Identification of novel γ-secretase-associated proteins in detergent-resistant membranes from brain (Q34252876)

31 July 2017

Identification of novel γ-secretase-associated proteins in detergent-resistant membranes from brain (English)

1 reference

31 July 2017

8

Bengt Winblad

1 reference

31 July 2017

Ji-Yeun Hur

1

1 reference

31 July 2017

Yasuhiro Teranishi

2

1 reference

31 July 2017

Takahiro Kihara

3

1 reference

31 July 2017

Natsuko Goto Yamamoto

4

1 reference

31 July 2017

Mitsuhiro Inoue

5

1 reference

31 July 2017

Waltteri Hosia

6

1 reference

31 July 2017

Masakazu Hashimoto

7

1 reference

31 July 2017

Susanne Frykman

9

1 reference

31 July 2017

Lars O Tjernberg

10

1 reference

31 July 2017

language of work or name

English

0 references

publication date

7 February 2012

1 reference

Journal of Biological Chemistry

31 July 2017

1 reference

31 July 2017

287

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31 July 2017

15

1 reference

31 July 2017

11991-12005

1 reference

Perspective: in search of biomarkers.

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Therapeutic intervention for Alzheimer's disease with γ-secretase inhibitors: still a viable option?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Isolation of detergent resistant microdomains from cultured neurons: detergent dependent alterations in protein composition

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

A domain level interaction network of amyloid precursor protein and Abeta of Alzheimer's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Affinity pulldown of γ-secretase and associated proteins from human and rat brain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Mitochondrial accumulation of APP and Abeta: significance for Alzheimer disease pathogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

TMP21 transmembrane domain regulates gamma-secretase cleavage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Purification, pharmacological modulation, and biochemical characterization of interactors of endogenous human gamma-secretase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Mutations in contactin-1, a neural adhesion and neuromuscular junction protein, cause a familial form of lethal congenital myopathy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

BRI2 inhibits amyloid beta-peptide precursor protein processing by interfering with the docking of secretases to the substrate.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

The ratio of monomeric to aggregated forms of Abeta40 and Abeta42 is an important determinant of amyloid-beta aggregation, fibrillogenesis, and toxicity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Amyloid beta-peptide levels in laser capture microdissected cornu ammonis 1 pyramidal neurons of Alzheimer's brain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Rapid preparation of nuclei-depleted detergent-resistant membrane fractions suitable for proteomics analysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Active gamma-secretase is localized to detergent-resistant membranes in human brain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

The in vivo brain interactome of the amyloid precursor protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

When loss is gain: reduced presenilin proteolytic function leads to increased Abeta42/Abeta40. Talking Point on the role of presenilin mutations in Alzheimer disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Notch signalling: a simple pathway becomes complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

BACE1 interacts with lipid raft proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Oxidation-reduction respiratory chains and ATP synthase complex are localized in detergent-resistant lipid rafts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Proteomics of plasma membrane microdomains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Spatial segregation of gamma-secretase and substrates in distinct membrane domains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Mass spectrometric analysis of the glycosphingolipid-enriched microdomains of rat natural killer cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Neuronal membrane cholesterol loss enhances amyloid peptide generation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Caspr regulates the processing of contactin and inhibits its binding to neurofascin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Identity and function of γ‐secretase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Resistance of cell membranes to different detergents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Monocyte lipid rafts contain proteins implicated in vesicular trafficking and phagosome formation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Oligomeric state and stoichiometry of p24 proteins in the early secretory pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Axon-glia interactions and the domain organization of myelinated axons requires neurexin IV/Caspr/Paranodin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Alzheimer's disease: genes, proteins, and therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

Presenilin, Notch, and the genesis and treatment of Alzheimer's disease

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Abeta43 is more frequent than Abeta40 in amyloid plaque cores from Alzheimer disease brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Reconstitution of gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Functional rafts in cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Partial Purification and Characterization of γ-Secretase from Post-mortem Human Brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

A detergent-insoluble membrane compartment contains A beta in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Association of active gamma-secretase complex with lipid rafts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

High recovery HPLC separation of lipid rafts for membrane proteome analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Lipid raft proteome reveals ATP synthase complex in the cell surface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Quantitative profiling of the detergent-resistant membrane proteome of iota-b toxin induced vero cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Lipid raft proteomics: analysis of in-solution digest of sodium dodecyl sulfate-solubilized lipid raft proteins by liquid chromatography-matrix-assisted laser desorption/ionization tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Identification of syntaxin 1A as a novel binding protein for presenilin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

VDAC and ERalpha interaction in caveolae from human cortex is altered in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Cellular form of prion protein inhibits Reelin-mediated shedding of Caspr from the neuronal cell surface to potentiate Caspr-mediated inhibition of neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.246074

Contactin-associated protein (Caspr) and contactin form a complex that is targeted to the paranodal junctions during myelination.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320946

28 October 2018

Identifiers

DOI

10.1074/JBC.M111.246074

1 reference

31 July 2017

1 reference

31 July 2017

1 reference