization-mass spectrometric analysis of cytochrome P450 metabolites of arachidonic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M051284

The effects of peptide and lipid endocannabinoids on arthritic pain at the spinal level

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M051284

Co-purification of microsomal epoxide hydrolase with the warfarin-sensitive vitamin K1 oxide reductase of the vitamin K cycle

21 January 2018

1 reference

12 December 2020

Structure activity relationship of human microsomal epoxide hydrolase inhibition by amide and acid analogues of valproic acid

1 reference

12 December 2020

Induction of rat liver microsomal epoxide hydrolase by its endogenous substrate 16 alpha, 17 alpha-epoxyestra-1,3,5-trien-3-ol

1 reference

12 December 2020

Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.M051284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24958911%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24958911%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

24958911

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24958911%20AND%20SRC:MED&resulttype=core&format=json